FNBP1 Gene
protein-coding GIFtS: 53
GCID: GC09M132649
|
|
formin binding protein 1
| |
Aliases
for FNBP1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Formin Binding Protein 11 2 | | FBP171 2 3 5 | | KIAA05541 3 | | Formin-Binding Protein 172 3 | | Formin-Binding Protein 12 | | HFBP171 |
Export aliases for FNBP1 gene to outside databasesPrevious GC identifers: GC09M124295 GC09M126103 GC09M128025 GC09M129730 GC09M131690 GC09M102248 |
Summaries
for FNBP1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for FNBP1:
The protein encoded by this gene is a member of the formin-binding-protein family. The protein contains an N-terminalFer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, asecond coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein bindssorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not beendemonstrated yet in human. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: FNBP1_HUMAN, Q96RU3Function: May act as a link between RND2 signaling and regulation of the actin cytoskeleton (By similarity). Requiredto coordinate membrane tubulation with reorganization of the actin cytoskeleton during the late stage ofclathrin-mediated endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserineand promotes membrane invagination and the formation of tubules. Also enhances actin polymerization via therecruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. Actin polymerization may promote the fissionof membrane tubules to form endocytic vesicles. May be required for the lysosomal retention of FASLG/FASL
Gene Wiki entry for FNBP1
|
Genomic Views
for FNBP1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008470.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FNBP1 gene promoter:
SRF SRF (504 AA) C/EBPalpha Max PPAR-gamma1 POU2F1 POU2F1a PPAR-gamma2 c-Myc Hlf
Other transcription factors
Search SABiosciences Chromatin IP Primers for FNBP1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FNBP1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q34 Ensembl cytogenetic band: 9q34.11 HGNC cytogenetic band: 9q34FNBP1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M132649: view genomic region
(about GC identifiers)
Start:
|
132,649,466 bp from pter |
End:
|
132,805,473 bp from pter |
Size:
|
156,008 bases |
Orientation:
|
minus strand |
|
Proteins
for FNBP1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FNBP1_HUMAN, Q96RU3 (See
protein sequence)Recommended Name: Formin-binding protein 1 Size: 617 amino acids; 71307 Da
Subunit: Interacts specifically with GTP-bound RND2 and CDC42. Interacts with PDE6G and microtubules (By similarity).Homodimerizes, the dimers can polymerize end-to-end to form filamentous structures. Interacts with AKAP9, ARHGAP17,DAAM1, DIAPH1, DIAPH2, DNM1, DNM2, DNM3, FASLG/FASL, SNX2 and WASL/N-WASP. May interact with TNKS
Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Lysosome. Cytoplasmic vesicle. Cellmembrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Note=Enriched in corticalregions coincident with F-actin. Also localizes to endocytic vesicles and lysosomes
Sequence caution: Sequence=AAH62463.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-Asequence; Sequence=AAK49824.1; Type=Erroneous initiation; Sequence=BAA25480.1; Type=Erroneous initiation;Sequence=BAA91451.1; Type=Erroneous initiation; Sequence=CAI12149.1; Type=Erroneous gene model prediction;Sequence=CAI12150.1; Type=Erroneous gene model prediction; Sequence=CAI13910.1; Type=Erroneous gene model prediction;Sequence=CAI13911.1; Type=Erroneous gene model prediction;
1 PDB 3D structure from  and Proteopedia  for FNBP1:2EFL (3D)
Secondary accessions: O60301 Q3MIN8 Q5TC87 Q5TC88 Q6P658 Q7LGG2 Q9H8H8 Q9NWD1Alternative splicing: 4 isoforms: Q96RU3-1 Q96RU3-2 Q96RU3-3 Q96RU3-4 Explore the universe of human proteins at neXtProt for FNBP1: NX_Q96RU3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96RU3
FNBP1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055848.1
ENSEMBL proteins: ENSP00000361493 ENSP00000415602 ENSP00000347907 ENSP00000413625 ENSP00000407548 ENSP00000389117
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
FNBP1 for ontologies About GeneDecksing
FNBP1 Antibody Products:
Assay Products for FNBP1: |
Protein
Domains /
Families
for FNBP1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FNBP1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96RU3ProtoNet protein and cluster: Q96RU3 2 Blocks protein families: IPB001060 Cdc15/Fes/CIP4 IPB001452 SH3 domain signature
UniProtKB/Swiss-Prot: FNBP1_HUMAN, Q96RU3Domain: The F-BAR domain binds the phospholipid membrane with its concave surface. The end-to-end polymerization ofdimers of these domains provides a curved surface that fits best membranes with around 600 A diameter, and may drivetubulationSimilarity: Belongs to the FNBP1 familySimilarity: Contains 1 FCH domainSimilarity: Contains 1 REM (Hr1) repeatSimilarity: Contains 1 SH3 domain |
Function
