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SLC25A2 Gene

protein-coding   GIFtS: 53
GCID: GC05M140662

Solute Carrier Family 25 (Mitochondrial Carrier; Ornithine...

  See SLC25A2-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 25 (Mitochondrial Carrier; Ornithine Transporter)
Member 21 2
ORNT22 3 5
Solute Carrier Family 25 Member 22 3
ORC22
Mitochondrial Ornithine Transporter 22
Ornithine Transporter 22

External Ids:    HGNC: 229211   Entrez Gene: 838842   Ensembl: ENSG000001203297   OMIM: 6081575   UniProtKB: Q9BXI23   

Export aliases for SLC25A2 gene to outside databases

Previous GC identifers: GC05M140665 GC05M140710 GC05M135827


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC25A2 Gene:
Located between the protocadherin beta and gamma gene clusters on chromosome 5, this intronless gene encodes a
protein that is highly similar to an ornithine transporter localized in the mitochondrial inner membrane. The
encoded protein most likely plays a role in metabolism as a mitochondrial transport protein. (provided by RefSeq,
Jul 2008)

GeneCards Summary for SLC25A2 Gene:
SLC25A2 (solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2) is a protein-coding gene. Diseases associated with SLC25A2 include urea cycle disorder, and ornithine translocase deficiency. GO annotations related to this gene include L-ornithine transmembrane transporter activity. An important paralog of this gene is SLC25A15.

UniProtKB/Swiss-Prot: ORNT2_HUMAN, Q9BXI2
Function: Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000005.9  NC_018916.2  NT_029289.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC25A2 gene promoter:
         AP-1   Sp1   NCX/Ncx   Gfi-1   Evi-1   GATA-1   AREB6   POU2F1a   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC25A2 promoter sequence
   Search Chromatin IP Primers for SLC25A2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC25A2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31   Ensembl cytogenetic band:  5q31.3   HGNC cytogenetic band: 5q31.3

SLC25A2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC25A2 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M140662:  view genomic region     (about GC identifiers)

Start:
140,682,196 bp from pter      End:
140,683,612 bp from pter
Size:
1,417 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ORNT2_HUMAN, Q9BXI2 (See protein sequence)
Recommended Name: Mitochondrial ornithine transporter 2  
Size: 301 amino acids; 32580 Da
Secondary accessions: Q496C1 Q6XUI0 Q8NFZ2

Explore the universe of human proteins at neXtProt for SLC25A2: NX_Q9BXI2

Explore proteomics data for SLC25A2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SLC25A2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_114153.1  
    ENSEMBL proteins: 
     ENSP00000239451  
    Reactome Protein details: Q9BXI2

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Mitochondrial ornithine transporter 2
    Mitochondrial ornithine transporters

    2 InterPro protein domains:
     IPR023395 Mt_carrier_dom
     IPR018108 Mitochondrial_sb/sol_carrier

    Graphical View of Domain Structure for InterPro Entry Q9BXI2

    ProtoNet protein and cluster: Q9BXI2

    UniProtKB/Swiss-Prot: ORNT2_HUMAN, Q9BXI2
    Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family
    Similarity: Contains 3 Solcar repeats


    Find genes that share domains with SLC25A2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ORNT2_HUMAN, Q9BXI2
    Function: Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000064L-ornithine transmembrane transporter activity ----
         
    Find genes that share ontologies with SLC25A2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SLC25A2:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC25A2
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC25A2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SLC25A2

    miRNA
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    miRTarBase miRNAs that target SLC25A2:
    hsa-mir-378a-3p (MIRT043873)

    Block miRNA regulation of human, mouse, rat SLC25A2 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate SLC25A2:
    hsa-miR-491-3p
    SwitchGear 3'UTR luciferase reporter plasmidSLC25A2 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC25A2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ORNT2_HUMAN, Q9BXI2: Mitochondrion inner membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytosol2
    endoplasmic reticulum1
    extracellular1
    nucleus1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane TAS--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with SLC25A2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SLC25A2 About    
    See pathways by source

    SuperPathContained pathways About
    1Metabolism of amino acids and derivatives
    Metabolism of amino acids and derivatives
    Urea cycle0.00
    2Metabolism
    Metabolism0.38


