Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



MT1M Gene

protein-coding   GIFtS: 47
GCID: GC16P056666

Metallothionein 1M

(Previous name: metallothionein 1K)
(Previous symbols: MT1, MT1K)
  Search for MT1M
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Metallothionein 1M1 2     MT-IM2 3
MT1K1 2 3 5     Metallothionein 1Y2
MT11 2     metallothionein-1M2
Metallothionein 1K1 2     Metallothionein-IM3
MT-1M2 3     

External Ids:    HGNC: 142961   Entrez Gene: 44992   Ensembl: ENSG000002053647   OMIM: 1563575   UniProtKB: Q8N3393   

Export aliases for MT1M gene to outside databases

Previous GC identifers: GC16P055225 GC16P042535


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for MT1M Gene:
This gene encodes a member of the metallothionein superfamily, type 1 family. Metallothioneins have a high content
of cysteine residues that bind various heavy metals. These genes are transcriptionally regulated by both heavy
metals and glucocorticoids. (provided by RefSeq, Oct 2011)

GeneCards Summary for MT1M Gene:
MT1M (metallothionein 1M) is a protein-coding gene. An important paralog of this gene is MT1G.

UniProtKB/Swiss-Prot: MT1M_HUMAN, Q8N339
Function: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins
are transcriptionally regulated by both heavy metals and glucocorticoids

Gene Wiki entry for MT1M Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000016.10  NC_018927.2  NT_010498.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the MT1M gene promoter:
         TBP   p53   Sp1   Zic1   TFIID   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for MT1M

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MT1M


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q13   Ensembl cytogenetic band:  16q12.2   HGNC cytogenetic band: 16q13

MT1M Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MT1M gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P056666:  view genomic region     (about GC identifiers)

Start:
56,666,145 bp from pter      End:
56,667,898 bp from pter
Size:
1,754 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: MT1M_HUMAN, Q8N339 (See protein sequence)
Recommended Name: Metallothionein-1M  
Size: 61 amino acids; 6110 Da
Subunit: Monomer (By similarity)
Secondary accessions: Q8TDN3

Explore the universe of human proteins at neXtProt for MT1M: NX_Q8N339

Explore proteomics data for MT1M at MOPED


See MT1M Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_789846.1  
ENSEMBL proteins: 
 ENSP00000369146   ENSP00000457575  

MT1M Human Recombinant Protein Products:

Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
OriGene Protein Over-expression Lysate for MT1M
OriGene Custom MassSpec
OriGene Custom Protein Services for MT1M
GenScript Custom Purified and Recombinant Proteins Services for MT1M
Novus Biologicals MT1M Protein
Novus Biologicals MT1M Lysate
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for MT1M

 
Search eBioscience for Proteins for MT1M 

MT1M Antibody Products:

Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for MT1M
Search for Antibodies for MT1M at Abcam
Cloud-Clone Corp. Antibodies for MT1M
Search ThermoFisher Antibodies for MT1M
Search LSBio for Antibodies for MT1M

MT1M Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for MT1M
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for MT1M
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for MT1M
Cloud-Clone Corp. CLIAs for MT1M
Search eBioscience for ELISAs for MT1M 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus
HGNC Gene Families:
MT: Metallothioneins

5 InterPro protein domains:
 IPR000006 Metalthion_vert
 IPR018064 Metalthion_vert_metal_BS
 IPR003019 Metalthion_sfam_euk
 IPR023587 Metalthion_dom_vert
 IPR017854 Metalthion_dom

Graphical View of Domain Structure for InterPro Entry Q8N339

ProtoNet protein and cluster: Q8N339

1 Blocks protein domain: IPB002400 Growth factor cystine knot superfamily signature

UniProtKB/Swiss-Prot: MT1M_HUMAN, Q8N339
Domain: Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A
of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the
corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines
Similarity: Belongs to the metallothionein superfamily. Type 1 family


Find genes that share domains with MT1M           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Molecular Function:

     UniProtKB/Swiss-Prot Summary: MT1M_HUMAN, Q8N339
Function: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins
are transcriptionally regulated by both heavy metals and glucocorticoids

     Gene Ontology (GO): 2 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008270zinc ion binding ISS--
GO:0046872metal ion binding ----
     
Find genes that share ontologies with MT1M           About GenesLikeMe


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MT1M
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MT1M

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MT1M
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MT1M

miRNA
Products:
    
miRTarBase miRNAs that target MT1M:
hsa-mir-26b-5p (MIRT028853)

Block miRNA regulation of human, mouse, rat MT1M using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate MT1M
SwitchGear 3'UTR luciferase reporter plasmidMT1M 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for MT1M
Predesigned siRNA for gene silencing in human, mouse, rat MT1M

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for MT1M

Clone
Products:
     
OriGene clones in human, mouse for MT1M (see all 5)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: MT1M (NM_176870)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for MT1M
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MT1M

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for MT1M
Browse ESI BIO Cell Lines and PureStem Progenitors for MT1M 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MT1M


