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GRIN3A Gene

protein-coding GIFtS: 59

GC09M103371

glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
FLJ45414 ^²
KIAA1973 ^³
NMDAR-L ^², ³
NR3A ^², ⁵
OTTHUMP00000021814 ^²

Descriptions
N-methyl-D-aspartate receptor subtype NR3A ^³
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A ^²

External Ids
HGNC: 16767¹
Entrez Gene: 116443²
UniProtKB: Q8TCU5³
Ensembl: ENSG00000198785⁷

Search outside databases for aliases for GRIN3A gene

Previous GC identifers: GC09M095131 GC09M096075 GC09M097789 GC09M099711 GC09M101411

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for GRIN3A:

This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the

superfamily of glutamate-regulated ion channels, and function in physiological and pathological

processes in the central nervous system. This subunit shows greater than 90% identity to the

corresponding subunit in rat. Studies in the knockout mouse deficient in this subunit suggest that

this gene may be involved in the development of synaptic elements by modulating NMDA receptor

activity. [provided by RefSeq]

UniProtKB/Swiss-Prot: NMD3A_HUMAN, Q8TCU5

Function: NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel

conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated

by glycine. May play a role in the development of dendritic spines. May play a role in

PPP2CB-NMDAR mediated signaling mechanism (By similarity)

Gene Wiki entry for GRIN3A

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the GRIN3A gene

Entrez Gene cytogenetic band: 9q31.1 Ensembl cytogenetic band: 9q31.1 HGNC cytogenetic band: 9q

GRIN3A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 9 GeneLoc Exon Structure

GeneLoc location for GC09M103371: (about GC identifiers)

Start:	103,371,456 bp from pter
End:	103,540,683 bp from pter
Size:	169,228 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000009.10 NT_008470.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: NMD3A_HUMAN, Q8TCU5 (See protein sequence)

Recommended Name: Glutamate [NMDA] receptor subunit 3A precursor

Size: 1115 amino acids; 125465 Da

Subunit: Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B,

GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). Does not form functional homomeric

channels. Found in a complex with GRIN1, GRIN2A or GRIN2B and PPP2CB. Probably interacts with

PPP2CB. No complex with PPP2CB is detected when NMDARs are stimulated by NMDA (By similarity)

Subcellular location: Cell membrane; Multi-pass membrane protein (By similarity). Cell junction,

synapse, postsynaptic cell membrane (By similarity). Cell junction, synapse, postsynaptic cell

membrane, postsynaptic density (By similarity). Note=Enriched in post-synaptic plasma membrane and

post-synaptic densities. Requires the presence of GRIN1 to be targeted at the plasma membrane (By

similarity)

Developmental stage: Expressed in fetal brain

Secondary accessions: B3DLF9 Q5VTR3 Q8TF29 Q8WXI6

Post-translational modifications:

N-glycosylated (By similarity)¹

REFSEQ proteins: NP_597702.2

ENSEMBL proteins:

ENSP00000355155

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (NR3A, NMDAR3A + 3B)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5/8 Gene Ontology (GO) cellular component terms (links to tree view) (see all 8 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0016021	integral to membrane	NAS	11880201
GO:0017146	N-methyl-D-aspartate selective glutamate receptor complex	IDA	17997397
GO:0030054	cell junction	IEA	--
GO:0043005	neuron projection	IDA	17658481

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Antibodies for GRIN3A:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of GRIN3A
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (NR3A, NMDAR3A + 3B), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for GRIN3A

Assays for GRIN3A:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q8TCU5

ProtoNet protein and cluster: Q8TCU5

2 Blocks protein families:

IPB001320 Ionotropic glutamate receptor

IPB001508 NMDA receptor signature

UniProtKB/Swiss-Prot: NMD3A_HUMAN, Q8TCU5

Similarity: Belongs to the glutamate-gated ion channel (TC 1.A.10) family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (GRIN3A)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (GRIN3A)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_133445

Applied Biosystems Silencer® siRNAs for GRIN3A

Sigma-Aldrich siRNA and siRNA Panels for GRIN3A

Sigma-Aldrich shRNA for GRIN3A

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for GRIN3A
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_133445
Myc/DDK tagged cDNA clone in CMV expression vector: NM_133445
untagged cDNA clone in CMV expression vector: NM_133445

