Aliases for MOGAT2 Gene
External Ids for MOGAT2 Gene
Previous GeneCards Identifiers for MOGAT2 Gene
Dietary fat absorption from the small intestine is facilitated by acyl-CoA:monoacylglycerol transferase (MOGAT; EC 188.8.131.52) and acyl-CoA:diacylglycerol acyltransferase (DGAT; see MIM 604900) activities. MOGAT catalyzes the joining of monoacylglycerol and fatty acyl-CoAs to form diacylglycerol (Yen and Farese, 2003 [PubMed 12621063]).[supplied by OMIM, Mar 2008]
GeneCards Summary for MOGAT2 Gene
MOGAT2 (Monoacylglycerol O-Acyltransferase 2) is a Protein Coding gene. Among its related pathways are Transport to the Golgi and subsequent modification and Metabolism. GO annotations related to this gene include transferase activity, transferring acyl groups other than amino-acyl groups and 2-acylglycerol O-acyltransferase activity. An important paralog of this gene is MOGAT1.
UniProtKB/Swiss-Prot for MOGAT2 Gene
Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity.