IDH3A Gene
protein-coding GIFtS: 61
GCID: GC15P078423
|
|
isocitrate dehydrogenase 3 (NAD+) alpha
| |
Aliases
for IDH3A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Isocitrate Dehydrogenase 3 (NAD+) Alpha1 2 | | Isocitrate Dehydrogenase (NAD+) Alpha Chain2 | | Isocitric Dehydrogenase Subunit Alpha2 3 | | Isocitrate Dehydrogenase [NAD] Subunit Alpha, Mitochondrial2 | | NAD(+)-Specific ICDH Subunit Alpha2 3 | | NAD(H)-Specific Isocitrate Dehydrogenase Alpha Subunit2 | | EC 1.1.1.413 8 | | NAD+-Specific ICDH2 | | H-IDH Alpha2 | | EC 1.1.18 |
Export aliases for IDH3A gene to outside databasesPrevious GC identifers: GC15P074520 GC15P071531 GC15P076017 GC15P076157 GC15P076228 GC15P078441 GC15P055199 |
Summaries
for IDH3A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for IDH3A:
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belongto two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Fiveisocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to themitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the otherpredominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulatedrate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alphasubunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of oneisozyme of NAD(+)-dependent isocitrate dehydrogenase. (provided by RefSeq, Jul 2008)
Gene Wiki entry for IDH3A
|
Genomic Views
for IDH3A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the IDH3A gene promoter:
NF-1 NF-1/L STAT1 GCNF STAT1beta AP-2gamma YY1 STAT1alpha GCNF-1 GCNF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for IDH3A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IDH3A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q25.1-q25.2 Ensembl cytogenetic band: 15q25.1 HGNC cytogenetic band: 15q25.1-q25.2IDH3A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15P078423: view genomic region
(about GC identifiers)
Start:
|
78,423,840 bp from pter |
End:
|
78,464,291 bp from pter |
Size:
|
40,452 bases |
Orientation:
|
plus strand |
|
Proteins
for IDH3A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: IDH3A_HUMAN, P50213 (See
protein sequence)Recommended Name: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor Size: 366 amino acids; 39592 Da
Cofactor: Binds 1 magnesium or manganese ion per subunit (By similarity)
Subunit: Heterooligomer of subunits alpha, beta, and gamma in the apparent ratio of 2:1:1 (By similarity)
Subcellular location: Mitochondrion
Secondary accessions: D3DW83 Q9H3X0Alternative splicing: 2 isoforms: P50213-1 P50213-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for IDH3A: NX_P50213
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P50213
4/17 DME Specific Peptides for IDH3A (P50213) (see all 17)
IDH3A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_005521.1
ENSEMBL proteins: ENSP00000299518 ENSP00000452620 ENSP00000453084 ENSP00000453033 ENSP00000453480 ENSP00000453747 ENSP00000452754 ENSP00000453192 ENSP00000453903 ENSP00000453438 ENSP00000453222 ENSP00000453992 ENSP00000453338 ENSP00000453989 ENSP00000453008 ENSP00000453795 ENSP00000453459 ENSP00000387506 Reactome Protein details: P50213
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005739 | mitochondrion |
IDA | -- | | GO:0005759 | mitochondrial matrix |
TAS | -- |
IDH3A for ontologies About GeneDecksing
IDH3A Antibody Products:
Assay Products for IDH3A: |
Protein
Domains /
Families
for IDH3A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
IDH3A for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P50213ProtoNet protein and cluster: P50213 1 Blocks protein family: IPB001804 Isocitrate/isopropylmalate dehydrogenase
UniProtKB/Swiss-Prot: IDH3A_HUMAN, P50213Similarity: Belongs to the isocitrate and isopropylmalate dehydrogenases family |
Function
for IDH3A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: IDH3A_HUMAN, P50213Catalytic activity: Isocitrate + NAD(+) = 2-oxoglutarate + CO(2) + NADH Genatlas biochemistry entry for IDH3A:isocitrate dehydrogenase 3,alpha subunit,NADH dependent,mitochondrial matrix,catalyzing the third step of citric acidcycle
Enzyme Numbers (IUBMB): EC 1.1.1.411 2 EC 1.1.12
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IDH3A (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IDH3A (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: IDH3A (NM_005530) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IDH3A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IDH3A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IDH3A |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000287 | magnesium ion binding |
IEA | -- | | GO:0004449 | isocitrate dehydrogenase (NAD+) activity |
IEA | -- | | GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
-- | -- | | GO:0051287 | NAD binding |
IEA | -- |
