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MGAM Gene

protein-coding GIFtS: 53

GC07P141342

maltase-glucoamylase (alpha-glucosidase)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
MG ^²
MGA ^¹, ², ³, ⁵
MGAML ^³
alpha-glucosidase ^²
maltase-glucoamylase ^²

Descriptions
brush border hydrolase ^²
maltase-glucoamylase (alpha-glucosidase) ^²

External Ids
HGNC: 7043¹
Entrez Gene: 8972²
UniProtKB: O43451³
Ensembl: ENSG00000179087⁷

Search outside databases for aliases for MGAM gene

Previous GC identifers: GC07P139967 GC07P140976 GC07P141102 GC07P141148

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for MGAM:

This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role

in the final steps of digestion of starch. The protein has two catalytic sites identical to those

of sucrase-isomaltase, but the proteins are only 59% homologous. Both are members of glycosyl

hydrolase family 31, which has a variety of substrate specificities. [provided by RefSeq]

UniProtKB/Swiss-Prot: MGA_HUMAN, O43451

Function: May serve as an alternate pathway for starch digestion when luminal alpha-amylase

activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion

of malted dietary oligosaccharides used in food manufacturing

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the MGAM gene

Entrez Gene cytogenetic band: 7q34 Ensembl cytogenetic band: 7q34 HGNC cytogenetic band: 7q34

MGAM Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07P141342: (about GC identifiers)

Start:	141,342,148 bp from pter
End:	141,453,016 bp from pter
Size:	110,869 bases
Orientation:	plus strand

1 alternative location:

Chr7+,CRA_TCAG 141,033,874-141,144,746

RefSeq DNA sequence:

NC_000007.12 NT_007914.14 NT_079596.2

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: MGA_HUMAN, O43451 (See protein sequence)

Recommended Name: Maltase-glucoamylase, intestinal

Size: 1857 amino acids; 209852 Da

Subunit: Monomer

Subcellular location: Apical cell membrane; Single-pass type II membrane protein. Note=Brush border

PDB structures from and Proteopedia :

2QLY (3D)

2QMJ (3D)

3CTT (3D)

Secondary accessions: Q0VAX6 Q75ME7 Q86UM5

Post-translational modifications:

N- and O-glycosylated¹

Does not undergo intracellular or extracellular proteolytic cleavage¹

Sulfated (By similarity)¹

REFSEQ proteins: NP_004659.2

ENSEMBL proteins:

ENSP00000316431 ENSP00000373973

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
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	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0016021	integral to membrane	IEA	--
GO:0016324	apical plasma membrane	IEA	--

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Antibodies for MGAM:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for MGAM
	Browse R&D Systems for Antibodies
	Search for antibodies at Abcam and the World's Antibody Gateway (free search engine of over 150 antibody companies)
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for MGAM

Assays for MGAM:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry O43451

ProtoNet protein and cluster: O43451

1 Blocks protein family: IPB000519 P-type trefoil domain

UniProtKB/Swiss-Prot: MGA_HUMAN, O43451

Similarity: Belongs to the glycosyl hydrolase 31 family

Similarity: Contains 2 P-type (trefoil) domains

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MGAM)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004668

Applied Biosystems Silencer® siRNAs for MGAM

Sigma-Aldrich siRNA and siRNA Panels for MGAM

Sigma-Aldrich shRNA for MGAM

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_004668
Myc/DDK tagged cDNA clone in CMV expression vector: NM_004668
untagged cDNA clone in CMV expression vector: NM_004668

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_004668

UniProtKB/Swiss-Prot: MGA_HUMAN, O43451

Function: May serve as an alternate pathway for starch digestion when luminal alpha-amylase

activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion

of malted dietary oligosaccharides used in food manufacturing

Catalytic activity: Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues

with release of alpha-D-glucose

Catalytic activity: Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from

non-reducing ends of the chains with release of beta-D-glucose

Genatlas biochemistry entry for MGAM:

maltase-glucoamylase,alpha-glucosidase,expressed in the small intestine,member of the glucosyl

hydrolase family 31,playing a unique role in the digestion of malted dietary oligosaccharides

