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CYorf15A Gene

protein-coding   GIFtS: 38

GC0YP020117
chromosome Y open reading frame 15A
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
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Aliases &
Descriptions
for CYorf15A

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases
FLJ33216 2
MGC131732 2
Descriptions
chromosome Y open reading frame 15A 2
hypothetical protein LOC246126 2
External Ids
HGNC: 184731
Entrez Gene: 2461262
UniProtKB: Q9BZA53
Ensembl: ENSG000000997497
Search outside databases for aliases for CYorf15A gene

Previous GC identifers: GC0YP020933 GC0YM020925 GC0YP020624

Summaries
for CYorf15A

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

   --

Genomic Location
for CYorf15A

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the CYorf15A gene  

Entrez Gene cytogenetic band: Yq11.222   Ensembl cytogenetic band:  Yq11.222   HGNC cytogenetic band: Yq11.222

CYorf15A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome Y         GeneLoc Exon Structure

GeneLoc location for GC0YP020117:     (about GC identifiers)

Start:
 20,188,623 bp from pter
End:
 20,211,697 bp from pter
Size:
 23,075 bases
Orientation:
 plus strand
RefSeq DNA sequence:
NC_000024.8  NT_011875.11  

Proteins
for CYorf15A

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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 UniProtKB/Swiss-Prot: CY15A_HUMAN, Q9BZA5 (See protein sequence)
Recommended Name: Uncharacterized protein CYorf15A  
Size: 182 amino acids; 21481 Da
Miscellaneous: Products of an degenerate gene that is homologous to the 5'-portion of the X-linked
TXLNG gene

REFSEQ proteins: NP_001005852.2  

ENSEMBL proteins: 
ENSP00000384233 ENSP00000251749 


Human Recombinant Proteins 
Browse Drug Discovery Central at Invitrogen for human recombinant proteins
Browse Purified and Recombinant Proteins at Millipore
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Browse recombinant and purified proteins available from Enzo Life Sciences
Browse Abcam for Recombinant Proteins
Browse Abnova for Human Recombinant Proteins
                Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 


Antibodies for CYorf15A: 
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Search Novus for antibodies for CYorf15A

Assays for CYorf15A: 
Browse Invitrogen for biochemical assays
Browse Kits and Assays available from Millipore
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Protein Domains/
Families
for CYorf15A

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: Q9BZA5

UniProtKB/Swiss-Prot: CY15A_HUMAN, Q9BZA5
Similarity: Belongs to the taxilin family

Gene Function
for CYorf15A

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (CYorf15A)
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
              OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001005852

              Applied Biosystems Silencer® siRNAs for CYorf15A

              Sigma-Aldrich siRNA for CYorf15A  
                     Sigma-Aldrich shRNA for CYorf15A  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Clones:Browse Clone Ranger at Invitrogen for clones
Browse Clones for the Expression of Recombinant Proteins Available from Millipore
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001005852
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001005852
                                 untagged cDNA clone in CMV expression vector: NM_001005852 

Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
              OriGene genome-wide validated SYBR primer pairs: NM_001005852

Pathways & Interactions
for CYorf15A

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Interacting protein for CYorf15A (ENSP000002517493) via UniProtKB, MINT, and/or STRING
InteractantInteraction Details
GeneCardExternal ID(s)
CYorf15BENSP000002533203STRING (score=.837)
About this table

Drugs & Compounds
for CYorf15A

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences
Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for CYorf15A

Transcripts
for CYorf15A

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (CYorf15A)
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
              OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001005852

              Sigma-Aldrich siRNA for CYorf15A  
                     Sigma-Aldrich shRNA for CYorf15A  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Applied Biosystems Silencer® siRNAs: 

NM_001005852  

REFSEQ mRNAs for CYorf15A gene: 

NM_001005852.2   

Applied Biosystems TaqMan ® Gene Expression Assays: 

NM_001005852  

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001005852
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001005852
                                 untagged cDNA clone in CMV expression vector: NM_001005852 

Additional cDNA sequence: 

AF332224.1 AK090535.1 AK303404.1 BC110817.1 

10 DOTS entries:

DT.101981262  DT.206016  DT.107019  DT.97838710  DT.91726001  DT.95100334  DT.120653841  DT.97775092 
DT.101962998  DT.40285834 

24/115 AceView cDNA sequences (see all 115 ):

