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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GPR17 Gene

protein-coding   GIFtS: 57
GCID: GC02P128403

G protein-coupled receptor 17
 Explore 4 diseases affiliated with
GPR17 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for GPR17    

Aliases
for GPR17 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
G Protein-Coupled Receptor 171 2
R122 3
G-Protein Coupled Receptor 172 3
P2Y-Like Receptor2 3
UDP/CysLT Receptor2 3
Uracil Nucleotide/Cysteinyl Leukotriene Receptor2

External Ids:    HGNC: 44711   Entrez Gene: 28402   Ensembl: ENSG000001442307   OMIM: 6030715   UniProtKB: Q133043   

Export aliases for GPR17 gene to outside databases

Previous GC identifers: GC02P125701 GC02P126328 GC02P128308 GC02P128497 GC02P128119 GC02P120709


Summaries
for GPR17 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: GPR17_HUMAN, Q13304
Function: Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i)
and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia

Gene Wiki entry for GPR17


Genomic Views
for GPR17 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_022135.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GPR17 gene promoter:
         c-Fos   AP-1   Pax-5   Lmo2   NF-kappaB   HEN1   NF-kappaB2   c-Jun   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: GPR17 promoter sequence
   Search SABiosciences Chromatin IP Primers for GPR17

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GPR17


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q21   Ensembl cytogenetic band:  2q14.3   HGNC cytogenetic band: 2q21

GPR17 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GPR17 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P128403:  view genomic region     (about GC identifiers)

Start:
 128,403,439 bp from pter      End:
 128,410,213 bp from pter
Size:
 6,775 bases      Orientation:
 plus strand

Proteins
for GPR17 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: GPR17_HUMAN, Q13304 (See protein sequence)
Recommended Name: Uracil nucleotide/cysteinyl leukotriene receptor  
Size: 367 amino acids; 40989 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Secondary accessions: A8K9L0 B2R9X0 Q8N5S7 Q9UDZ6 Q9UE21
Alternative splicing: 2 isoforms:  Q13304-1   Q13304-2   

Explore the universe of human proteins at neXtProt for GPR17: NX_Q13304

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q13304

    • GPR17 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (4 alternative transcripts): 
    NP_001154887.1  NP_001154888.1  NP_001154889.1  NP_005282.1  

    ENSEMBL proteins: 
     ENSP00000272644   ENSP00000387970   ENSP00000376741   ENSP00000442982  
    Reactome Protein details: Q13304
    Human Recombinant Protein Products: 
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    Novus Biologicals GPR17 Protein
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for GPR17

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral to plasma membrane TAS8558062
    GO:0016021integral to membrane ----


    GPR17 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for GPR17 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    GPR17 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR002286 P2_purnocptor
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry Q13304

    ProtoNet protein and cluster: Q13304

    1 Blocks protein family: IPB002286 P2 purinoceptor signature

    UniProtKB/Swiss-Prot: GPR17_HUMAN, Q13304
    Similarity: Belongs to the G-protein coupled receptor 1 family


    Function
    for GPR17 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: GPR17_HUMAN, Q13304
    Function: Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i)
    and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmid: GPR17 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: GPR17
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004950chemokine receptor activity TAS8558062
    GO:0045028G-protein coupled purinergic nucleotide receptor activity IEA--


    GPR17 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for GPR17:
     Increased circadian period len 

    Animal Models:
         3 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Gpr17):
     behavior/neurological  cardiovascular system  nervous system 

    GPR17 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for GPR17 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Class A/1 (Rhodopsin-like receptors)
    		Class A/1 (Rhodopsin-like receptors)1.00
    		G alpha (i) signalling events0.44
    		GPCR ligand binding0.75
    		GPCRs, Class A Rhodopsin-like0.41
    2Signaling by GPCR
    		Signaling by GPCR1.00
    		Signal Transduction0.56
    		GPCR downstream signaling0.89
    3Nucleotide-like (purinergic) receptors
    		Nucleotide-like (purinergic) receptors1.00
    		P2Y receptors0.75
    4G alpha (q) signalling events
    		G alpha (q) signalling events1.00
    		Gastrin-CREB signalling pathway via PKC and MAPK0.90
    5Prostanoid ligand receptors
    		Eicosanoid ligand-binding receptors0.60
    		Leukotriene receptors0.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    2 BioSystems Pathways for GPR17 
        GPCRs, Class A Rhodopsin-like
    GPCRs, Other

