POLR2D Gene
protein-coding GIFtS: 60
GCID: GC02M128637
|
|
polymerase (RNA) II (DNA directed) polypeptide D
| |
Aliases
for POLR2D gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Polymerase (RNA) II (DNA Directed) Polypeptide D1 2 | | HSRBP42 | | RBP41 2 | | HSRPB42 | | RPB162 3 | | DNA-Directed RNA Polymerase II 16 KDa Polypeptide2 | | DNA-Directed RNA Polymerase II Subunit D2 3 | | DNA-Directed RNA Polymerase II Subunit RPB42 | | RNA Polymerase II 16 KDa Subunit2 3 | | RNA Polymerase II Subunit HsRBP42 | | RNA Polymerase II Subunit B42 3 | | |
Export aliases for POLR2D gene to outside databasesPrevious GC identifers: GC02M125901 GC02M126528 GC02M128509 GC02M128697 GC02M128320 GC02M128606 GC02M120910 GC02M128608 GC02M128620 |
Summaries
for POLR2D gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for POLR2D:
This gene encodes the fourth largest subunit of RNA polymerase II, the polymerase responsible for synthesizingmessenger RNA in eukaryotes. In yeast, this polymerase subunit is associated with the polymerase under suboptimalgrowth conditions and may have a stress protective role. A sequence for a ribosomal pseudogene is contained within the3' untranslated region of the transcript from this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: RPB4_HUMAN, O15514Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleosidetriphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functionalnon-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It iscomposed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to apocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock theclamp via RPB7 in the closed conformation thus preventing double stranded DNA to enter the active site cleft. TheRPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity)
Gene Wiki entry for POLR2D (RNA polymerase II subunit B4)
|
Genomic Views
for POLR2D gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022135.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the POLR2D gene promoter:
SRF HOXA9 HOXA9B CUTL1 Meis-1b POU2F1 POU2F1a ZIC2/Zic2 Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for POLR2D
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POLR2D |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q21 Ensembl cytogenetic band: 2q14.3 HGNC cytogenetic band: 2q21POLR2D Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M128637: view genomic region
(about GC identifiers)
Start:
|
128,603,840 bp from pter |
End:
|
128,615,731 bp from pter |
Size:
|
11,892 bases |
Orientation:
|
minus strand |
|
Proteins
for POLR2D gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RPB4_HUMAN, O15514 (See
protein sequence)Recommended Name: DNA-directed RNA polymerase II subunit RPB4 Size: 142 amino acids; 16311 Da
Subunit: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplexthat protrudes from the 10-subunit Pol II core complex
Subcellular location: Nucleus
1 PDB 3D structure from  and Proteopedia  for POLR2D:2C35 (3D)
Secondary accessions: Q52LT4Explore the universe of human proteins at neXtProt for POLR2D: NX_O15514
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O15514
POLR2D Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004796.1
ENSEMBL proteins: ENSP00000272645 ENSP00000387323 ENSP00000387117 Reactome Protein details: O15514
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
POLR2D for ontologies About GeneDecksing
POLR2D Antibody Products:
Assay Products for POLR2D: |
Protein
Domains /
Families
for POLR2D gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
POLR2D for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O15514ProtoNet protein and cluster: O15514 1 Blocks protein family: IPB005574 RNA polymerase Rpb4
UniProtKB/Swiss-Prot: RPB4_HUMAN, O15514Similarity: Belongs to the eukaryotic RPB4 RNA polymerase subunit family |
Function
for POLR2D gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RPB4_HUMAN, O15514Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleosidetriphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functionalnon-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It iscomposed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to apocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock theclamp via RPB7 in the closed conformation thus preventing double stranded DNA to enter the active site cleft. TheRPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity) Genatlas biochemistry entry for POLR2D:polymerase II,RNA DNA directed,polypeptide D likely associating with POLR2G (RPB7)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2D (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2D
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: POLR2D (NM_004805) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for POLR2D | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLR2D |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLR2D |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
POLR2D for ontologies About GeneDecksing
5 GenomeRNAi human phenotypes for POLR2D:
|
Pathways & Interactions
for POLR2D gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/15 super-pathways (see all 15) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Formation of RNA Pol II elongation complex | | | 2 | mRNA Splicing - Major Pathway | | | 3 | HIV Infection | | | 4 | Nucleotide Excision Repair | | | 5 | Late Phase of HIV Life Cycle | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 EMD Millipore Pathways for POLR2D
2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for POLR2D
3  GeneGo (Thomson Reuters) Pathways for POLR2D
5/49 
Reactome Pathways for POLR2D (see all 49)
5 
Kegg Pathways (Kegg details for POLR2D):
POLR2D for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for POLR2D
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/229 Interacting proteins for POLR2D (O155143 ENSP000002726454) via UniProtKB, MINT, STRING, and/or I2D (see all 229)About this table
Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000398 | mRNA splicing, via spliceosome |
TAS | -- | | GO:0006281 | DNA repair |
TAS | -- | | GO:0006283 | transcription-coupled nucleotide-excision repair |
TAS | -- | | GO:0006289 | nucleotide-excision repair |
TAS | -- | | GO:0006366 | transcription from RNA polymerase II promoter |
TAS | -- |
POLR2D for ontologies About GeneDecksing
|
Drugs & Compounds
for POLR2D gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for POLR2D
Search CenterWatch for drugs/clinical trials and news about POLR2D / RPB4
|
Transcripts
for POLR2D gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for POLR2D gene: NM_004805.3 Unigene Cluster for POLR2D: Polymerase (RNA) II (DNA directed) polypeptide D Hs.715348 [show with all ESTs]Unigene Representative Sequence: NM_0048054 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000272645(uc002tpj.3) ENST00000409955 ENST00000487079 ENST00000409698
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2D (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2D
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: POLR2D (NM_004805) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for POLR2D | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLR2D |
Additional cDNA sequence: BC002958.1 BC010427.1 BC017205.2 BC093795.1 BC093797.1 U85510.1 12 DOTS entries: DT.446111 DT.97792648 DT.100770146 DT.100789719 DT.95114967 DT.86847479 DT.100789710 DT.91947081 DT.97796174 DT.97858907 DT.100789714 DT.100789715 24/209 AceView cDNA sequences (see all 209): BG435027 CB161125 CD109965 CA489835 CR590602 AI292051 BQ921030 BC017205 BM554236 NM_004805 BC010427 CA424341 AI538216 AW576292 AL581133 CA437991 U85510 BQ674819 AA312579 CA430646 AW246687 AA598900 CA426573 CB119029
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for POLR2D (see all 6) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e |
|---|
|
| SP1: | | | - | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | - | | - | | - | | | | | | | | | | | | | | |
| SP4: | | | - | | | | - | | - | | | | | | | | | | | | |
| SP5: | | | - | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for POLR2D
|
Expression
for POLR2D gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| POLR2D expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACCTCCACCA
About this image
See POLR2D Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for POLR2D
SOURCE GeneReport for Unigene cluster: Hs.715348
SABiosciences Custom PCR Arrays for POLR2D
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for POLR2D
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat POLR2D | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POLR2D | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POLR2D | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLR2D |
Orthologs
for POLR2D gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for POLR2D gene from 9/29 species (see all 29) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Polr2d1 , 5 |
polymerase (RNA) II (DNA directed) polypeptide D1, 5 |
87.56(n)1
100(a)1 |
|
18 (17.85 cM)5
692411 NM_027002.31 NP_081278.11
317891595 |
chicken
(Gallus gallus) |
Aves |
POLR2D1 |
polymerase (RNA) II (DNA directed) polypeptide D |
83.1(n)
97.18(a) |
|
424754 XM_422576.3 XP_422576.2 |
lizard
(Anolis carolinensis) |
Reptilia |
POLR2D6 |
-- |
96(a) |
1 ↔ 1 |
3(36329397-36335722) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.80562 |
Xenopus laevis transcribed sequence with moderate similarity more |
79.23(n) |
|
CB942419.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
570843982 |
-- |
