Aliases for LIPC Gene
External Ids for LIPC Gene
Previous GeneCards Identifiers for LIPC Gene
LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. [provided by RefSeq, Jul 2008]
GeneCards Summary for LIPC Gene
LIPC (Lipase C, Hepatic Type) is a Protein Coding gene. Diseases associated with LIPC include Hepatic Lipase Deficiency and High Density Lipoprotein Cholesterol Level Quantitative Trait Locus 12. Among its related pathways are the visual cycle I (vertebrates) and triacylglycerol degradation. Gene Ontology (GO) annotations related to this gene include heparin binding and phospholipase activity. An important paralog of this gene is LPL.
UniProtKB/Swiss-Prot for LIPC Gene
Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin.