IMPA2 Gene
protein-coding GIFtS: 66
GCID: GC18P011971
|
|
inositol(myo)-1(or 4)-monophosphatase 2
| |
Aliases
for IMPA2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Inositol(Myo)-1(Or 4)-Monophosphatase 21 2 | | Inositol Monophosphatase 22 | | Myo-Inositol Monophosphatase A22 3 | | Inositol Monophosphatase 2 Variant 12 | | IMP 22 3 | | Inositol Monophosphatase 2 Variant 22 | | IMPase 22 3 | | IMP.18P3 | | EC 3.1.3.253 8 | | Inositol-1(Or 4)-Monophosphatase 23 | | Inosine Monophosphatase 22 | | |
Export aliases for IMPA2 gene to outside databasesPrevious GC identifers: GC18P012247 GC18P012038 |
Summaries
for IMPA2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for IMPA2:
This locus encodes an inositol monophosphatase. The encoded protein catalyzes the dephosphoylration of inositolmonophosphate and plays an important role in phosphatidylinositol signaling. This locus may be associated withsusceptibility to bipolar disorder. (provided by RefSeq, Jan 2011)
UniProtKB/Swiss-Prot: IMPA2_HUMAN, O14732Function: Can use myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate,beta-glycerophosphate, and 2'-AMP as substrates. Has been implicated as the pharmacological target for lithium Li(+)action in brain
Gene Wiki entry for IMPA2
|
Genomic Views
for IMPA2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000018.9 NC_018929.1 NT_010859.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the IMPA2 gene promoter:
TBP HOXA3 C/EBPalpha Arnt N-Myc Zic1 ZIC2/Zic2 LyF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for IMPA2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IMPA2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 18p11.2 Ensembl cytogenetic band: 18p11.21 HGNC cytogenetic band: 18p11.2IMPA2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 18 GeneLoc Exon Structure GeneLoc location for GC18P011971: view genomic region
(about GC identifiers)
Start:
|
11,981,024 bp from pter |
End:
|
12,030,876 bp from pter |
Size:
|
49,853 bases |
Orientation:
|
plus strand |
|
Proteins
for IMPA2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: IMPA2_HUMAN, O14732 (See
protein sequence)Recommended Name: Inositol monophosphatase 2 Size: 288 amino acids; 31321 Da
Cofactor: Magnesium
Subunit: Homodimer
5 PDB 3D structures from  and Proteopedia  for IMPA2:2CZH (3D)
2CZI (3D)
2CZK (3D)
2DDK (3D)
2FVZ (3D)
Secondary accessions: B0YJ29 Q9UJT3Alternative splicing: 2 isoforms: O14732-1 O14732-2 Explore the universe of human proteins at neXtProt for IMPA2: NX_O14732
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O14732
4 DME Specific Peptides for IMPA2 (O14732)
IMPA2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055029.1
ENSEMBL proteins: ENSP00000465416 ENSP00000269159 ENSP00000466059 ENSP00000372867 ENSP00000465938 ENSP00000464767 ENSP00000464754 Reactome Protein details: O14732
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table
IMPA2 for ontologies About GeneDecksing
IMPA2 Antibody Products:
Assay Products for IMPA2: |
Protein
Domains /
Families
for IMPA2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
IMPA2 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O14732ProtoNet protein and cluster: O14732 UniProtKB/Swiss-Prot: IMPA2_HUMAN, O14732Similarity: Belongs to the inositol monophosphatase family |
Function
for IMPA2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: IMPA2_HUMAN, O14732Function: Can use myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate,beta-glycerophosphate, and 2'-AMP as substrates. Has been implicated as the pharmacological target for lithium Li(+)action in brainCatalytic activity: Myo-inositol phosphate + H(2)O = myo-inositol + phosphateEnzyme regulation: Inhibited by high Li(+) and restricted Mg(2+) concentrationsBiophysicochemical properties: Kinetic parameters: KM=5 mM for myo-inositol 1-monophosphate; pH dependence: Optimum pHis 7.5-8.0;Induction: Repressed by Li(+) Genatlas biochemistry entry for IMPA2:inositol(myo)-1(or 4)-monophosphatase 2,widely expressed in adult and fetal tissues but minimally in brain
Enzyme Number (IUBMB): EC 3.1.3.251 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IMPA2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IMPA2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: IMPA2 (NM_014214) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IMPA2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IMPA2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IMPA2 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
IMPA2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for IMPA2:
Animal Models:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Impa2):
IMPA2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for IMPA2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | D-myo-inositol (1,3,4)-trisphosphate biosynthesis | | | 2 | Inositol phosphate metabolism | | | 3 | Metabolism | | | 4 | myo-inositol biosynthesis | | | 5 | Synthesis of IP3 and IP4 in the cytosol | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3  BioSystems Pathways for IMPA2
3 
Reactome Pathways for IMPA2
3 
Kegg Pathways (Kegg details for IMPA2):
UniProtKB/Swiss-Prot: IMPA2_HUMAN, O14732Pathway: Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 2/2
IMPA2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IMPA2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 22)
5/24 Interacting proteins for IMPA2 (O147322, 3 ENSP000002691594) via UniProtKB, MINT, STRING, and/or I2D (see all 24)
About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
IMPA2 for ontologies About GeneDecksing
|
Drugs & Compounds
for IMPA2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
IMPA2 for compounds About GeneDecksing
 Browse Tocris compounds for IMPA2
9 HMDB Compounds for IMPA2 About this table
1 DrugBank Compound for IMPA2 About this table
4 Novoseek chemical compound relationships for IMPA2 gene About this table
Search CenterWatch for drugs/clinical trials and news about IMPA2
|
Transcripts
for IMPA2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for IMPA2 gene: NM_014214.2 Unigene Cluster for IMPA2: Inositol(myo)-1(or 4)-monophosphatase 2 Hs.743311 [show with all ESTs]Unigene Representative Sequence: BM92485511 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000588752 ENST00000589238 ENST00000269159(uc002kqp.2 uc021uhq.1)
ENST00000590107 ENST00000383376(uc010dlb.2) ENST00000590138 ENST00000588927
ENST00000588863 ENST00000588167 ENST00000586230 ENST00000589374
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IMPA2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IMPA2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: IMPA2 (NM_014214) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IMPA2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IMPA2 |
Additional cDNA sequence: AF014398.2 AF200432.1 BC017176.1 BC031560.1 BT007061.1 13 DOTS entries: DT.451139 DT.100811697 DT.100811700 DT.215570 DT.101968557 DT.92436650 DT.100811702 DT.121104557 DT.92034497 DT.100028425 DT.100805305 DT.102824911 DT.91743402 24/269 AceView cDNA sequences (see all 269): BG740213 BX284019 BI060040 BG164583 AI765896 BI759488 BQ933557 CB243545 BE222765 BG742941 BF819453 BM927957 BI092728 CR594604 BE222751 BX350328 BM854579 BE547974 CR622241 BG698388 BE783021 BM694687 NM_014214 BF819359
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for IMPA2 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 |
|---|
|
| SP1: | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | - | | - | | - | | | | - | | | | | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | | | - | | | | | | | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | | | - | | | | - | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for IMPA2
|
Expression
for IMPA2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| IMPA2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCAGTGGCTC
About this image
See IMPA2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IMPA2
SOURCE GeneReport for Unigene cluster: Hs.743311
SABiosciences Custom PCR Arrays for IMPA2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IMPA2
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IMPA2 |
Orthologs
for IMPA2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for IMPA2 gene from 8/27 species (see all 27) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
IMPA21 |
inositol(myo)-1(or 4)-monophosphatase 2 |
77.24(n)
84.32(a) |
|
421032 XM_419118.3 XP_419118.1 |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.150172 |
Transcribed sequence with moderate similarity to protein more |
76.17(n) |
|
AL872125.2 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc:1102011 |
zgc:110201 |
65.93(n)
69.74(a) |
|
553595 NM_001020572.1 NP_001018408.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG93913
CG93891 |
dephosphorylation myo-inositol-1(or
4)-monophosphatase3
CG93891 |
46(a)
(best of 5)3
49.64(n)1
43.43(a)1 |
|
78C33
403471 NM_141038.31 NP_649295.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
F13G3.53 |
myo-inositol-1-monophosphatase |
43(a) |
|
I(7309454-7311033) -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
VTC46 |
inositol-phosphate phosphatase |
44(a) |
1 → many |
3(627512-629845) |
rice
(Oryza sativa) |
Liliopsida |
-- |
inositol-1-monophosphatase, putative, expressed |
44(a) |
1 → many |
3(21680459-21683561) |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
suhB6 |
inositol monophosphatase |
32(a) |
1 → many |
Chromosome(2661464-2662267) |
ENSEMBL Gene Tree for IMPA2 (if available)
TreeFam Gene Tree for IMPA2 (if available) |
Paralogs
for IMPA2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for IMPA2 gene
- IMPA12
1 SIMAP similar gene for IMPA2 using alignment to 13 protein entries: IMPA2_HUMAN (see all proteins):IMPA1
IMPA2 for paralogs About GeneDecksing
|
Genomic Variants