77.92(n) |
|
57084398 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Rpb46 |
-- |
73(a) |
1 ↔ 1 |
3R(14078565-14081191) |
worm
(Caenorhabditis elegans) |
Secernentea |
F43E2.23
rpb-41 |
Protein RPB-41 |
57(a)3
57.86(n)1
58.57(a)1 |
|
II(7371817-7372676)3
1742081 NM_063143.31 NP_495544.21 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
NRPB41 |
DNA-directed RNA polymerase II subunit D |
50.25(n)
40.15(a) |
|
830853 NM_121029.2 NP_196554.1 |
rice
(Oryza sativa) |
Liliopsida |
Os02g01169001 |
hypothetical protein |
49.75(n)
41.67(a) |
|
4328083 NM_001052218.1 NP_001045683.1 |
ENSEMBL Gene Tree for POLR2D (if available)
TreeFam Gene Tree for POLR2D (if available) |
Paralogs
for POLR2D gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for POLR2D gene
POLR2D for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for POLR2D
PGOHUM00000240870 PGOHUM00000233534
|
Genomic Variants
for POLR2D gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for POLR2D (128603840 - 128615731 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for POLR2D: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing POLR2D |
|
Disorders
/ Diseases
for POLR2D gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
POLR2D for disorders About GeneDecksing
OMIM gene information: 606017
OMIM disorders: --
15  diseases for POLR2D: About MalaCardsretinol binding protein type 2 diabetes mellitus fatty liver disease esophageal squamous cell carcinoma
squamous cell carcinoma diabetes mellitus insulin resistance liver disease
huntington's disease conjunctivitis esophagitis carcinoma
immunodeficiency malaria alcoholism
Human Genome Epidemiology (HuGE) Navigator: POLR2D (1 document)
Export disorders for POLR2D gene to outside databases
|
Publications
for POLR2D gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for POLR2D gene, integrated from 9 sources (see all 110):
(articles sorted by number of sources associating them with POLR2D) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Analysis of the interaction of the novel RNA polymerase II (pol II) subunit hsRPB4 with its partner hsRPB7 and with pol II. (PubMed id 9528765)1, 2, 3 Khazak V....Golemis E.A. (1998)
- Crystal structure and RNA binding of the Rpb4/Rpb7 subunits of human RNA polymerase II. (PubMed id 16282592)1, 2 Meka H.... Brick P. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes. (PubMed id 9852112)1, 2 Kershnar E.... Chiang C.-M. (1998)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- Deployment of the human immunodeficiency virus type 1 protein arsenal: combating the host to enhance viral transcription and providing targets for therapeutic development. (PubMed id 22422068)1 Dahiya S....Wigdahl B. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- New insights into the control of HIV-1 transcription: when Tat meets the 7SK snRNP and super elongation complex (SEC). (PubMed id 21360054)1 He N. and Zhou Q. (2011)
|
External Searches for POLR2D gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing POLR2D gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing POLR2D gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing POLR2D gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for POLR2D gene:
Search GeneIP for patents involving POLR2D
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for POLR2D gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for POLR2D | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for POLR2D | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for POLR2D | | | OriGene Protein Over-expression Lysate for POLR2D | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for POLR2D | | OriGene 3'-UTR Clone for POLR2D | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2D | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for POLR2D | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for POLR2D | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for POLR2D | | OriGene Custom Protein Services for POLR2D | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat POLR2D | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing POLR2D | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat POLR2D | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat POLR2D | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat POLR2D | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat POLR2D |
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| | | | Search Tocris compounds for POLR2D |
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 | | | POLR2D Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for POLR2D |
|  |  |  | | | | Search ThermoFisher Antibodies for POLR2D |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat POLR2D |
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