1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Mgam):

homeostasis/metabolism

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004339	glucan 1,4-alpha-glucosidase activity	IEA	--
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	IEA	--
GO:0004558	alpha-glucosidase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

2 Sigma-Aldrich "Your Favorite Gene" Pathways for MGAM (Your Favorite Gene powered by Ingenuity)

Galactose Metabolism
Starch and Sucrose Metabolism

GeneDecks MGAM for the pathways selected above

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Gene Network Central^TM Interacting Genes and Proteins Network for MGAM

5/55 Interacting proteins for MGAM (ENSP00000316431³) via UniProtKB, MINT, and/or STRING (see all 55 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
AMY2A	ENSP00000306915³	STRING (score=.972)
AGL	ENSP00000309020³	STRING (score=.962)
GBA	ENSP00000357357³	STRING (score=.946)
GBA3	ENSP00000314501³	STRING (score=.924)
ACSL1	ENSP00000281455³	STRING (score=.909)

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005975	carbohydrate metabolic process	IEA	--
GO:0005983	starch catabolic process	TAS	9446624
GO:0008152	metabolic process	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for MGAM
10/42 Novoseek chemical compound relationships for MGAM gene (see all 42 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
salacinol	94.54	14	18295754 (3), 16438529 (1), 17194097 (1), 16817895 (1) (see all 10)
maltose	80.75	31	16702880 (3), 9336980 (2), 9680991 (1), 1525871 (1) (see all 24)
isomaltose	75.15	8	9605546 (3), 9605547 (2), 1970434 (1), 7716159 (1)
cyclomaltodextrin	60.46	1	15178396 (1)
glucose	58.52	94	15269621 (5), 9605546 (3), 18356321 (3), 1369368 (2) (see all 41)
alpha-1,4-glucan	58.30	2	15063197 (1), 1952934 (1)
maltoheptaose	56.72	1	1970434 (1)
maltohexaose	55.58	2	11890888 (1), 9099629 (1)
adipic acid dihydrazide	55.31	3	1369368 (1), 1416949 (1)
cysteine sulfinic acid	55.21	6	9521693 (3), 9521694 (2), 10491591 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MGAM)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004668

Sigma-Aldrich siRNA and siRNA Panels for MGAM

Sigma-Aldrich shRNA for MGAM

Explore Sigma-Aldrich super-pooled esiRNAs

REFSEQ mRNAs for MGAM gene:

NM_004668.2

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_004668
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_004668
                                 untagged cDNA clone in CMV expression vector: NM_004668

Additional cDNA sequence:

AF016833.2 AK127838.1 BC120872.1

3 DOTS entries:

DT.105116 DT.101976434 DT.307101

24/36 AceView cDNA sequences (see all 36 ):

AI249749 AF016833 BE501913 BE501751 BE501528 BX099576 AW468532 AI474873

AI733054 AA411968 BU684758 AA894763 AA412675 CK301106 NM_004668 AK127838

BP383005 BX645594 AI566134 AA846103 AA412737 AI791544 AI796060 BG721366

highest scoring ESTs for MGAM:

AF016833 AA846103 AA894763 AI249749 AI283735 AI479207 AI566134 AI701651 AI733054 AI791544

Unigene Cluster for MGAM:

Maltase-glucoamylase (alpha-glucosidase)

Hs.122785 [show with all ESTs]

Unigene Representative Sequence: NM_004668

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for MGAM (see all 6 )

ExUns:	1a	·	1b	^	2	^	3	^	4a	·	4b	^	5a	·	5b	·	5c	^	6a	·	6b	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16	^	17
SP1:					-
SP2:
SP3:
SP4:					-						-		-
SP5:

About this scheme

ECgene alternative splicing isoforms for MGAM

2 Ensembl transcripts including schematic representations:

ENST00000312952 ENST00000389322

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

MGAM expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for MGAM

¹ / ² / ³

3 probe-sets matching MGAM gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
34509_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	AF016833	1.00	1.00	1.00	1
206522_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_004668	0.60	1.00	0.82	1
206522_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks MGAM for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GGGAGGAAAA