for FNBP1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: FNBP1_HUMAN, Q96RU3Function: May act as a link between RND2 signaling and regulation of the actin cytoskeleton (By similarity). Requiredto coordinate membrane tubulation with reorganization of the actin cytoskeleton during the late stage ofclathrin-mediated endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserineand promotes membrane invagination and the formation of tubules. Also enhances actin polymerization via therecruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. Actin polymerization may promote the fissionof membrane tubules to form endocytic vesicles. May be required for the lysosomal retention of FASLG/FASL
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FNBP1 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FNBP1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: FNBP1 (NM_015033) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FNBP1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FNBP1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FNBP1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
FNBP1 for ontologies About GeneDecksing
|
Pathways & Interactions
for FNBP1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for FNBP1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/37 Interacting proteins for FNBP1 (Q96RU31, 2, 3 ENSP000004136254) via UniProtKB, MINT, STRING, and/or I2D (see all 37)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| TNKS | O952711, 2, 3, ENSP000003115794 | EBI-2948562,EBI-1105254 MINT-7027181 MINT-7027206 MINT-7026692 MINT-7027261 MINT-7027245 MINT-7027162 MINT-7027223 I2D:
score=6 STRING: ENSP00000311579 | | SNX2 | O607491, 2, 3, ENSP000003688314 | EBI-2948562,EBI-1046690 MINT-7026677 MINT-7027275 I2D:
score=6 STRING: ENSP00000368831 | | DAAM1 | Q9Y4D12, 3, ENSP000002471704 | MINT-7146160 I2D:
score=1 STRING: ENSP00000247170 | | GABARAP | O951661, 3 | EBI-2948562,EBI-712001 I2D:
score=3 | | FASLG | P480232, 3, ENSP000003566944 | MINT-7137047 MINT-7137280 MINT-7137291 MINT-7137059 I2D:
score=5 STRING: ENSP00000356694 |
About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006897 | endocytosis |
IEA | -- | | GO:0007399 | nervous system development |
-- | -- |
FNBP1 for ontologies About GeneDecksing
|
Drugs & Compounds
for FNBP1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FNBP1
10/125 HMDB Compounds for FNBP1 (see all 125) About this table
Search CenterWatch for drugs/clinical trials and news about FNBP1
|
Transcripts
for FNBP1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FNBP1 gene: NM_015033.2 Unigene Cluster for FNBP1: Formin binding protein 1 Hs.189409 [show with all ESTs]Unigene Representative Sequence: AL04993511 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000372416 ENST00000479142 ENST00000449089(uc004byx.1 uc004byy.1 uc004byz.1)
ENST00000355681 ENST00000478129 ENST00000462766 ENST00000482107 ENST00000491905
ENST00000446176(uc011mbu.1 uc004byw.1 uc011mbv.1 uc011mbw.1)
ENST00000420781(uc004bza.2) ENST00000443566
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FNBP1 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FNBP1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FNBP1 (NM_015033) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FNBP1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FNBP1 |
Additional cDNA sequence: AB011126.1 AF265550.1 AK000975.1 AK001616.1 AK023681.1 AK090963.1 AK293743.1 AL049935.1 AL832949.1 AY952886.3 BC009262.2 BC018159.1 BC062463.1 BC094851.1 BC101755.1 BC143513.1 BC143514.1 BC143515.1 24/27 DOTS entries (see all 27): DT.99963101 DT.75104267 DT.408472 DT.95098992 DT.97845617 DT.419332 DT.97845616 DT.101966743 DT.91997887 DT.310649 DT.100775911 DT.435785 DT.95358258 DT.121170262 DT.100680973 DT.91751661 DT.121170211 DT.121170193 DT.100025033 DT.100775913 DT.87015403 DT.95157239 DT.121170099 DT.91751662 24/424 AceView cDNA sequences (see all 424): BQ918663 BM725380 BG685946 AA626132 AA206843 BX431686 BM455891 AU118047 BM478022 AA705001 BM697621 AA733093 AA449152 AA381979 AI360858 AA465250 BC062463 AA482387 AA864599 BM475826 CR616499 M79001 AA262829 CD172352
GeneLoc Exon Structure
|
Expression
for FNBP1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FNBP1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTCTTATTG
About this image
See FNBP1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FNBP1
SOURCE GeneReport for Unigene cluster: Hs.189409
UniProtKB/Swiss-Prot: FNBP1_HUMAN, Q96RU3Tissue specificity: Very highly expressed in the epithelial cells of the gastrointestinal tract, respiratory,reproductive and urinary systems. Also highly expressed in brown adipose tissue, cardiomyocytes, enteric ganglia andglucagon producing cells of the pancreas. Expressed in germ cells of the testis and all regions of the brain
SABiosciences Custom PCR Arrays for FNBP1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FNBP1
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FNBP1 |
Orthologs
for FNBP1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for FNBP1 gene from 5/20 species (see all 20) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
FNBP11 |
formin binding protein 1 |
83.63(n)
89.3(a) |
|
417187 XM_415469.3 XP_415469.2 |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.105872 |
Xenopus laevis transcribed sequence with weak similarity more |
84.43(n) |
|
BX844235.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC5620491 |
