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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MOGAT2 Gene

protein-coding   GIFtS: 54
GCID: GC11P075428

monoacylglycerol O-acyltransferase 2
 Explore 2 diseases affiliated with
MOGAT2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for MOGAT2    

Aliases
for MOGAT2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Monoacylglycerol O-Acyltransferase 21 2 3     HMGAT21
DGAT2L51 2 3     FLJ226441
MGAT21 2 3     2-Acylglycerol O-Acyltransferase 22
Acyl-CoA:Monoacylglycerol Acyltransferase 22 3     Acyl CoA:Monoacylglycerol Acyltransferase 22
Diacylglycerol Acyltransferase 2-Like Protein 52 3     DC53
Diacylglycerol O-Acyltransferase Candidate 52 3     EC 2.3.1.223
HDC51     EC 2.3.18

External Ids:    HGNC: 232481   Entrez Gene: 801682   Ensembl: ENSG000001663917   OMIM: 6102705   UniProtKB: Q3SYC23   

Export aliases for MOGAT2 gene to outside databases

Previous GC identifers: GC11P075156 GC11P075106 GC11P071726


Summaries
for MOGAT2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for MOGAT2:
Dietary fat absorption from the small intestine is facilitated by acyl-CoA:monoacylglycerol transferase (MOGAT; EC
2.3.1.22) and acyl-CoA:diacylglycerol acyltransferase (DGAT; see MIM 604900) activities. MOGAT catalyzes the joining
of monoacylglycerol and fatty acyl-CoAs to form diacylglycerol (Yen and Farese, 2003 (PubMed 12621063)).(supplied by
OMIM, Mar 2008)

UniProtKB/Swiss-Prot: MOGT2_HUMAN, Q3SYC2
Function: Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Has a preference toward
monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central
role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in
enterocytes. May play a role in diet-induced obesity

Gene Wiki entry for MOGAT2


Genomic Views
for MOGAT2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_167190.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MOGAT2 gene promoter:
         NF-1/L   NF-1   AML1a   ATF-2   Nkx5-1   PPAR-gamma1   GATA-6   PPAR-gamma2   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MOGAT2 promoter sequence
   Search SABiosciences Chromatin IP Primers for MOGAT2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MOGAT2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.5   Ensembl cytogenetic band:  11q13.5   HGNC cytogenetic band: 11q13.5

MOGAT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MOGAT2 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P075428:  view genomic region     (about GC identifiers)

Start:
 75,428,864 bp from pter      End:
 75,444,003 bp from pter
Size:
 15,140 bases      Orientation:
 plus strand

Proteins
for MOGAT2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: MOGT2_HUMAN, Q3SYC2 (See protein sequence)
Recommended Name: 2-acylglycerol O-acyltransferase 2  
Size: 334 amino acids; 38196 Da
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
Secondary accessions: A8K7I3 Q3SYC1 Q6ZQZ2 Q86UH6 Q9H630
Alternative splicing: 3 isoforms:  Q3SYC2-1   Q3SYC2-2   Q3SYC2-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MOGAT2: NX_Q3SYC2

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q3SYC2

    • 2 DME Specific Peptides for MOGAT2 (Q3SYC2)
     PITTVVG  PLFHGRGVF 

    MOGAT2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_079374.2  
    ENSEMBL proteins: 
     ENSP00000198801   ENSP00000436537   ENSP00000436283  

    Human Recombinant Protein Products: 
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    Novus Biologicals MOGAT2 Proteins
    Novus Biologicals MOGAT2 Lysates
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    Uscn Proteins for MOGAT2

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum IDA14966132
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0016021integral to membrane IEA--


    MOGAT2 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for MOGAT2

    Protein Domains /
    Families
    for MOGAT2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    MOGAT2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR007130 DAGAT

    Graphical View of Domain Structure for InterPro Entry Q3SYC2

    ProtoNet protein and cluster: Q3SYC2

    UniProtKB/Swiss-Prot: MOGT2_HUMAN, Q3SYC2
    Similarity: Belongs to the diacylglycerol acyltransferase family