SOURCE GeneReport for Unigene cluster: Hs.122785
Expression variation in blood from EXPOLDB for MGAM
UniProtKB/Swiss-Prot: MGA_HUMAN, O43451
Tissue specificity: Expressed in small intestine, granulocyte, and kidney but not in salivary gland
or pancreas

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for MGAM gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	MGAM¹	--	maltase-glucoamylase (alpha-glucosidase)	86.95(n) 86.32(a)	475523 XM_532746.2 XP_532746.2
mouse (Mus musculus)	Mgam^{1, 5}	6⁵	maltase-glucoamylase^{1, 5}	80.32(n)¹ 78.47(a)¹	232714¹ XM_001481277.1¹ XP_001481327.1¹ AI641851⁵ AK031332⁵ (see all 10)
zebrafish (Danio rerio)	LOC100148922¹	--	similar to maltase-glucoamylase	60.66(n) 57.32(a)	100148922 XM_001919100.1 XP_001919135.1
worm (Caenorhabditis elegans)	D2096.3³	IV(8363651-8375533)	--	39(a) (best of 3)	--
thale cress (Arabidopsis thaliana)	AT5G11720¹	--	alpha-glucosidase 1 (AGLU1)	48.57(n) 40.86(a)	831044 NM_121210.2 NP_196733.1

About this table Species with no ortholog for MGAM

ENSEMBL Gene Tree for MGAM

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for MGAM gene

ENSG00000204987² SI² LOC93432²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/836 NCBI SNPs in MGAM are shown (see all 836 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 165)

AB	SNP ID	Valid	Chr 7 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs1554778^1,2	A,C,F,H	141341030(+)	`ttgcaA/Gagcag`	1	--	ng5¹		7		EU EA WA NA	546
	rs2272330^1,2	A,C,F,H	141373995(+)	`GCACAG/TCTCCC`	1	Q/H	mis¹ ese³		14		EA NA EU WA	1894
--	rs1985729^1,2	A,C,F	141341274(+)	`TGGTTG/ATGTGA`	1	--	ng5¹		8		NA EA MN	772
	rs10266732^1,2	C,F,H	141379134(+)	`GGTCTC/TAGGAT`	1	S/L	mis¹ ese³		4		EU EA WA	404
	rs13437780^1,2	C,F,H	141340691(+)	`ttgatT/Aggcag`	1	--	ng5¹ tfbs³		8		EU EA WA	840
--	rs9655651^1,2	C,F,H	141441975(+)	`CTCTGC/ATCCAT`	1	I/L	mis¹		8		EU EA WA	840
	rs2960746^1,2	C,F,H	141394127(+)	`GGGATG/AATGGG`	1	N/D	mis¹ ese³		8		EU EA WA	836
	rs12534052^1,2	C,F	141453114(+)	`CTCTTC/TGGCAT`	1	--	ng3¹		4		NA EA	362
--	rs1609100^1,2	A,C	141340737(+)	`gtgcaA/Gctgag`	1	--	ng5¹ tfbs³		0	--	--	--	--
	rs10229158^1,2	H	141340823(+)	`tatctA/Caaaga`	1	--	ng5¹		4		EU EA WA	416

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HapMap Linkage Disequilibrium images for MGAM (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 154360

10/17 Novoseek disease relationships for MGAM gene (see all 17 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
disaccharidase deficiencies	75.59	1	8151467 (1)
lactase deficiency	62.48	1	12394387 (1)
pompe disease	59.87	4	16702880 (2), 16763908 (1)
enzyme deficiency	46.83	1	12394387 (1)
diarrhea chronic	37.75	4	12519224 (2), 12394383 (1), 8151467 (1)
atrophy	26.45	4	11346204 (2), 10817278 (1)
colon adenocarcinoma	21.86	1	9438518 (1)
malnutrition	18.51	5	7896332 (2), 8125391 (1), 9446624 (1)
bowel disease	5.84	1	17671629 (1)
cancer	0.65	3	1281900 (1), 1515557 (1)

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Genatlas disease: MGAM

diarrhea in children associated with starch malabsorption and small intestinal glucoamylase

deficiency

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/261 PubMed articles for MGAM gene (see all 261 ):