IDH3A for ontologies About GeneDecksing
|
Pathways & Interactions
for IDH3A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | TCA Cycle | | | 2 | Metabolism | | | 3 | TCA cycle II (eukaryotic) | | | 4 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for IDH3A
4 
Reactome Pathways for IDH3A
2 
Kegg Pathways (Kegg details for IDH3A):
IDH3A for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IDH3A
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/179 Interacting proteins for IDH3A (P502132, 3 ENSP000002995184) via UniProtKB, MINT, STRING, and/or I2D (see all 179)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
IDH3A for ontologies About GeneDecksing
|
Drugs & Compounds
for IDH3A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for IDH3A
7 HMDB Compounds for IDH3A About this table
1 DrugBank Compound for IDH3A About this table
Search CenterWatch for drugs/clinical trials and news about IDH3A
|
Transcripts
for IDH3A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for IDH3A gene: NM_005530.2 Unigene Cluster for IDH3A: Isocitrate dehydrogenase 3 (NAD+) alpha Hs.591110 [show with all ESTs]Unigene Representative Sequence: AK12331618/24 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 24): ENST00000558605 ENST00000299518(uc002bdd.3 uc010umt.2 uc010umu.2 uc002bdf.3 uc010umv.2 uc021srf.1)
ENST00000558933 ENST00000558554 ENST00000560667 ENST00000557826 ENST00000561279
ENST00000559186 ENST00000560396 ENST00000560770 ENST00000559865 ENST00000559881
ENST00000558509 ENST00000559889 ENST00000559803 ENST00000559205 ENST00000560414
ENST00000559106
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IDH3A (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IDH3A (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: IDH3A (NM_005530) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IDH3A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IDH3A |
Additional cDNA sequence: AK093531.1 AK096721.1 AK123316.1 AK222973.1 AK296002.1 AK299970.1 AK315963.1 AK316051.1 AL110096.1 AL442090.1 BC021967.2 BC036227.1 CR749548.1 U07681.1 24/26 DOTS entries (see all 26): DT.86855063 DT.99945419 DT.100824942 DT.100824943 DT.100824944 DT.95258957 DT.100824933 DT.92443593 DT.91830964 DT.100824945 DT.100027192 DT.95197969 DT.95363838 DT.121032158 DT.121032190 DT.121032180 DT.430952 DT.100027191 DT.121032125 DT.121032155 DT.121032166 DT.100714103 DT.100824938 DT.101983174 24/340 AceView cDNA sequences (see all 340): CA450355 AU160420 BC021967 AI292132 CA430498 BM929284 BP363836 BM719480 AL043545 AI095654 BE550193 AI802723 BM838562 BI764481 AW305302 BI261860 BP372914 AL442090 BQ636491 BF111986 AW849611 AA911181 CB216934 BE273577
GeneLoc Exon Structure
5/20 Alternative Splicing Database (ASD) splice patterns (SP) for IDH3A (see all 20) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | · | 11c | ^ | 12a | · | 12b | · | 12c | · | 12d | · | 12e | ^ |
|---|
|
| SP1: | | | | | | | - | | - | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | - | | | | | | - | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | - | | | | | | - | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | - | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | - | | - | | - | | | | | | - | | | | | | | | | | | | - | | | | | | - | | - | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | - | | | | | | - | | - | | | | | | | |
| ExUns: | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b |
|---|
|
| SP1: | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | |
ECgene alternative splicing isoforms for IDH3A
|
Expression
for IDH3A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| IDH3A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCCTCCTTTG
About this image
See IDH3A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IDH3A
SOURCE GeneReport for Unigene cluster: Hs.591110
SABiosciences Expression via Pathway-Focused PCR Arrays including IDH3A:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IDH3A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IDH3A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IDH3A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IDH3A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IDH3A |
Orthologs
for IDH3A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for IDH3A gene from 10/44 species (see all 44) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
IDH3A1 |
isocitrate dehydrogenase 3 (NAD+) alpha |
80.9(n)
91.18(a) |
|
415362 NM_001005808.1 NP_001005808.1 |
lizard
(Anolis carolinensis) |
Reptilia |
IDH3A6 |
-- |
83(a) |
1 ↔ 1 |
GL343486.1(123175-135305) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.159522 |
Xenopus laevis transcribed sequence with moderate similarity more |
78.32(n) |
|
BU913373.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc563802 |