    Find genes that share SuperPaths with SLC25A2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for SLC25A2
        Urea cycle


        Pathway & Disease-focused RT2 Profiler PCR Array including SLC25A2: 
              Mitochondria in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for SLC25A2

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for SLC25A2 (ENSP000002394514) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ASS1ENSP000002530044STRING: ENSP00000253004
    OTCENSP000000390074STRING: ENSP00000039007
    SIAH1ENSP000003491564STRING: ENSP00000349156
    SIAH2ENSP000003224574STRING: ENSP00000322457
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000050urea cycle TAS--
    GO:0000066mitochondrial ornithine transport ----
    GO:0006810transport IEA--
    GO:0034641cellular nitrogen compound metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    Find genes that share ontologies with SLC25A2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC25A2 (ORNT2)

    1 HMDB Compound for SLC25A2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Ornithine(+)-S-Ornithine (see all 9)70-26-8--

    1 DrugBank Compound for SLC25A2    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    L-Ornithine(S)-2,5-Diaminopentanoate (see all 4)70-26-8target--16940241 11997094 12948741



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SLC25A2 gene: 
    NM_031947.2  

    Unigene Cluster for SLC25A2:

    Solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2
    Hs.97647  [show with all ESTs]
    Unigene Representative Sequence: NM_031947
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000239451(uc003ljf.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SLC25A2 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate SLC25A2:
    hsa-miR-491-3p
    SwitchGear 3'UTR luciferase reporter plasmidSLC25A2 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat SLC25A2
      QuantiFast Probe-based Assays in human, mouse, rat SLC25A2

    Additional mRNA sequence: 

    AF332005.1 AF378119.1 AY208943.1 BC069458.1 BC100935.2 BC100936.1 BC100937.2 

    1 DOTS entry:

    DT.65284550 

    11 AceView cDNA sequences:

    AF332005 NM_031947 AY208943 BX118364 AI200784 AF378119 AA398593 AI208615 
    BC069458 AA719056 AA393441 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC25A2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SLC25A2 Expression
    About this image


    SLC25A2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Neural Tube (Nervous System)
             Metencephalon
     
     Brain (Nervous System)
             Medulla Oblongata
     
     Testis (Reproductive System)
    SLC25A2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC25A2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.97647

    UniProtKB/Swiss-Prot: ORNT2_HUMAN, Q9BXI2
    Tissue specificity: Expressed in liver, kidney, pancreas and cultured fibroblasts

        Pathway & Disease-focused RT2 Profiler PCR Array including SLC25A2: 
              Mitochondria in human mouse rat

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC25A2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc25a25 solute carrier family 25 (mitochondrial carrier, ornithine more   --   18 (19.54 cM) 37637378 
    chicken
    (Gallus gallus)
    Aves SLC25A156
    Gallus gallus solute carrier family 25 (mitochondr...
    75(a)
    1 → many
    1(169805866-169821444)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    75(a)
    1 → many
    1(132584192-132595501)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia MGC1084501 MGC108450 protein 74.22(n)
    74.33(a)
      548517  NM_001015800.1  NP_001015800.1 
    zebrafish
    (Danio rerio)
    Actinopterygii slc25a15b6
    solute carrier family 25 (mitochondrial carrier; o...
    61(a)
    many ↔ many
    5(25825105-25832507) ENSDARG00000062271
    fruit fly
    (Drosophila melanogaster)
    Insecta CG16286
    --
    31(a)
    1 → many
    X(10492179-10496747)
    worm
    (Caenorhabditis elegans)
    Secernentea T10F2.26
    Protein T10F2.2 (T10F2.2) mRNA, complete cds
    45(a)
    1 → many
    III(5163755-5165313) WBGene00020422
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ORT16
    Ornithine transporter of the mitochondrial inner m...
    30(a)
    1 → many
    XV(569929-570807) YOR130C


    ENSEMBL Gene Tree for SLC25A2 (if available)
    TreeFam Gene Tree for SLC25A2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC25A2 gene
    SLC25A152  
    5 SIMAP similar genes for SLC25A2 using alignment to 1 protein entry:     ORNT2_HUMAN:
    SLC25A15    SLC25A20    SLC25A45    SLC25A48    SLC25A29

