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C13orf26 Gene

protein-coding   GIFtS: 37

GC13P030408
chromosome 13 open reading frame 26
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases
MGC40178 1, 2
OTTHUMP00000018207 2
Descriptions
chromosome 13 open reading frame 26 2
hypothetical protein LOC122046 2
External Ids
HGNC: 286221
Entrez Gene: 1220462
UniProtKB: Q8N6G23
Ensembl: ENSG000001756647
Search outside databases for aliases for C13orf26 gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  --
(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the C13orf26 gene  

Entrez Gene cytogenetic band: 13q12.3   Ensembl cytogenetic band:  13q12.3   HGNC cytogenetic band: 13q12.3

C13orf26 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P030408:     (about GC identifiers)

Start:
30,404,834 bp from pter
End:
30,447,153 bp from pter
Size:
42,320 bases
Orientation:
plus strand
RefSeq DNA sequence:
NC_000013.9  NT_024524.13  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: CM026_HUMAN, Q8N6G2 (See protein sequence)
Recommended Name: Uncharacterized protein C13orf26  
Size: 289 amino acids; 33595 Da

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_689538.1  

    ENSEMBL proteins: 
    ENSP00000369840 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse Abcam for Recombinant Proteins
    Browse Abnova for Human Recombinant Proteins
                  OriGene Purified Recombinant Human Protein: C13orf26 


    Antibodies for C13orf26: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse Antibodies at Sigma-Aldrich
    Browse R&D Systems for Antibodies
    Search for antibodies at Abcam and the World's Antibody Gateway (free search engine of over 150 antibody companies)
    Browse Abnova for Monoclonal and Polyclonal Antibodies
    Search Novus for antibodies for C13orf26

    Assays for C13orf26: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q8N6G2

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (C13orf26)
    Browse for Gene Knock-down Tools from Millipore
    Browse Abnova for Chimera RNAi Products
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_152325

                  Applied Biosystems Silencer® siRNAs for C13orf26

                  Sigma-Aldrich siRNA for C13orf26  
                         Browse shRNA at Sigma-Aldrich  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for C13orf26
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_152325
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_152325
                                     untagged cDNA clone in CMV expression vector: NM_152325 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_152325

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


      --
    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for C13orf26

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (C13orf26)
    Browse for Gene Knock-down Tools from Millipore
    Browse Abnova for Chimera RNAi Products
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_152325

                  Sigma-Aldrich siRNA for C13orf26  
                         Browse shRNA at Sigma-Aldrich  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_152325  

    REFSEQ mRNAs for C13orf26 gene: 

    NM_152325.1   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_152325  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_152325
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_152325
                                     untagged cDNA clone in CMV expression vector: NM_152325 

    Additional cDNA sequence: BC030277.1 

    4 DOTS entries:

    DT.100017963  DT.454291  DT.120772423  DT.99958208 

    20 AceView cDNA sequences:

    BC030277 AA382788 NM_152325 CB305402 AA382787 BI827089 BU609006 BX104527 
    AI204541 AA399237 AA774417 BG217246 AI025680 BG207087 AA412223 CD705608 
    BG198761 BG205892 BG216162 BG194205 

    highest scoring ESTs for C13orf26:

    AA399237 BC030277 BG217246 AA382787 AA412223 AA774417 AI025680 AI204541 BG194205 BG198761 

    Unigene Cluster for C13orf26:

    Chromosome 13 open reading frame 26
    Hs.124463  [show with all ESTs]
    Unigene Representative Sequence: BC030277


    GeneLoc Exon Structure

    1 Ensembl transcript including schematic representation:
    ENST00000380473  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    C13orf26 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for C13orf26

    1 / 2 / 3

    3 probe-sets matching C13orf26 gene


    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

    58875_at2, 3 U95-B 1 1.00 1.00 1.00 1.00 AA399237 0.80 1.00 0.91 1

    243884_at2, 3 U133-B 1 1.00 1.00 -- -- AI204541 0.60 1.00 0.82 1

    243884_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: --

    SOURCE GeneReport for Unigene cluster: Hs.124463
    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section