    5/12        Reactome Pathways for GPR17 (see all 12)
        GPCR downstream signaling
    Eicosanoid ligand-binding receptors
    P2Y receptors
    Leukotriene receptors
    Gastrin-CREB signalling pathway via PKC and MAPK



    GPR17 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GPR17

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/247 Interacting proteins for GPR17 (Q133043 ENSP000002726444) via UniProtKB, MINT, STRING, and/or I2D (see all 247)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GNA13Q143443, ENSP000004007174I2D: score=2 STRING: ENSP00000400717
    ADCY1ENSP000002973234STRING: ENSP00000297323
    ADCY2ENSP000003429524STRING: ENSP00000342952
    APLNRENSP000002572544STRING: ENSP00000257254
    CCKENSP000003356574STRING: ENSP00000335657
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway TAS8558062
    GO:0070098chemokine-mediated signaling pathway TAS8558062


    GPR17 for ontologies           About GeneDecksing



    Drugs & Compounds
    for GPR17 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GPR17

    1 HMDB Compound for GPR17    About this table
    CompoundSynonyms CAS #PubMed Ids
    Uracil2,4-Dihydroxypyrimidine (see all 8)66-22-8--
    Search CenterWatch for drugs/clinical trials and news about GPR17 

    Transcripts
    for GPR17 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for GPR17 gene (4 alternative transcripts): 
    NM_001161415.1  NM_001161416.1  NM_001161417.1  NM_005291.2  

    Unigene Clusters for GPR17:

    G protein-coupled receptor 17
    Hs.46453  [show with all ESTs], Hs.736277  [show with all ESTs]
    Unigene Representative Sequences: AK126849, BX538082
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000496086 ENST00000486700 ENST00000272644 ENST00000423019 ENST00000393018
    ENST00000544369(uc010yzn.2 uc002tpc.3 uc010yzo.2 uc002tpd.3)


    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate GPR17:
    hsa-miR-9*
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    Inhib. RNA
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    Clone
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    Primer
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    Additional cDNA sequence: BX538082.1 

    9 DOTS entries:

    DT.92428447  DT.114539  DT.101985303  DT.40125549  DT.105541  DT.121020343  DT.91875438  DT.100024465 
    DT.454095 

    24/123 AceView cDNA sequences (see all 123):

    BF527616 BG912322 AA862286 BG820495 BG818500 AA309544 AA297795 BF345843 
    BF345996 BC039595 N63411 BF345709 AI378784 Y12546 AI953187 BG911003 
    AI417819 NM_005291 BF530988 AI382504 BC013202 BF528803 BF347607 BX538082 

    GeneLoc Exon Structure


    Expression
    for GPR17 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GPR17 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACATCGATGT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    GPR17 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    6 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BoneZeugopod Epiphyseal EndChondrocytesBone, Cartilage
    Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor CellsMotor Neurons
    BoneZeugopod Growth PlateBone
    BrainMedulla OblongataBrain
    SomiteLumbar Vertebral BodySomite
    Spinal CordSpinal Ventral ColumnsSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See GPR17 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GPR17

    SOURCE GeneReport for Unigene clusters: Hs.46453 Hs.736277

    UniProtKB/Swiss-Prot: GPR17_HUMAN, Q13304
    Tissue specificity: Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain

        SABiosciences Expression via Pathway-Focused PCR Arrays including GPR17: 
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              Chemokines & Receptors in human mouse rat

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    In Situ
    Assay Products:     
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    Orthologs
    for GPR17 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for GPR17 gene from 3/10 species (see all 10)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves GPR171 G protein-coupled receptor 17 74.01(n)
    79.82(a)    		   769024  XM_001231869.1  XP_001231870.1 
    lizard
    (Anolis carolinensis)    		 Reptilia GPR176
    		 --
    		 76(a)
    		 1 ↔ 1
    		 3(36216950-36217966)
    zebrafish
    (Danio rerio)    		 Actinopterygii LOC1003318411 uracil nucleotide/cysteinyl leukotriene receptor-like 59.25(n)
    57.01(a)    		   100331841  XM_002662449.2  XP_002662495.2 


    ENSEMBL Gene Tree for GPR17 (if available)
    TreeFam Gene Tree for GPR17 (if available) 