formin-binding protein 1-like |
72.1(n)
76.37(a) |
|
562049 XM_685446.5 XP_690538.5 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Cip46 |
Cip4 |
33(a) |
1 → many |
3L(4322491-4364102) |
worm
(Caenorhabditis elegans) |
Secernentea |
toca-16toca-26 |
TOCA (Transducer Of Cdc42-dependent Actin assembly...TOCA (Transducer Of Cdc42-dependent Actin assembly... |
24(a)22(a) |
many ↔ manymany ↔ many |
X(1511063-1521482) III(13755841-13759350) |
ENSEMBL Gene Tree for FNBP1 (if available)
TreeFam Gene Tree for FNBP1 (if available) |
Paralogs
for FNBP1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FNBP1 gene
- TRIP102 FNBP1L2
3 SIMAP similar genes for FNBP1 using alignment to 7 protein entries: FNBP1_HUMAN (see all proteins):FNBP1L TRIP10 STP
FNBP1 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for FNBP1
PGOHUM00000240689 PGOHUM00000237567
|
Genomic Variants
for FNBP1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FNBP1 (132649466 - 132805473 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for FNBP1
1 CNV: 6719 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FNBP1 |
|
Disorders
/ Diseases
for FNBP1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FNBP1 for disorders About GeneDecksing
OMIM gene information: 606191
OMIM disorders: --
UniProtKB/Swiss-Prot: FNBP1_HUMAN, Q96RU3
Note=A chromosomal aberration involving FNBP1 is found in acute leukemias. Translocation t(9;11)(q34;q23) withMLL. The relatively low incidence of the MLL-FNBP1 fusion protein in acute leukemia may reflect the marginal capacityof this fusion protein to induce cellular transformation
5  diseases for FNBP1: About MalaCardswiskott-aldrich syndrome multiple myeloma myeloma leukemia
neuronitis
1 Novoseek disease relationship for FNBP1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| leukemia |
10.3 |
2 |
11438682 (1) |
Human Genome Epidemiology (HuGE) Navigator: FNBP1 (1 document)
Export disorders for FNBP1 gene to outside databases
|
Publications
for FNBP1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FNBP1 gene, integrated from 9 sources (see all 53):
(articles sorted by number of sources associating them with FNBP1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia. (PubMed id 11438682)1, 2, 3, 9 Fuchs U.... Borkhardt A. (2001)
- Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)1, 2, 3 Nagase T....Ohara O. (1998)
- A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis. (PubMed id 15252009)1, 2, 9 Kamioka Y....Mochizuki N. (2004)
- The formin-binding protein 17, FBP17, binds via a TNKS binding motif to tankyrase, a protein involved in telomere maintenance. (PubMed id 14596906)1, 2, 9 Fuchs U.... Borkhardt A. (2003)
- Coordination between the actin cytoskeleton and membrane deformation by a novel membrane tubulation domain of PCH proteins is involved in endocytosis. (PubMed id 16418535)1, 2, 9 Tsujita K....Takenawa T. (2006)
- Curved EFC/F-BAR-domain dimers are joined end to end into a filament for membrane invagination in endocytosis. (PubMed id 17512409)1, 2, 9 Shimada A....Yokoyama S. (2007)
- Regulation of FasL expression: a SH3 domain containing protein family involved in the lysosomal association of FasL. (PubMed id 16318909)1, 2, 9 Qian J....Janssen O. (2006)
- The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics. (PubMed id 16630611)1, 2 Aspenstroem P.... Johansson A.-S. (2006)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins. (PubMed id 16326391)1, 2 Itoh T....De Camilli P. (2005)
|
External Searches for FNBP1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FNBP1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FNBP1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing FNBP1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for FNBP1 gene:
Search GeneIP for patents involving FNBP1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for FNBP1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for FNBP1 | | OriGene shRNA RFP for FNBP1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FNBP1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FNBP1 | | | OriGene Protein Over-expression Lysate for FNBP1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for FNBP1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FNBP1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FNBP1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for FNBP1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FNBP1 | | OriGene Custom Protein Services for FNBP1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FNBP1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FNBP1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FNBP1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FNBP1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FNBP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FNBP1 |
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| | | | Search Tocris compounds for FNBP1 |
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 | | | FNBP1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FNBP1 |
|  |  |  | | | | ThermoFisher Antibodies for FNBP1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FNBP1 |
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