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_133445

UniProtKB/Swiss-Prot: NMD3A_HUMAN, Q8TCU5

Function: NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel

conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated

by glycine. May play a role in the development of dendritic spines. May play a role in

PPP2CB-NMDAR mediated signaling mechanism (By similarity)

4 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Grin3a):

behavior/neurological

nervous system

normal

vision/eye

5/10 Gene Ontology (GO) molecular function terms (links to tree view) (see all 10 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000287	magnesium ion binding	IEA	--
GO:0004872	receptor activity	IEA	--
GO:0004972	contributes to N-methyl-D-aspartate selective glutamate receptor activity	ISS	--
GO:0005216	ion channel activity	IEA	--
GO:0005234	extracellular-glutamate-gated ion channel activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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4 Sigma-Aldrich "Your Favorite Gene" Pathways for GRIN3A (Your Favorite Gene powered by Ingenuity)

Amyotrophic Lateral Sclerosis Signaling
Calcium Signaling
Synaptic Long Term Potentiation
Neuropathic Pain Signaling In Dorsal Horn Neurons

GeneDecks GRIN3A for the pathways selected above

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Gene Network Central^TM Interacting Genes and Proteins Network for GRIN3A

5/12 Interacting proteins for GRIN3A (ENSP00000355155³) via UniProtKB, MINT, and/or STRING (see all 12 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GRIN1	ENSP00000360616³	STRING (score=.989)
GRIN2A	ENSP00000332549³	STRING (score=.97)
GRIN2B	ENSP00000279593³	STRING (score=.969)
MAP1S	ENSP00000325313³	STRING (score=.918)
GRIN3B	ENSP00000234389³	STRING (score=.905)

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5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006811	ion transport	IEA	--
GO:0006816	calcium ion transport	ISS	--
GO:0016358	dendrite development	IEA	--
GO:0045471	response to ethanol	IDA	17502428 18445116
GO:0060134	prepulse inhibition	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Enzo Life Sciences drugs & compounds for GRIN3A

Sigma-Aldrich Small Molecules for GRIN3A:

Antagonist

Compounds for GRIN3A available from Tocris Bioscience

Compound	Action	CAS number
(+)-MK 801 maleate	Non-competitive NMDA antagonist, acts at ion channel site	[77086-22-7]
D-AP5	More active form of DL-AP5 (Cat. No. 0105)	[79055-68-8]
NMDA	Selective NMDA agonist	[6384-92-5]
SDZ 220-581	Competitive NMDA antagonist	[174575-17-8]
L-701,324	NMDA antagonist, acts glycine site	[142326-59-8]

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1 Novoseek chemical compound relationship for GRIN3A gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
calcium	2.53	1	18296432 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (GRIN3A)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (GRIN3A)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_133445

Sigma-Aldrich siRNA and siRNA Panels for GRIN3A

Sigma-Aldrich shRNA for GRIN3A

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_133445

REFSEQ mRNAs for GRIN3A gene:

NM_133445.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_133445

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_133445
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_133445
                                 untagged cDNA clone in CMV expression vector: NM_133445

Additional cDNA sequence:

AB075853.1 AF416558.1 AJ416950.2 AK125562.1 AK127342.1 AL137422.1 AL359651.1 BC029757.1

BC132866.1 BC132868.1 BC167432.1

5 DOTS entries:

DT.303624 DT.91659709 DT.101980616 DT.101958359 DT.75138664

20 AceView cDNA sequences:

NM_133445 AB075853 BX643290 Z44549 BF791640 Z40440 AL137422 BX282046

AL359651 F05465 BC029757 AK127342 BF969398 AW166288 AJ416950 AF416558

BQ930853 R61128 AW956215 AI613310

highest scoring ESTs for GRIN3A:

AB075853 AF416558 AJ416950 AL137422 AL359651 BC029757 BF791640 BQ930853 BX099698 BX282046

Unigene Cluster for GRIN3A:

Glutamate receptor, ionotropic, N-methyl-D-aspartate 3A

Hs.654783 [show with all ESTs]