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus4
extracellular3
cytosol1

Gene Ontology (GO): 3 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus ISS--
GO:0005737cytoplasm ISS--
GO:0048471perinuclear region of cytoplasm ISS--

Find genes that share ontologies with MT1M           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus

SuperPaths for MT1M About    
See pathways by source

SuperPathContained pathways About
1Mineral absorption
Mineral absorption


Find genes that share SuperPaths with MT1M           About GenesLikeMe

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways



1 Kegg Pathway  (Kegg details for MT1M):
    Mineral absorption

    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MT1M
Interactions:

    Search GeneGlobe Interaction Network for MT1M

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for MT1M (ENSP000003691464) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
RELBENSP000002214524STRING: ENSP00000221452
About this table

Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0045926negative regulation of growth ISS--
GO:0071294cellular response to zinc ion ISS--

Find genes that share ontologies with MT1M           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus
Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for MT1M

1 HMDB Compound for MT1M    About this table
CompoundSynonyms CAS #PubMed Ids
CadmiumCd (see all 6)7440-43-9--



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
About This Section

TryGeneCards Plus

REFSEQ mRNAs for MT1M gene: 
NM_176870.2  

Unigene Cluster for MT1M:

Metallothionein 1M
Hs.647370  [show with all ESTs]
Unigene Representative Sequence: BI488702
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000379818(uc010vhe.2 uc002ejn.3) ENST00000570233
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat MT1M using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate MT1M
SwitchGear 3'UTR luciferase reporter plasmidMT1M 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for MT1M
Predesigned siRNA for gene silencing in human, mouse, rat MT1M
Clone
Products:
     
OriGene clones in human, mouse for MT1M (see all 5)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: MT1M (NM_176870)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for MT1M
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MT1M
Primer
Products:
    
OriGene qPCR primer pairs and template standards for MT1M
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat MT1M
  QuantiTect SYBR Green Assays in human, mouse, rat MT1M
  QuantiFast Probe-based Assays in human, mouse, rat MT1M

Additional mRNA sequence: 

AF136177.1 BC028280.1 BC103841.1 

6 DOTS entries:

DT.87013327  DT.100746942  DT.219306  DT.120684849  DT.92419270  DT.95167555 

21 AceView cDNA sequences:

BC069421 BX118979 H72723 NM_005947 BC028280 AI719425 BF973961 AA370427 
AY168638 NM_176870 BU663337 BG217075 R99207 AF349000 H72722 BG183187 
BG192094 BG221550 R99208 BG220590 BG195149 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

MT1M expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
MT1M Expression
About this image


MT1M expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 5) fully expand
 
 Epithelial Cells
         Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
 
 Bone (Muscoskeletal System)
         HyStem+TGFbeta3+GDF5-induced E15 cells
 
 Cartilage (Muscoskeletal System)
         HyStem+TGFbeta3+GDF5-induced E15 cells
 
 Eye (Sensory Organs)
         Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
 
 Lung (Respiratory System)
MT1M Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

MT1M Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.647370
    Custom PCR Arrays for MT1M
Primer
Products:
OriGene qPCR primer pairs and template standards for MT1M
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat MT1M
QuantiTect SYBR Green Assays in human, mouse, rat MT1M
QuantiFast Probe-based Assays in human, mouse, rat MT1M
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MT1M

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus
  --

ENSEMBL Gene Tree for MT1M (if available)
TreeFam Gene Tree for MT1M (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section

TryGeneCards Plus
Paralogs for MT1M gene
MT1G2  MT1E2  MT1F2  MT1X2  MT1B2  MT2A2  MT1HL12  MT1H2  
MT1A2  
12 SIMAP similar genes for MT1M using alignment to 2 protein entries:     MT1M_HUMAN (see all proteins):
MT1A    MT1L    MT1G    MT1H    MT1B    MT1DP
MT1HL1    MT1X    MT1F    MTE    MT2A    MT1E

Find genes that share paralogs with MT1M           About GenesLikeMe


3 Pseudogenes.org Pseudogenes for MT1M
PGOHUM00000243912 PGOHUM00000243964 PGOHUM00000262507


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

Selected SNPs for MT1M (see all 121)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 16 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs559192751,2
C--56664582(+) TATTT-/ATT/
TTT
/TATT
GCACA
2 -- us2k1 cds11NA 2
rs1890045641,2
--57677432(+) TATTTA/GCACAT 1 -- us2k10--------
rs1815116121,2
--57677484(+) CTACCA/GCATGA 1 -- us2k10--------
rs71918001,2
C,F,A,H--57677527(+) AGTGTT/CCCCAC 1 -- us2k123Minor allele frequency- C:0.18NS EA NA WA CSA 2348
rs1462492171,2
--57677551(+) ACACTA/GGGGTT 1 -- us2k10--------
rs1857638611,2
--57677671(+) AATACG/TTCTTA 1 -- us2k10--------
rs1400640641,2
--57677734(+) ATCTTA/GTCTTA 1 -- us2k10--------
rs606682831,2
C--57677786(+) TGTGT-/GTGTGT
/GTGTGTGT
ATTAC
2 -- us2k1 cds11NA 2
rs1420729101,2
--57677802(+) TGGATC/TACTTT 1 -- us2k10--------
rs71929131,2
C,F,H--57677803(+) GGATTG/ACTTTT 1 -- us2k121Minor allele frequency- A:0.07NS EA NA WA CSA 1634