Human small intestinal maltase-glucoamylase cDNA cloning. Homology to sucrase-isomaltase. (PubMed id 9446624)^{1, 2, 3, 4} Nichols B.L....Sterchi E.E. (1998)
Human intestinal maltase-glucoamylase: crystal structure of the N-terminal catalytic subunit and basis of inhibition and substrate specificity. (PubMed id 18036614)^{1, 3, 4} Sim L....Rose D.R. (2008)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{3, 4} Hillier L.W.... Wilson R.K. (2003)
Structure, biosynthesis, and glycosylation of human small intestinal maltase-glucoamylase. (PubMed id 3143729)^{3, 4} Naim H.Y.... Lentze M.J. (1988)
Tyrosine sulfation, a post-translational modification of microvillar enzymes in the small intestinal enterocyte. (PubMed id 3121301)^{3, 4} Danielsen E.M. (1987)
The maltase-glucoamylase gene: common ancestry to sucrase-isomaltase with complementary starch digestion activities. (PubMed id 12547908)^{1, 3} Nichols B.L.... Sterchi E. (2003)
Clinical, endocrine, and metabolic effects of acarbose, a alpha-glucosidase inhibitor, in overweight and nonoverweight patients with polycystic ovarian syndrome. (PubMed id 18377903)³ Tugrul S....Oral O. (2008)
Evidence of native starch degradation with human small intestinal maltase-glucoamylase (recombinant). (PubMed id 17485087)³ Ao Z....Hamaker B.R. (2007)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)⁴ Gerhard D.S....Malek J. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 8972	HGNC: 7043	AceView: MGAM	Ensembl:ENSG00000179087	euGenes: HUgn8972
ECgene: MGAM	H-InvDB: MGAM

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Licensable Technologies for MGAM
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for MGAM:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for MGAM-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for MGAM		Antibodies for MGAM
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for MGAM		Browse small molecules at Sigma-Aldrich
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MGAM Gene

protein-coding GIFtS: 53

Aliases &
Descriptions
for MGAM

Summaries
for MGAM

Genomic Location
for MGAM

Proteins
for MGAM

Protein Domains/
Families
for MGAM

Gene Function
for MGAM

Pathways & Interactions
for MGAM

Drugs & Compounds
for MGAM

Transcripts
for MGAM

Expression
for MGAM

Orthologs
for MGAM

Paralogs
for MGAM

SNPs/Variants
for MGAM

Disorders & Mutations
for MGAM

Medical News
for MGAM

Publications
for MGAM

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Genome Databases showing MGAM

Other Databases showing MGAM

Specialized Databases showing MGAM

Licensable Technologies
for MGAM

Services
for MGAM

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

MGAM Gene

protein-coding GIFtS: 53

Aliases & Descriptionsfor MGAM

Summariesfor MGAM

Genomic Locationfor MGAM

Proteinsfor MGAM

Protein Domains/Familiesfor MGAM

Gene Functionfor MGAM

Pathways & Interactionsfor MGAM

Drugs & Compoundsfor MGAM

Transcriptsfor MGAM

Expression for MGAM

Orthologsfor MGAM

Paralogsfor MGAM

SNPs/Variantsfor MGAM

Disorders & Mutationsfor MGAM

Medical Newsfor MGAM

Publicationsfor MGAM

Search for MGAM

Genome Databases showing MGAM

Other Databases showing MGAM

Specialized Databases showing MGAM

Licensable Technologiesfor MGAM

Servicesfor MGAM

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for MGAM

Summaries
for MGAM

Genomic Location
for MGAM

Proteins
for MGAM

Protein Domains/
Families
for MGAM

Gene Function
for MGAM

Pathways & Interactions
for MGAM

Drugs & Compounds
for MGAM

Transcripts
for MGAM

Expression
for MGAM

Orthologs
for MGAM

Paralogs
for MGAM

SNPs/Variants
for MGAM

Disorders & Mutations
for MGAM

Medical News
for MGAM

Publications
for MGAM

Licensable Technologies
for MGAM

Services
for MGAM