for IMPA2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 18 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for IMPA2 (11981024 - 12030876 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for IMPA2
1 CNV: 4051
1 Indel: 60256
Human Gene Mutation Database (HGMD): IMPA2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IMPA2 |
|
Disorders
/ Diseases
for IMPA2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
IMPA2 for disorders About GeneDecksing
OMIM gene information: 605922
OMIM disorders: --
10  diseases for IMPA2: About MalaCardsbipolar disorder bipolar affective disorder febrile seizures seizures
schizophrenia pneumonia tuberculosis leukemia
neuronitis mycobacterium tuberculosis
1 disease from the University of Copenhagen DISEASES database for IMPA2:Schizophrenia 4 Novoseek disease relationships for IMPA2 gene About this table
Genetic Association Database (GAD): IMPA2
Human Genome Epidemiology (HuGE) Navigator: IMPA2 (8 documents)
Export disorders for IMPA2 gene to outside databases
|
Publications
for IMPA2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for IMPA2 gene, integrated from 9 sources (see all 33):
(articles sorted by number of sources associating them with IMPA2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1. (PubMed id 17068342)1, 2, 7, 9 Ohnishi T....Yoshikawa T. (2007)
- A novel human myo-inositol monophosphatase gene, IMP.18p, maps to a susceptibility region for bipolar disorder. (PubMed id 9322233)1, 2, 3, 9 Yoshikawa T....Detera-Wadleigh S.D. (1997)
- Crystal structure of human myo-inositol monophosphatase 2, the product of the putative susceptibility gene for bipolar disorder, schizophrenia, and febrile seizures. (PubMed id 17340635)1, 2, 9 Arai R.... Yokoyama S. (2007)
- A promoter haplotype of the inositol monophosphatase 2 gene (IMPA2) at 18p11.2 confers a possible risk for bipolar disorder by enhancing transcription. (PubMed id 17251911)1, 7, 9 Ohnishi T....Yoshikawa T. (2007)
- A human myo-inositol monophosphatase gene (IMPA2) localized in a putative susceptibility region for bipolar disorder on chromosome 18p11.2: genomic structure and polymorphism screening in manic- depressive patients. (PubMed id 10822345)1, 2, 9 Sjoholt G....Steen V.M. (2000)
- Evidence for association of the myo-inositol monophosphatase 2 (IMPA2) gene with schizophrenia in Japanese samples. (PubMed id 11317223)1, 4, 9 Yoshikawa T....Detera-Wadleigh S.D. (2001)
- Association study of myo-inositol monophosphatase 2 (IMPA2) polymorphisms with bipolar affective disorder and response to lithium treatment. (PubMed id 15505643)1, 4, 9 Dimitrova A....Kirov G. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Lithium modulation of the human inositol monophosphatase 2 (IMPA2) promoter. (PubMed id 15504365)2, 9 Seelan R.S.... Parthasarathy R.N. (2004)
- Examination of IMPA1 and IMPA2 genes in manic-depressive patients: association between IMPA2 promoter polymorphisms and bipolar disorder. (PubMed id 14699425)1, 9 Sjoholt G....Steen V.M. (2004)
|
External Searches for IMPA2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing IMPA2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing IMPA2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing IMPA2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for IMPA2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for IMPA2 gene:
Search GeneIP for patents involving IMPA2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for IMPA2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for IMPA2 | | OriGene shRNA RFP for IMPA2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IMPA2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IMPA2 | | | OriGene Protein Over-expression Lysate for IMPA2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for IMPA2 | | OriGene 3'-UTR Clone for IMPA2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IMPA2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IMPA2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for IMPA2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for IMPA2 | | OriGene Custom Protein Services for IMPA2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IMPA2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IMPA2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IMPA2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IMPA2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IMPA2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IMPA2 |
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| | | | Search Tocris compounds for IMPA2 |
| |  |  |  |  | | | | | | Recombinant Protein for IMPA2 |
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 | | | IMPA2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IMPA2 |
|  |  |  | | | | ThermoFisher Antibody for IMPA2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IMPA2 |
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