MTHFS Gene
protein-coding GIFtS: 59
GCID: GC15M080125
|
|
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate...
| |
Aliases
for MTHFS gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| 5,10-Methenyltetrahydrofolate Synthetase (5-FormyltetrahydrofolateCyclo-Ligase)1 2 | | HsT192681 2 | | Methenyl-THF Synthetase2 3 | | 5-Formyltetrahydrofolate Cyclo-Ligase2 | | 5,10-Methenyl-Tetrahydrofolate Synthetase3 | | EC 6.3.3.23 |
Export aliases for MTHFS gene to outside databasesPrevious GC identifers: GC15M076098 GC15M073294 GC15M077713 GC15M077853 GC15M077924 GC15M080137 GC15M056895 |
Summaries
for MTHFS gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MTHFS:
The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activityof the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variantsencoding two different isoforms have been found for this gene. (provided by RefSeq, Jun 2011)
UniProtKB/Swiss-Prot: MTHFS_HUMAN, P49914Function: Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependentone-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids
|
Genomic Views
for MTHFS gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MTHFS gene promoter:
POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) Cdc5 POU3F2 Gfi-1 CREB c-Rel POU2F1 deltaCREB POU2F1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for MTHFS
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MTHFS |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q25.1 Ensembl cytogenetic band: 15q25.1 HGNC cytogenetic band: 15q24.3MTHFS Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M080125: view genomic region
(about GC identifiers)
Start:
|
80,125,927 bp from pter |
End:
|
80,189,721 bp from pter |
Size:
|
63,795 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr15- 80,137,537-80,216,096 |
|
Proteins
for MTHFS gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MTHFS_HUMAN, P49914 (See
protein sequence)Recommended Name: 5-formyltetrahydrofolate cyclo-ligase Size: 203 amino acids; 23256 Da
Cofactor: Magnesium
Subunit: Monomer
Subcellular location: Cytoplasm
4 PDB 3D structures from  and Proteopedia  for MTHFS:3HXT (3D)
3HY3 (3D)
3HY4 (3D)
3HY6 (3D)
Explore the universe of human proteins at neXtProt for MTHFS: NX_P49914
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P49914
MTHFS Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001186687.1 NP_006432.1
ENSEMBL proteins: ENSP00000454318 ENSP00000258874 ENSP00000454626
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
MTHFS for ontologies About GeneDecksing
MTHFS Antibody Products:
Assay Products for MTHFS: |
Protein
Domains /
Families
for MTHFS gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MTHFS for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P49914ProtoNet protein and cluster: P49914 1 Blocks protein family: IPB002698 5-formyltetrahydrofolate cyclo-ligase
UniProtKB/Swiss-Prot: MTHFS_HUMAN, P49914Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family |
Function
for MTHFS gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MTHFS_HUMAN, P49914Function: Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependentone-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acidsCatalytic activity: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate Genatlas biochemistry entry for MTHFS:5,10-methenyl tetrahydrofolate (THF) synthetase,preferentially expressed in the liver,5-formyltetrahydrofolatecyclo-ligase,catalyzing the obligatory initial metabolic step,in the inctracellular conversion of 5-formyl THF toother reduced folates
Enzyme Number (IUBMB): EC 6.3.3.21
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MTHFS (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for MTHFS | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MTHFS |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTHFS |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
MTHFS for ontologies About GeneDecksing
Animal Models:
5 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Mthfs):
MTHFS for phenotypes About GeneDecksing
|
Pathways & Interactions
for MTHFS gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Antimetabolite Pathway - Folate Cycle, Pharmacodynamics | | | 2 | One Carbon Metabolism | | | 3 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for MTHFS
3  PharmGKB Pathways for MTHFS
2 
Kegg Pathways (Kegg details for MTHFS):
MTHFS for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MTHFS
STRING Interaction
Network Preview (showing 5 interactants - click image to see 9)