    Function
    for MOGAT2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: MOGT2_HUMAN, Q3SYC2
    Function: Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Has a preference toward
    monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central
    role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in
    enterocytes. May play a role in diet-induced obesity
    Catalytic activity: Acyl-CoA + 2-acylglycerol = CoA + diacylglycerol
    Enzyme regulation: Inhibited by oleic acid and sphingosine, while it is stimulated by phosphatidylcholine,
    phosphatidylserine and phosphatidic acid (By similarity)
    Biophysicochemical properties: Kinetic parameters: KM=45 uM for sn-1-monooleoylglycerol;

    Enzyme Numbers (IUBMB): EC 2.3.12 EC 2.3.1.221

    miRNA
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    OriGene shRNA RFP: MOGAT2
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for MOGAT2

    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:00038462-acylglycerol O-acyltransferase activity IEA--
    GO:0016407acetyltransferase activity IEA--


    MOGAT2 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-outs for MOGAT2: Mogat2tm1.1Ryyo Mogat2tm1Far
         5 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Mogat2):
     adipose tissue  digestive/alimentary  growth/size  homeostasis/metabolism  liver/biliary system 

    MOGAT2 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for MOGAT2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1alpha-Linolenic acid metabolism
    		Fat digestion and absorption0.32
    2CDP-diacylglycerol biosynthesis I
    		Triacylglyceride Synthesis0.17

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for MOGAT2 
        Triacylglyceride Synthesis


    1         Kegg Pathway  (Kegg details for MOGAT2):
        Fat digestion and absorption

    UniProtKB/Swiss-Prot: MOGT2_HUMAN, Q3SYC2
    Pathway: Glycerolipid metabolism; triacylglycerol biosynthesis


    MOGAT2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MOGAT2

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/19 Interacting proteins for MOGAT2 (Q3SYC23 ENSP000001988014) via UniProtKB, MINT, STRING, and/or I2D (see all 19)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    NAPBQ9H1153I2D: score=2 
    COG3Q96JB23I2D: score=1 
    DNAJA1P316893I2D: score=1 
    EFTUD1Q7Z2Z23I2D: score=1 
    HSP90AA1P079003I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006071glycerol metabolic process IEA--
    GO:0006629lipid metabolic process ----
    GO:0006651diacylglycerol biosynthetic process IEA--
    GO:0019432triglyceride biosynthetic process IEA--
    GO:0050892intestinal absorption IEA--


    MOGAT2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for MOGAT2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MOGAT2

    10/2438 HMDB Compounds for MOGAT2 (see all 2438)    About this table
    CompoundSynonyms CAS #PubMed Ids
    DG(16:0e/18:0/0:0)2-Octadecanoyl-1-hexadecyl-sn-glycerol (see all 2)--12486725
    (2E)-Decenoyl-CoA(E)-S-2-decenoate Coenzyme A (see all 15)10018-95-8--
    (2E)-Dodecenoyl-CoA2-trans-Dodecenoyl-Coenzyme A (see all 4)1066-12-2--
    (2E)-Hexadecenoyl-CoAtrans-2-Hexadecenoyl-CoA (see all 4)4460-95-1--
    (2E)-Octenoyl-CoA(E)-S-2-octenoate Coenzyme A (see all 16)10018-94-7--
    (2E)-Tetradecenoyl-CoA(2E)-Tetradecenoyl-Coenzyme A (see all 8)38795-33-4--
    2-Arachidonylglycerol2-Arachidonyl glycerol;(all-Z)-2-hydroxy-1-(hydroxymethyl)ethyl ester 5,8,11,14-Eicosatetraenoic acid (see all 21)53847-30-6--
    2-Methylbutyryl-CoA2-methylbutanoyl-CoA (see all 11)6712-02-3--
    2-Methylhexanoyl-CoA2-Methylhexanoyl-CoEnzyme A (see all 5)----
    3Z-dodecenoyl-CoAS-[2-[3-[[(2R)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (Z)-dodec-3-enethioate (see all 4)2152-91-2--
    Search CenterWatch for drugs/clinical trials and news about MOGAT2 / MOGT2 