Unigene Representative Sequence: BC167432

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000361820

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

GRIN3A expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for GRIN3A

¹ / ² / ³

5 probe-sets matching GRIN3A gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
48885_at²^{, 3}	U95-B	1	1.00	1.00	1.00	1.00	R61847	0.40	1.00	0.76	1
233171_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AL359651	0.60	1.00	0.82	1
233220_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AL137422	0.60	1.00	0.82	1
233171_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
233220_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks GRIN3A for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GATGGATTAG

SOURCE GeneReport for Unigene cluster: Hs.654783

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for GRIN3A gene from 5 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	GRIN3A¹	--	glutamate receptor, ionotropic, N-methyl-D-aspartate more	92.88(n) 94.89(a)	474789 XM_532019.2 XP_532019.2
mouse (Mus musculus)	Grin3a⁵	4	glutamate receptor ionotropic, NMDA3A	--	BQ174802
chicken (Gallus gallus)	GRIN3A¹	--	glutamate receptor, ionotropic, N-methyl-D-aspartate more	77.54(n) 84.58(a)	769001 XM_001232181.1 XP_001232182.1
zebrafish (Danio rerio)	LOC564832¹	--	similar to glutamate receptor, ionotropic, N-methyl-D-aspartate more	63.96(n) 64.22(a)	564832 XM_688168.3 XP_693260.3
African malaria mosquito (Anopheles gambiae)	AgaP_AGAP005527¹	--	AGAP005527-PA	46.09(n) 37.5(a)	1276211 XM_315527.2 XP_315527.2

About this table Species with no ortholog for GRIN3A

ENSEMBL Gene Tree for GRIN3A

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for GRIN3A gene

GRIN3B²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/1165 NCBI SNPs in GRIN3A are shown (see all 1165 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 498)

AB	SNP ID	Valid	Chr 9 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1983812^1,2	A,C,F,H,O	103372864(-)	`ATCGGG/ATTTAC`	1	--	ut3¹		13		NA EU EA WA	1162
	rs7030238^1,2	A,C,F,H	103372316(+)	`AGCTCA/CTCTGA`	1	--	ut3¹ ese³		4		EU EA WA	418
	rs2067056^1,2	A,C,F,H	103541388(+)	`TACAGT/CGAAGT`	1	--	ng3¹		8		EU EA WA NA	780
	rs10989591^1,2	A,C,F,H	103488919(+)	`CTCCAC/TATTCT`	1	V/M	mis¹ ese³		7		EU EA WA NA	658
--	rs10989563^1,2	A,C,F	103425532(+)	`TGGATC/TATTCC`	1	D/N	mis¹		5		NA EU EA WA	480
	rs3739722^1,2	C,F,H	103375503(-)	`CATCCA/GGATCC`	1	Q/R	mis¹ ese³		13		EA NA EU WA	2548
	rs3824473^1,2	C,F,H	103374598(-)	`TAAGCG/AGAAAC`	1	--	ut3¹ ese³		12		EA NA EU WA	2478
	rs10512282^1,2	C,F,H	103374154(+)	`CCAGTT/GCATAG`	1	--	ut3¹		16		NS EU EA WA NA	1090
	rs16920487^1,2	F,H	103373205(+)	`AACCTA/TCTTCT`	1	--	ut3¹ ese³		7		NA EU EA WA	556
--	rs1337676^1,2	A,C	103540442(-)	`CTTCTC/TATCCC`	1	--	ut5¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for GRIN3A (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 606650

Human Genome Epidemiology Navigator: GRIN3A (5 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/60 PubMed articles for GRIN3A gene (see all 60 ):

Cloning and expression of the human NMDA receptor subunit NR3A. (PubMed id 11880201)^{1, 3, 4} Eriksson M.... Sundstroem E. (2002)
Nucleotide sequence, genomic organization, and chromosomal localization of genes encoding the human NMDA receptor subunits NR3A and NR3B. (PubMed id 11735224)^{1, 3, 4} Andersson O.... von Euler G. (2001)
Expression of the NR3A subunit of the NMDA receptor in human fetal brain. (PubMed id 14684485)^{3, 4} Mueller H.T. and Meador-Woodruff J.H. (2003)
Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PubMed id 11853319)^{3, 4} Nagase T....Ohara O. (2001)
An NMDA receptor signaling complex with protein phosphatase 2A. (PubMed id 11588171)^{3, 4} Chan S.F. and Sucher N.J. (2001)
Analysis of NR3A receptor subunits in human native NMDA receptors. (PubMed id 17997397)^{1, 3} Nilsson A....Sundstrom E. (2007)
On the role of NR3A in human NMDA receptors. (PubMed id 17617428)^{1, 3} Eriksson M....Sundstrom E. (2007)
Genetic variations of the NR3A subunit of the NMDA receptor modulate prefrontal cerebral activity in humans. (PubMed id 17214563)^{1, 3} Gallinat J....Winterer G. (2007)
Developmental regulation of the NMDA receptor subunits, NR3A and NR1, in human prefrontal cortex. (PubMed id 18296432)^{1, 3} Henson M.A....Philpot B.D. (2008)
Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. (PubMed id 19156168)³ Need A.C....Goldstein D.B. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 116443	HGNC: 16767	AceView: GRIN3A	Ensembl:ENSG00000198785	euGenes: HUgn116443
ECgene: GRIN3A	H-InvDB: GRIN3A

(According to HUGE)
About This Section

HUGE: KIAA1973

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for GRIN3A
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for GRIN3A:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for GRIN3A-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for GRIN3A		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for GRIN3A		Small molecules for GRIN3A
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Search for Recombinant Proteins
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	Chimera RNAi (GRIN3A)
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	Custom Service for Rabbit Pab from Full-length Protein

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	Recombinant Proteins (NR3A, NMDAR3A + 3B)
	Antibodies (NR3A, NMDAR3A + 3B)

Search OriGene for GRIN3A

Tocris compounds for GRIN3A

	Drugs for GRIN3A
	Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for GRIN3A

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GRIN3A Gene

protein-coding GIFtS: 59

Aliases &
Descriptions
for GRIN3A

Summaries
for GRIN3A

Genomic Location
for GRIN3A

Proteins
for GRIN3A

Protein Domains/
Families
for GRIN3A

Gene Function
for GRIN3A

Pathways & Interactions
for GRIN3A

Drugs & Compounds
for GRIN3A

Transcripts
for GRIN3A

Expression
for GRIN3A

Orthologs
for GRIN3A

Paralogs
for GRIN3A

SNPs/Variants
for GRIN3A

Disorders & Mutations
for GRIN3A

Medical News
for GRIN3A

Publications
for GRIN3A

Search for GRIN3A

Genome Databases showing GRIN3A

Other Databases showing GRIN3A

Specialized Databases showing GRIN3A

Licensable Technologies
for GRIN3A

Services
for GRIN3A

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

GRIN3A Gene

protein-coding GIFtS: 59

Aliases & Descriptionsfor GRIN3A

Summariesfor GRIN3A

Genomic Locationfor GRIN3A

Proteinsfor GRIN3A

Protein Domains/Familiesfor GRIN3A

Gene Functionfor GRIN3A

Pathways & Interactionsfor GRIN3A

Drugs & Compoundsfor GRIN3A

Transcriptsfor GRIN3A

Expression for GRIN3A

Orthologsfor GRIN3A

Paralogsfor GRIN3A

SNPs/Variantsfor GRIN3A

Disorders & Mutationsfor GRIN3A

Medical Newsfor GRIN3A

Publicationsfor GRIN3A

Search for GRIN3A

Genome Databases showing GRIN3A

Other Databases showing GRIN3A

Specialized Databases showing GRIN3A

Licensable Technologiesfor GRIN3A

Servicesfor GRIN3A

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for GRIN3A

Summaries
for GRIN3A

Genomic Location
for GRIN3A

Proteins
for GRIN3A

Protein Domains/
Families
for GRIN3A

Gene Function
for GRIN3A

Pathways & Interactions
for GRIN3A

Drugs & Compounds
for GRIN3A

Transcripts
for GRIN3A

Expression
for GRIN3A

Orthologs
for GRIN3A

Paralogs
for GRIN3A

SNPs/Variants
for GRIN3A

Disorders & Mutations
for GRIN3A

Medical News
for GRIN3A

Publications
for GRIN3A

Licensable Technologies
for GRIN3A

Services
for GRIN3A