5/9 Interacting proteins for MTHFS (P499143 ENSP000002588744) via UniProtKB, MINT, STRING, and/or I2D (see all 9)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
MTHFS for ontologies About GeneDecksing
|
Drugs & Compounds
for MTHFS gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MTHFS for compounds About GeneDecksing
 Browse Tocris compounds for MTHFS
7 HMDB Compounds for MTHFS About this table
5 Novoseek chemical compound relationships for MTHFS gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| 5,10-methenyltetrahydrofolate |
98.2 |
26 |
16104022 (3), 15135403 (2), 19022216 (2), 19738041 (2) (see all 15) |
| leucovorin |
76.7 |
13 |
16365037 (2), 9030524 (2), 15135403 (1), 8522195 (1) (see all 7) |
| folate |
66.3 |
7 |
7766710 (2), 15135403 (1), 19738041 (1), 16365037 (1) (see all 5) |
| 5-methyltetrahydrofolate |
65.5 |
1 |
11520899 (1) |
| atp |
26.4 |
4 |
16104022 (1), 7766710 (1) |
Search CenterWatch for drugs/clinical trials and news about MTHFS
|
Transcripts
for MTHFS gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MTHFS gene (2 alternative transcripts): NM_001199758.1 NM_006441.3 Unigene Clusters for MTHFS: 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) Hs.194294 [show with all ESTs], Hs.459049 [show with all ESTs]Unigene Representative Sequences: AL109717, NR_0376544 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000560261 ENST00000258874(uc021srp.1 uc002bex.4 uc021srq.1 uc021srr.1)
ENST00000560919 ENST00000559722
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MTHFS (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MTHFS (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): MTHFS (NM_006441) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MTHFS | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MTHFS |
Additional cDNA sequence: AL110101.1 BC012417.1 BC019921.1 L38928.1 NR_037654.1 12 DOTS entries: DT.117581 DT.87016173 DT.209667 DT.92456944 DT.100027654 DT.100749995 DT.437088 DT.97788429 DT.91869599 DT.92456953 DT.80100252 DT.86996839 24/307 AceView cDNA sequences (see all 307): BM674537 BU077484 BM510737 BM769396 AI090295 BM450865 R14575 BM830783 AL109714 AI188428 AI420454 AA701992 BM830804 BM823153 BM507216 AA765734 BM823582 BQ938159 CK905549 BM769301 AW273775 AA807026 AI160812 BM508087
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for MTHFS About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b |
|---|
|
| SP1: | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | - | | | | | | |
| SP3: | | | | | | | | | - | | | | | |
ECgene alternative splicing isoforms for MTHFS
|
Expression
for MTHFS gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MTHFS expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAGGTAGATG
About this image
See MTHFS Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MTHFS
SOURCE GeneReport for Unigene clusters: Hs.194294 Hs.459049
SABiosciences Custom PCR Arrays for MTHFS
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MTHFS
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTHFS |
Orthologs
for MTHFS gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for MTHFS gene from 10/34 species (see all 34) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
MTHFS1 |
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate more |
71.07(n)
70.56(a) |
|
415484 XM_413857.3 XP_413857.2 |
lizard
(Anolis carolinensis) |
Reptilia |
MTHFS6 |
-- |
67(a) |
1 → many |
GL343332.1(424653-438210) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.172552 |
Xenopus laevis transcribed sequence with weak similarity more |
74.03(n) |
|
CA974461.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.167182 |
Transcribed sequence with weak similarity to protein more |
73.95(n) |
|
BI980761.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG110793
CG344241 |
5-formyltetrahydrofolate cyclo-ligase3
CG344241 |
35(a)3
49.48(n)1
38.14(a)1 |
|
59D83
376991 NM_001103962.21 NP_001097432.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
Y106G6E.43
CELE_Y106G6E.41 |
5-formyltetrahydrofolate cyclo-ligase3
Protein Y106G6E.41 |
38(a)3
44.27(n)1
38.97(a)1 |
|
I(10229739-10230891)3
1909221 NM_060291.41 NP_492692.11 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
FAU1(YER183C)4
FAU11 |
5,10-methenyltetrahydrofolate synthetase, involved more4
Fau1p1 |
44.44(n)1
32.28(a)1 |
|
5(553969-553334)4
8569321, 4 NP_011110.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
5-FCL1 |
5-formyltetrahydrofolate cycloligase |
46.74(n)
32.8(a) |
|
831144 NM_121308.2 NP_568284.1 |
rice
(Oryza sativa) |
Liliopsida |
Os07g05786001 |
hypothetical protein |
46.18(n)
35.42(a) |
|
4343714 NM_001066630.1 NP_001060095.1 |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