    Find genes that share paralogs with SLC25A2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Polymorphic Variants from UniProtKB/Swiss-Prot
    ORNT2_HUMAN, Q9BXI2: Variant Cys-159 has a reduced ornithine transport activity, while variant Gly-181 has an increased
    activity


    Selected SNPs for SLC25A2 (see all 97)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1112928131,2
    C,F--140681697(+) CCACAT/AGAAGA 1 -- ds50012Minor allele frequency- A:0.50NA CSA 4
    rs569764841,2
    C,F--140681735(+) AGTGCG/ACATGT 1 -- ds50016Minor allele frequency- A:0.15WA CSA NA EA 363
    rs1927768751,2
    --140681834(+) CTGAGA/GTCAGG 1 -- ds50010--------
    rs1436975331,2
    --140681916(+) GTGGCA/GGGCAC 1 -- ds50010--------
    rs1124280821,2
    C,F--140681962(+) GAATCG/ACTTGA 1 -- ds50011Minor allele frequency- A:0.50NA 2
    rs1509734441,2
    --140681983(+) CAGAGG/TTTGCA 1 -- ds50010--------
    rs1408384031,2
    C--140682212(+) ACAAAC/TGGCTT 1 -- ut310--------
    rs1501599461,2
    C--140682239(+) CAGAAC/TGATAT 1 -- ut310--------
    rs1386330141,2
    C--140682311(+) AAGAGC/TAGCAA 1 -- ut310--------
    rs1893626951,2
    --140682405(+) AGAAGA/GGAAGA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SLC25A2 (140682196 - 140683612 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SLC25A2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv428127CNV Loss18775914
    dgv1858e1CNV Complex17122850
    dgv1857e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC25A2
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC25A2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608157    OMIM disorders: --

    2 diseases for SLC25A2:    
    About MalaCards
    urea cycle disorder    ornithine translocase deficiency

    1 disease from the University of Copenhagen DISEASES database for SLC25A2:
    Ornithine translocase deficiency

    Find genes that share disorders with SLC25A2           About GenesLikeMe

    Genetic Association Database (GAD): SLC25A2
    Human Genome Epidemiology (HuGE) Navigator: SLC25A2 (2 documents)

    Export disorders for SLC25A2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC25A2 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with SLC25A2)
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    1. Cloning and characterization of human ORNT2: a second mitochondrial ornithine transporter that can rescue a defective ORNT1 in patients with the hyperornithinemia-hyperammonemia-homocitrullinuria syndrome, a urea cycle disorder. (PubMed id 12948741)1, 2, 7 Camacho J.A. III... Kong J. (Mol. Genet. Metab. 2003)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PubMed id 19240061)1, 4 Trynka G....Wijmenga C. (Gut 2009)
    4. Comparative DNA sequence analysis of mouse and human protocadherin gene clusters. (PubMed id 11230163)1, 2 Wu Q.... Maniatis T. (Genome Res. 2001)
    5. Mammalian mitochondrial inner membrane cationic and neutral amino acid carriers. (PubMed id 11004451)1, 3 Porter R.K. (Biochim. Biophys. Acta 2000)
    6. The mitochondrial transporter family SLC25: identification, properties and physiopathology. (PubMed id 23266187)1 Palmieri F. (Mol. Aspects Med. 2013)
    7. Substrate specificity of the two mitochondrial ornithine carriers can be swapped by single mutation in substrate binding site. (PubMed id 22262851)1 MonnAc M....Palmieri F. (J. Biol. Chem. 2012)
    8. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    9. Clinical and functional characterization of a human ORNT1 mutation (T32R) in the hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome. (PubMed id 16940241)7 Camacho J.A....Cederbaum S.D. (Pediatr. Res. 2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 83884 HGNC: 22921 AceView: SLC25A2 Ensembl:ENSG00000120329 euGenes: HUgn83884
    ECgene: SLC25A2 H-InvDB: SLC25A2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SLC25A2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SLC25A2 gene:
    Search GeneIP for patents involving SLC25A2

    GeneCards and IP:
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