AI911501 AA876381 AA642399 BF062193 BF475922 AI494462 AA252353 AA741089 
BI757053 CA310501 AI478789 BM142473 AW294417 AA746374 AA262803 BF514384 
AW387371 AA912104 AW173005 BM263181 BC035312 BE350516 BQ228928 AA806034 

highest scoring ESTs for CYorf15A:

AI654057 AA465193 AF332224 AI129169 AI470516 AI761758 AI860134 AL697704 BM142473 BX481244 

Unigene Cluster for CYorf15A:

Chromosome Y open reading frame 15A
Hs.522863  [show with all ESTs]
Unigene Representative Sequence: AK090535


GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for CYorf15A (see all 7 )

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b
SP1:                    -     -     -     -           -     -     -                     
SP2:                          -     -     -           -     -     -                     
SP3:                                                  -                                 
SP4:                          -     -     -           -                                 
SP5:                    -     -     -     -           -                                 

About this scheme

ECgene alternative splicing isoforms for CYorf15A

2 Ensembl transcripts including schematic representations:
ENST00000407724  ENST00000251749  

Expression
for CYorf15A

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

CYorf15A expression in normal and diseased human tissues

 Applied Biosystems TaqMan ® Gene Expression Assays for CYorf15A

1 / 2 / 3

7 probe-sets matching CYorf15A gene


Affymetrix
probe-set		 Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

58427_at2, 3 U95-B 1 1.00 1.00 -0.04 0.35 AA504338 0.60 1.00 0.82 1

46058_r_at2, 3 U95-B 2 1.00 0.94 0.95 0.82 AI796007 0.60 1.00 0.82 1
58424_at2, 3 U95-B 2 1.00 0.94 0.95 1.19 AI654057 1.00 1.00 1.00 1

232618_at2, 3 U133-B 1 1.00 1.00 -- -- AF332224 0.80 1.00 0.91 1

236694_at2, 3 U133-B 1 1.00 1.00 -- -- AW468885 0.40 1.00 0.76 1

232618_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

236694_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
GeneDecks  CYorf15A for binary patterns associated with the probe-sets selected above  
About GeneDecksing
About this table    
Data from (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: TTGTAAATGC

SOURCE GeneReport for Unigene cluster: Hs.522863

UniProtKB/Swiss-Prot: CY15A_HUMAN, Q9BZA5
Tissue specificity: Ubiquitously expressed

Orthologs
for CYorf15A

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section
Orthologs for CYorf15A gene from 1 species
Organism Gene Locus Description Human
Similarity		 NCBI accessions
chimpanzee
(Pan troglodytes)		 CYorf15A1   -- chromosome Y open reading frame 15A 97.96(n)
96.18(a)		 450201  NM_001009080.1  NP_001009080.1 
About this table        Species with no ortholog for CYorf15A

ENSEMBL Gene Tree for CYorf15A

Paralogs
for CYorf15A

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section

  --

SNPs/Variants
for CYorf15A

(According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

  --

Disorders & Mutations
for CYorf15A

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

 OMIM: 400031

Medical News
for CYorf15A

(Possibly Related Articles in Doctor's Guide)
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   --

Publications
for CYorf15A

(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
About This Section

5 PubMed articles for CYorf15A gene:

Search for CYorf15A

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing CYorf15A

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section
Entrez Gene: 246126 HGNC: 18473 AceView: CYorf15BandCYorf15A Ensembl:ENSG00000099749 euGenes: HUgn246126
ECgene: CYorf15A H-InvDB: CYorf15A

Other Databases showing CYorf15A

(According to HUGE)
About This Section

   --

Specialized Databases showing CYorf15A

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

   --

Licensable Technologies
for CYorf15A

(Available from WIS Yeda, Salk, Tufts)
About This Section

  --

Services
for CYorf15A

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section



Products for CYorf15A:
 TaqMan ® Gene Expression Assays
 TaqMan ® Genotyping Assays
  Free SNP selection tool



  Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
  Invitrogen Antibodies  Invitrogen Assays
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  Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for CYorf15A-related products

 Millipore Custom Antibody & Bulk Services
 Millipore Preclinical / Clinical Development Services
 Millipore Immunoassay Services
 Millipore Target Screening & Profiling Services


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 Lentivirus-delivered shRNAs for CYorf15A Browse small molecules at Sigma-Aldrich
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 Search Novus for antibodies for CYorf15A

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