    Orthologs for C13orf26 gene from 5 species
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    LOC6079571   -- hypothetical protein LOC607957 81.34(n)
    73.24(a)
    607957  XM_844828.1  XP_849921.1 
    chimpanzee
    (Pan troglodytes)
    LOC4525211   -- similar to Chromosome 13 open reading frame 26 98.73(n)
    97.58(a)
    452521  XM_509614.2  XP_509614.2 
    cow
    (Bos taurus)
    C12H13ORF261   -- chromosome 13 open reading frame 26 ortholog 78.09(n)
    69.93(a)
    508945  XM_585801.3  XP_585801.3 
    rat
    (Rattus norvegicus)
    RGD15608461   -- similar to hypothetical protein MGC40178 72.41(n)
    62.92(a)
    498133  XM_573344.1  XP_573344.2 
    mouse
    (Mus musculus)
    4930588N13Rik1, 5 55
    RIKEN cDNA 4930588N13 gene1, 5 73.26(n)1
    62.27(a)1
    758601  XM_132524.61  XP_132524.31 
     AK0163695  AK0873195  (see all 10)
    About this table        Species with no ortholog for C13orf26

    ENSEMBL Gene Tree for C13orf26
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

      --
    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/324 NCBI SNPs in C13orf26 are shown (see all 324 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 112)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 13 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    rs95331681,2
    C,F,H30441068(+) ACAAAG/TAAACA 1 K/N mis18Minor allele frequency- T:0.00EU EA WA 838
    rs22973951,2
    C,F,H30403899(-) ACATGG/AGACCC 1 -- ng519Minor allele frequency- A:0.37EA EU WA 2138
    rs22973941,2
    C,F,H30404554(-) AAAAAG/AGGAAG 1 -- ng51 trp35Minor allele frequency- A:0.38EA EU WA 1904
    rs79816721,2
    C,F,H30403923(+) gagttC/Ggtatg 1 -- ng514Minor allele frequency- G:0.04EU EA WA 420
    rs22748691,2
    C,F,O30441095(-) TTGTCG/ATAGTC 1 Y/Y syn1 ese37Minor allele frequency- A:0.19EA NS NA 1604
    rs13318471,2
    A,C,F,H,O30433764(-) ACTCAG/ATGGAT 1 -- int116Minor allele frequency- A:0.50EU EA WA NA 1400
    rs18549501,2
    A,C,F,H,O30439510(-) GATACG/ACAGGG 1 -- int15Minor allele frequency- A:0.34MN EU EA WA 600
    rs19994211,2
    A,C,F,H,O30432962(-) GAATCG/AGCCTC 1 -- int14Minor allele frequency- A:0.44EU EA WA 390
    rs10020361,2
    A,C,F,H,O30405727(-) GGGAGC/AACAAT 1 -- int19Minor allele frequency- A:0.25NA EU EA WA 716
    rs28721941,2
    A,C,F,H30410404(-) CCAACT/CTCCCA 1 -- int14Minor allele frequency- C:0.41EU EA WA 418
    About this table

    HapMap Linkage Disequilibrium images for C13orf26 (up to first 250kb)

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

      --

    (Possibly Related Articles in Doctor's Guide)
    About This Section

      --

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    3 PubMed articles for C13orf26 gene:
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section

    Entrez Gene: 122046 HGNC: 28622 AceView: MGC40178 Ensembl:ENSG00000175664 euGenes: HUgn122046
    ECgene: C13orf26 H-InvDB: C13orf26
    (According to HUGE)
    About This Section

      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

      --
    (Available from WIS Yeda, Salk, Tufts)
    About This Section

      --
    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for C13orf26:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
      Free SNP selection tool



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     Search Novus for antibodies for C13orf26

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