fau6 |
conserved protein, 5-formyltetrahydrofolate cyclo-... |
21(a) |
1 → many |
Chromosome(3054263-3054811) |
ENSEMBL Gene Tree for MTHFS (if available)
TreeFam Gene Tree for MTHFS (if available) |
Paralogs
for MTHFS gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MTHFS gene
- ST20-MTHFS2
MTHFS for paralogs About GeneDecksing
|
Genomic Variants
for MTHFS gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MTHFS (80125927 - 80189721 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for MTHFS
1 CNV: 87763
1 Indel: 87762
Human Gene Mutation Database (HGMD): MTHFS
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MTHFS |
|
Disorders
/ Diseases
for MTHFS gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MTHFS for disorders About GeneDecksing
OMIM gene information: 604197
OMIM disorders: --
17  diseases for MTHFS: About MalaCardsdiffuse large b-cell lymphoma b-cell lymphomas non-hodgkin lymphoma spina bifida
hodgkin's lymphoma follicular lymphoma keratoconus cataract
homocysteine ovarian carcinoma ovarian cancer colorectal cancer
lung cancer atherosclerosis pneumonia neuroblastoma
carcinoma
Human Genome Epidemiology (HuGE) Navigator: MTHFS (15 documents)
Export disorders for MTHFS gene to outside databases
|
Publications
for MTHFS gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MTHFS gene, integrated from 9 sources (see all 38):
(articles sorted by number of sources associating them with MTHFS) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and characterization of the human 5,10- methenyltetrahydrofolate synthetase-encoding cDNA. (PubMed id 8522195)1, 2, 3, 9 Dayan A.... Jolivet J. (1995)
- Structural basis for the inhibition of human 5,10- methenyltetrahydrofolate synthetase by N10-substituted folate analogues. (PubMed id 19738041)1, 2, 9 Wu D....Liu Z.-J. (2009)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Human liver methenyltetrahydrofolate synthetase: improved purification and increased affinity for folate polyglutamate substrates. (PubMed id 3801490)1, 2 Bertrand R.... Jolivet J. (1987)
- Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies. (PubMed id 18522750)1, 9 Kottgen A....Fox C.S. (2008)
- One-carbon metabolism gene polymorphisms and risk of non-Hodgkin lymphoma in Australia. (PubMed id 17891500)1, 9 Lee K.M....Armstrong B.K. (2007)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
- The impact of 5,10-methenyltetrahydrofolate synthetase polymorphism on diabetic nephropathy in the Taiwanese population. (PubMed id 21895484)1 Lin C.J....Hsieh C.H. (2012)
- A data set of human endogenous protein ubiquitination sites. (PubMed id 20972266)1 Shi Y....Qin J. (2011)
|
External Searches for MTHFS gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MTHFS gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MTHFS gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MTHFS gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MTHFS | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MTHFS gene:
Search GeneIP for patents involving MTHFS
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MTHFS gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for MTHFS | | OriGene shRNA RFP for MTHFS | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MTHFS | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MTHFS | | | OriGene Protein Over-expression Lysate for MTHFS | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MTHFS | | OriGene 3'-UTR Clone for MTHFS | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MTHFS | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MTHFS | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MTHFS | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MTHFS | | OriGene Custom Protein Services for MTHFS | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MTHFS | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MTHFS | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MTHFS | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MTHFS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MTHFS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MTHFS |
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| | | | Search Tocris compounds for MTHFS |
| |  |  |  |  | | | | | | Recombinant Protein for MTHFS |
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 | | | MTHFS Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTHFS |
|  |  |  | | | | ThermoFisher Antibodies for MTHFS |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MTHFS |
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