    Transcripts
    for MOGAT2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for MOGAT2 gene: 
    NM_025098.2  

    Unigene Cluster for MOGAT2:

    Monoacylglycerol O-acyltransferase 2
    Hs.288568  [show with all ESTs]
    Unigene Representative Sequence: AK128620
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000198801(uc010rru.2) ENST00000525093(uc001oww.1) ENST00000526712(uc010rrv.2)
    ENST00000528955

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    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MOGAT2 (see all 7)
    OriGene shRNA RFP: MOGAT2
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    Clone
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    Additional cDNA sequence: 

    AK000245.1 AK026297.1 AK128620.1 AK291998.1 AY157608.1 BC103876.1 BC103877.1 BC103878.1 
    Z11852.1 

    5 DOTS entries:

    DT.101979655  DT.100741159  DT.91973467  DT.92068044  DT.102820712 

    24/27 AceView cDNA sequences (see all 27):

    AK000245 AK128620 AY157608 NM_025098 AA722886 AK026297 BX482703 BG674053 
    BM819465 AW852653 BF374729 BF374574 CD632454 AW810630 AW852902 AW841567 
    CD632453 BF374587 AW176389 BF374606 BG980610 BG980611 AW809961 AW809845 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for MOGAT2    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b
    SP1:              -                             -               
    SP2:              -                             -               
    SP3:                                            -               
    SP4:              -                                             


    ECgene alternative splicing isoforms for MOGAT2

    Expression
    for MOGAT2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MOGAT2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GAATGCCATA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    MOGAT2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    6 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    AdiposeVisceral White AdiposeVisceral White AdipocytesAdipose
    BrainBlood Brain BarrierEndothelial CellsBlood Brain Barrier, Endothelium
    BrainBlood Brain BarrierPostnatal Endothelial CellsBlood Brain Barrier, Endothelium
    KidneyProximal TubuleProximal Tubule CellsKidney
    KidneyEpithelial TubuleKidney
    KidneyProximal TubuleKidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See MOGAT2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MOGAT2

    SOURCE GeneReport for Unigene cluster: Hs.288568

    UniProtKB/Swiss-Prot: MOGT2_HUMAN, Q3SYC2
    Tissue specificity: Highly expressed in liver, small intestine, colon, stomach and kidney

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    In Situ
    Assay Products:     
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    Orthologs
    for MOGAT2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MOGAT2 gene from 7/25 species (see all 25)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves MOGAT21 monoacylglycerol O-acyltransferase 2 69.08(n)
    69.88(a)    		   426437  XM_424082.3  XP_424082.3 
    lizard
    (Anolis carolinensis)    		 Reptilia MOGAT26
    		 --
    		 61(a)
    		 1 ↔ 1
    		 GL343298.1(1211312-1246626)
    zebrafish
    (Danio rerio)    		 Actinopterygii mogat21 monoacylglycerol O-acyltransferase 2 63.75(n)
    65.74(a)    		   450063  NM_001006083.1  NP_001006083.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG19421 CG1942 48.86(n)
    41.61(a)    		   35719  NM_136474.2  NP_610318.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea Y53G8B.26
    F59A1.106
    (see all 4)    		 Protein F59A1.10
    (see all 4)    		 42(a)
    42(a)
    (see all 4)    		 possible ortholog
    possible ortholog
    (see all 4)    		 III(3101222-3103949)
    V(17660278-17661785)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT3G515206
    		 diacylglycerol O-acyltransferase 2
    		 26(a)
    		 possible ortholog
    		 3(19110596-19112760)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    		 diacylglycerol O-acyltransferase, putative, expres...
    diacylglycerol O-acyltransferase, putative, expres...
    		 24(a)
    24(a)
    		 possible ortholog
    possible ortholog
    		 6(12808567-12811496)
    2(29593105-29595977)


    ENSEMBL Gene Tree for MOGAT2 (if available)
    TreeFam Gene Tree for MOGAT2 (if available) 