similar to isocitrate dehydrogenase 3 (NAD+) alpha |
77.55(n) |
|
393926 BC049011.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG122333
l(1)G01561 |
isocitrate dehydrogenase (NAD+)3
lethal (1) G01561 |
71(a)
(best of 2)3
64.6(n)1
71.3(a)1 |
|
18C83
329401 NM_167657.21 NP_728257.21 |
worm
(Caenorhabditis elegans) |
Secernentea |
F43G9.13
idha-11 |
isocitrate dehydrogenase3
Protein IDHA-11 |
65(a)3
63.08(n)1
70.54(a)1 |
|
I(8614990-8616683)3
1726551 NM_059929.21 NP_492330.21 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
IDH2(YOR136W)4
IDH21 |
Subunit of mitochondrial NAD(+)-dependent isocitrate more4
Idh2p1 |
54.48(n)1
56.5(a)1 |
|
15(580250-581359)4
8543031, 4 NP_014779.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
IDH-VI1 |
Isocitrate dehydrogenase [NAD] catalytic subunit 6 |
60.1(n)
57.23(a) |
|
820139 NM_180218.1 NP_850549.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.2072 |
Oryza sativa (japonica cultivar-group) cDNA clone0 more |
74.77(n) |
|
AK059596.1 |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
leuB6dmlA6(see all 3) |
3-isopropylmalate dehydrogenase, NAD(+)-dependentD-malate oxidase, NAD-dependent; probable tartrate...(see all 3) |
30(a)29(a)(see all 3) |
possible orthologpossible ortholog(see all 3) |
Chromosome(80867-81958) Chromosome(1879936-1881021) |
ENSEMBL Gene Tree for IDH3A (if available)
TreeFam Gene Tree for IDH3A (if available) |
Paralogs
for IDH3A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for IDH3A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for IDH3A (78423840 - 78464291 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for IDH3A: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IDH3A |
|
Disorders
/ Diseases
for IDH3A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 IDH3A for disorders About MalaCards
IDH3A for disorders About GeneDecksing
OMIM gene information: 601149
OMIM disorders: --
Human Genome Epidemiology (HuGE) Navigator: IDH3A (2 documents)
Export disorders for IDH3A gene to outside databases
|
Publications
for IDH3A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for IDH3A gene, integrated from 9 sources (see all 36):
(articles sorted by number of sources associating them with IDH3A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of a cDNA clone for human NAD(+)-specific isocitrate dehydrogenase alpha-subunit and structural comparison with its isoenzymes from different species. (PubMed id 7755589)1, 2, 9 Kim Y.O.... Huh T.L. (1995)
- Assignment of the human mitochondrial NAD+ -specific isocitrate dehydrogenase alpha subunit (IDH3A) gene to 15q25.1-->q25.2by in situ hybridization. (PubMed id 8833160)1, 3, 9 Huh T.L....Inazawa J. (1996)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- A Three-Stage Genome-Wide Association Study of Genera l Cognitive Ability: Hunting the Small Effects. (PubMed id 20306291)1 Davis O.S....Plomin R. (2010)
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External Searches for IDH3A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing IDH3A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing IDH3A gene
(According to HUGE)
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Specialized Databases showing IDH3A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for IDH3A | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for IDH3A gene:
Search GeneIP for patents involving IDH3A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for IDH3A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | OriGene Antibodies for IDH3A | | OriGene shRNA RFP for IDH3A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IDH3A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IDH3A | | | OriGene Protein Over-expression Lysate for IDH3A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for IDH3A | | OriGene 3'-UTR Clone for IDH3A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IDH3A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IDH3A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for IDH3A | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for IDH3A | | OriGene Custom Protein Services for IDH3A | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IDH3A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IDH3A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IDH3A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IDH3A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IDH3A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IDH3A |
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| | | | Search Tocris compounds for IDH3A |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IDH3A |
|  |  |  | | | | ThermoFisher Antibodies for IDH3A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IDH3A |
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