HapMap Linkage Disequilibrium report for MT1M (56666145 - 56667898 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for MT1M:    About this table    
Variant IDTypeSubtypePubMed ID
nsv906720CNV Loss21882294

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing MT1M
DNA2.0 Custom Variant and Variant Library Synthesis for MT1M

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus
OMIM gene information: 156357    OMIM disorders: --


Find genes that share disorders with MT1M           About GenesLikeMe


Export disorders for MT1M gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

TryGeneCards Plus

PubMed articles for MT1M gene, integrated from 10 sources (see all 18):
(articles sorted by number of sources associating them with MT1M)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Characterisation of six additional human metallothionein genes. (PubMed id 8049263)1, 3, 9 Stennard F.A.... West A.K. (Biochim. Biophys. Acta 1994)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  3. Human metallothionein genes: structure of the functional locus at 16q13. (PubMed id 2286373)1, 3 West A.K....Richards R.I. (Genomics 1990)
  4. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. (PubMed id 23398456)1 Bett J.S....Hay R.T. (Biochem. J. 2013)
  5. Metallothionein MT1M is a tumor suppressor of human hepatocellular carcinomas. (PubMed id 22971577)1 Mao J....Yu L. (Carcinogenesis 2012)
  6. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
  7. Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis. (PubMed id 17244347)1 Lederer C.W....Cavallaro S. (BMC Genomics 2007)
  8. HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages. (PubMed id 12539042)1 Izmailova E....Aldovini A. (Nat. Med. 2003)
  9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  10. Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes. (PubMed id 10774930)1 Vandeghinste N....De Ley M. (Cell. Mol. Biol. (Noisy-le-grand) 2000)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

TryGeneCards Plus
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

TryGeneCards Plus
Entrez Gene: 4499 HGNC: 14296 AceView: MT1BandMT1K Ensembl:ENSG00000205364 euGenes: HUgn4499
ECgene: MT1M Kegg: 4499 H-InvDB: MT1M

(According to HUGE)
About This Section

TryGeneCards Plus
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

TryGeneCards Plus
NameDescription
PharmGKB entry for MT1M Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section

TryGeneCards Plus
Patent Information for MT1M gene:
Search GeneIP for patents involving MT1M

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

TryGeneCards Plus

 
 EMD Millipore genomic analysis products

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
 Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for MT1M  
 OriGene qPCR primer pairs and template standards for MT1M   OriGene Protein Over-expression Lysate for MT1M  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for MT1M  
 Browse OriGene qSTAR qPCR primer pairs   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for MT1M   OriGene Custom Protein Services for MT1M  

 
 
 Block miRNA regulation of human, mouse, rat MT1M using miScript Target Protectors SeqTarget long-range PCR primers for resequencing MT1M
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MT1M Predesigned siRNA for gene silencing in human, mouse, rat MT1M
 QuantiFast Probe-based Assays in human, mouse, rat MT1M QuantiTect SYBR Green Assays in human, mouse, rat MT1M
 Custom PCR Arrays for MT1M Search Chromatin IP Primers for MT1M
 Pre-validated RT2 qPCR Primer Assay in human, mouse / rat MT1M  Search GeneGlobe Interaction Network for MT1M
 Regulatory tfbs in MT1M promoter
 GenScript Custom Purified and Recombinant Proteins Services for MT1M GenScript cDNA clones with any tag delivered in your preferred vector for MT1M
 GenScript Custom Assay Services for MT1M GenScript Custom overexpressing Cell Line Services for MT1M
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
 Search for Antibodies & Assays

 Search Tocris compounds for MT1M
 Browse Sino Biological Proteins
 Browse Sino Biological Cell Lysates
 Browse Sino Biological cDNA Clones
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 MT1M proteins
 MT1M lysates
 Search for Antibodies for MT1M at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for MT1M
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for MT1M
 Antibodies for MT1M
 ELISAs for MT1M
 CLIAs for MT1M



 Browse ESI BIO Cell Lines and PureStem Progenitors for MT1M
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MT1M
 SwitchGear 3'UTR luciferase reporter plasmids for MT1M
 Browse SwitchGear Promoter luciferase reporter plasmids for MT1M
 Search ThermoFisher Antibodies for MT1M
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MT1M
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MT1M
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MT1M
 Search LSBio for Antibodies for MT1M
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
 Search Addgene for plasmids for MT1M
  Search eBioscience for proteins for MT1M
  Search eBioscience for elisas for MT1M
  eBioscience FlowRNA Probe Sets
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

View Random Gene

Category
(GIFtS: )
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes       gene at Home site.
Version: 3.12.202 14 Sep 2014
hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4