    Paralogs
    for MOGAT2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MOGAT2 gene
    MOGAT32  DGAT2L7P2  MOGAT12  DGAT22  DGAT2L62  AWAT22  AWAT12  
    7 SIMAP similar genes for MOGAT2 using alignment to 1 protein entry:     MOGT2_HUMAN:
    MOGAT1    DGAT2    MOGAT3    AWAT1    AWAT2    DGAT2L6
    DGAT2L7P

    MOGAT2 for paralogs           About GeneDecksing



    Genomic Variants
    for MOGAT2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/346 NCBI SNPs in MOGAT2 are shown (see all 346)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 11 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs122949691,2
    		C,F,H,--75427074(+) AGTTGT/CTAGGA 1 -- us2k16Minor allele frequency- C:0.07NS EA WA 540
    rs1153523561,2
    		--75427250(+) GAAATG/ATGTAT 1 -- us2k11Minor allele frequency- A:0.01WA 118
    rs794813411,2
    		F,--75427261(+) AGATGT/AGTACT 1 -- us2k11Minor allele frequency- A:0.04WA 118
    rs1454063981,2
    		--75427279(+) ATGTAA/CAGGAA 1 -- us2k10--------
    rs1472732791,2
    		--75427313(+) ATAGCC/TAGAAA 1 -- us2k10--------
    rs6951551,2
    		C,F,A,H,--75427612(+) TGTCCA/GCTTAG 1 -- us2k133Minor allele frequency- G:0.19NS EA NA WA CSA 3026
    rs1862167261,2
    		--75427618(+) CTTAGG/TATTTG 1 -- us2k10--------
    rs1408901761,2
    		--75427621(+) AGGATC/TTGTGC 1 -- us2k10--------
    rs1891283721,2
    		--75427676(+) AAAAGA/GAGGGA 1 -- us2k10--------
    rs1498289341,2
    		--75427792(+) TTACCC/TTTTAC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for MOGAT2 (75428864 - 75444003 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for MOGAT2: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MOGAT2
    DNA2.0 Custom Variant and Variant Library Synthesis for MOGAT2

    Disorders / Diseases
    for MOGAT2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    MOGAT2 for disorders           About GeneDecksing

    OMIM gene information: 610270    OMIM disorders: --

    2 diseases for MOGAT2:    About MalaCards
    obesity    alcoholism


    Export disorders for MOGAT2 gene to outside databases

    Publications
    for MOGAT2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MOGAT2 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with MOGAT2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Human intestinal monoacylglycerol acyltransferase: differential features in tissue expression and activity. (PubMed id 12824082)1, 2 Lockwood J.F.... Shi Y. (2003)
    4. Genomic organization of the DGAT2/MOGAT gene family in cattle (Bos taurus) and other mammals. (PubMed id 14970677)1, 3 Winter A....Fries R. (2003)
    5. MGAT2, a monoacylglycerol acyltransferase expressed in the small intestine. (PubMed id 12621063)1, 2 Yen C.-L.E. and Farese R.V. Jr. (2003)
    6. A predominant role of acyl-CoA:monoacylglycerol acyltransferase-2 in dietary fat absorption implicated by tissue distribution, subcellular localization, and up-regulation by high fat diet. (PubMed id 14966132)1, 9 Cao J....Shi Y. (2004)
    7. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    8. Insights into the bile acid transportation system: the human ileal lipid-binding protein-cholyltaurine complex and its comparison with homologous structures. (PubMed id 12486725)6 Kurz M....Kramer W. (2003)
    9. Cloning and functional characterization of a mouse intestinal acyl-CoA:monoacylglycerol acyltransferase, MGAT2. (PubMed id 12576479)1 Cao J....Shi Y. (2003)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    External Searches for MOGAT2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing MOGAT2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80168 HGNC: 23248 AceView: MOGAT2 Ensembl:ENSG00000166391 euGenes: HUgn80168
    ECgene: MOGAT2 Kegg: 80168 H-InvDB: MOGAT2

    Other Databases showing MOGAT2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing MOGAT2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MOGAT2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for MOGAT2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for MOGAT2 gene:
    Search GeneIP for patents involving MOGAT2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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