    Paralogs
    for GPR17 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GPR17 gene
    P2RY42  CYSLTR12  LPAR42  CYSLTR22  P2RY22  PTAFR2  OXGR12  P2RY12  
    P2RY112  P2RY62  GPR1742  LPAR62  LPAR52  GPR1832  SUCNR12  P2RY102  
    18/49 SIMAP similar genes for GPR17 using alignment to 3 protein entries:     GPR17_HUMAN (see all proteins) (see all similar genes):
    DKFZp686M18273    CYSLTR1    P2RY1    LPAR4    CXCR7    CYSLTR2
    KPG_011    CCR-5    GPR183    LPAR6    P2RY5    CCR8
    GPR18    AGTR1    F2RL1    GPR171    GPR34    OPRK1

    GPR17 for paralogs           About GeneDecksing



    Genomic Variants
    for GPR17 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/257 NCBI SNPs in GPR17 are shown (see all 257)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 2 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1137915681,2
    		F--120715472(+) CGCCAC/TGCCCT 1 -- us2k11Minor allele frequency- T:0.50CSA 4
    rs344154891,2
    		C,F,--120715583(+) GGGGGC/AGCCGT 1 -- us2k11Minor allele frequency- A:0.13EU 606
    rs739546811,2
    		C,--120715844(+) AGGCCG/AGAAGA 1 -- us2k12Minor allele frequency- A:0.08WA 120
    rs754812941,2
    		--120715915(+) CAGAAA/TCGCTC 1 -- us2k10--------
    rs778942331,2
    		C,F,--120716001(+) GGGACG/AGGGAG 1 -- us2k11Minor allele frequency- A:0.05WA 118
    rs38212311,2
    		C,F,H,--120716047(-) GAGGGG/TACTCA 1 -- us2k1 ese36Minor allele frequency- T:0.04EA NS NA 1920
    rs118863841,2
    		C,F,H,--120716127(+) CCAGCG/AGACGT 1 -- us2k1 ese35Minor allele frequency- A:0.00NS EA NA 414
    rs608643201,2
    		--120716149(+) GCCTGC/TAGGGA 1 -- us2k10--------
    rs342045061,2
    		C,--120716415(+) TTTGTA/GTTTGT 1 -- us2k12Minor allele frequency- G:0.02NA EA 122
    rs785297861,2
    		--120716686(+) CCTTAC/TGGCAA 1 -- nc-transcript-variant1Minor allele frequency- T:0.01WA 118

    HapMap Linkage Disequilibrium report for GPR17 (128403439 - 128410213 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for GPR17
         2 CNVs: 50278 30103

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for GPR17 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    GPR17 for disorders           About GeneDecksing

    OMIM gene information: 603071    OMIM disorders: --

    4 diseases for GPR17:    About MalaCards
    spinal cord injury    suppression amblyopia    amblyopia    ischemia

    1 disease from the University of Copenhagen DISEASES database for GPR17:
    Suppression amblyopia

    Export disorders for GPR17 gene to outside databases

    Publications
    for GPR17 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GPR17 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with GPR17)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. New members of the chemokine receptor gene family. (PubMed id 8558062)1, 2, 3 Raport C.J.... Gray P.W. (1996)
    2. The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor. (PubMed id 16990797)1, 2 Ciana P.... Abbracchio M.P. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. A novel orphan G protein-coupled receptor primarily expressed in the brain is localized on human chromosomal band 2q21. (PubMed id 9523551)1, 2 Blaesius R.H.... Ogilvie A. (1998)
    5. Agonist-induced desensitization/resensitization of hu man G protein-coupled receptor 17: a functional cross-talk between purinergic a nd cysteinyl-leukotriene ligands. (PubMed id 21531793)1 Daniele S....Martini C. (2011)
    6. EBI2, GPR18 and GPR17--three structurally related, bu t biologically distinct 7TM receptors. (PubMed id 21261596)1 NA...Rosenkilde M.M. (2011)
    7. Distinct expression and ligand-binding profiles of tw o constitutively active GPR17 splice variants. (PubMed id 20148890)1 Benned-Jensen T. and Rosenkilde M.M. (2010)
    8. Functional characterization of two isoforms of the P2 Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells. (PubMed id 19625605)1 Pugliese A.M....Abbracchio M.P. (2009)
    9. GPR17: molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors. (PubMed id 18533035)1 Parravicini C....Fantucci P. (2008)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)

    External Searches for GPR17 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing GPR17 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2840 HGNC: 4471 AceView: GPR17 Ensembl:ENSG00000144230 euGenes: HUgn2840
    ECgene: GPR17 H-InvDB: GPR17

    Other Databases showing GPR17 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing GPR17 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GPR17 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for GPR17 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for GPR17 gene:
    Search GeneIP for patents involving GPR17

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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