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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CPNE6 Gene

protein-coding   GIFtS: 55
GCID: GC14P024540

copine VI (neuronal)
 Explore 4 diseases affiliated with
CPNE6 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CPNE6    

Aliases
for CPNE6 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Copine VI (Neuronal)1 2     Neuronal-Copine1
N-COPINE2     N-Copine1
Copine-61     Neuronal-Copine1
Neuronal Copine2     Copine VI3

External Ids:    HGNC: 23191   Entrez Gene: 93622   Ensembl: ENSG000001008847   OMIM: 6056885   UniProtKB: O957413   

Export aliases for CPNE6 gene to outside databases

Previous GC identifers: GC14P021913 GC14P018328 GC14P022530 GC14P023609 GC14P004655


Summaries
for CPNE6 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CPNE6:
This gene encodes a brain-specific member of the copine family, which is composed of calcium-dependent membrane-binding
proteins. The gene product contains two N-terminal C2 domains, and one von Willebrand factor A domain. It may have a
role in synaptic plasticity. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CPNE6_HUMAN, O95741
Function: May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties. May have a
role in synaptic plasticity (By similarity)

Gene Wiki entry for CPNE6


Genomic Views
for CPNE6 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CPNE6 gene promoter:
         COUP-TF1   COUP-TF   COUP   HNF-4alpha2   HNF-4alpha1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CPNE6 promoter sequence
   Search SABiosciences Chromatin IP Primers for CPNE6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CPNE6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q11.2   Ensembl cytogenetic band:  14q11.2   HGNC cytogenetic band: 14q11.2

CPNE6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CPNE6 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P024540:  view genomic region     (about GC identifiers)

Start:
 24,540,046 bp from pter      End:
 24,547,309 bp from pter
Size:
 7,264 bases      Orientation:
 plus strand

Proteins
for CPNE6 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CPNE6_HUMAN, O95741 (See protein sequence)
Recommended Name: Copine-6  
Size: 557 amino acids; 61991 Da
Secondary accessions: B2RAG6 D3DS55 Q53HA6 Q8WVG1

Explore the universe of human proteins at neXtProt for CPNE6: NX_O95741

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O95741

    • CPNE6 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_006023.1  
    ENSEMBL proteins: 
     ENSP00000380211   ENSP00000454192   ENSP00000454093   ENSP00000453483   ENSP00000454075  
     ENSP00000454166   ENSP00000453352   ENSP00000453326   ENSP00000452826   ENSP00000453261  
     ENSP00000452884   ENSP00000454172   ENSP00000452653   ENSP00000440077   ENSP00000216775  

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    Novus Biologicals CPNE6 Protein
    Novus Biologicals CPNE6 Lysate
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CPNE6

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005624membrane fraction ----
    GO:0016020membrane IEA--
    GO:0030424axon IEA--
    GO:0030425dendrite IEA--


    CPNE6 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for CPNE6

    Protein Domains /
    Families
    for CPNE6 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CPNE6 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR018029 C2_membr_targeting
     IPR008973 C2_Ca/lipid-bd_dom_CaLB
     IPR010734 Copine
     IPR000008 C2_Ca-dep
     IPR002035 VWF_A

    Graphical View of Domain Structure for InterPro Entry O95741

    ProtoNet protein and cluster: O95741

    2 Blocks protein families:
    IPB000008 C2 domain
    IPB010734 Copine


    UniProtKB/Swiss-Prot: CPNE6_HUMAN, O95741
    Similarity: Belongs to the copine family
    Similarity: Contains 2 C2 domains
    Similarity: Contains 1 VWFA domain


    Function
    for CPNE6 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CPNE6_HUMAN, O95741
    Function: May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties. May have a
    role in synaptic plasticity (By similarity)

    miRNA
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    hsa-mir-197 (MIRT003821)

    OriGene 3'-UTR Clone: CPNE6
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    SwitchGear 3'UTR luciferase reporter plasmid: CPNE6 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CPNE6 (see all 4)
    OriGene shRNA RFP: CPNE6
    OriGene siRNA: CPNE6
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CPNE6

    Gene Editing
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    Clone
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    Search LifeMap BioReagents cell lines for CPNE6

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001786phosphatidylserine binding IEA--
    GO:0005215transporter activity TAS9645480
    GO:0005509calcium ion binding TAS9645480


    CPNE6 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for CPNE6:
     Increased 8N DNA content 


    Pathways & Interactions
    for CPNE6 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CPNE6

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5/14 Interacting proteins for CPNE6 (O957412, 3 ENSP000002167754) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMN1Q166372, 3MINT-8271003 I2D: score=2 
    SMN2Q166372, 3MINT-8271003 I2D: score=2 
    ANXA7P200732, 3MINT-8248197 I2D: score=2 
    CDKN1AP389362, 3MINT-8251747 I2D: score=2 
    GRB7Q144512, 3MINT-8256646 I2D: score=2 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006629lipid metabolic process TAS9645480
    GO:0007268synaptic transmission TAS9645480
    GO:0007399nervous system development TAS9645480
    GO:0016192vesicle-mediated transport TAS9645480


    CPNE6 for ontologies           About GeneDecksing



    Drugs & Compounds
    for CPNE6 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CPNE6

    10/125 HMDB Compounds for CPNE6 (see all 125)    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    PS(14:0/14:0)Phosphatidylserine(14:0/14:0) (see all 7)----
    PS(14:0/14:1(9Z))Phosphatidylserine(14:0/14:1n5) (see all 13)----
    PS(14:0/16:0)1-myristoyl-2-palmitoyl-sn-glycero-3-phosphoserine (see all 7)----
    PS(14:0/16:1(9Z))PS(14:0/16:1n7) (see all 13)----
    PS(14:0/18:0)Phosphatidylserine(32:0) (see all 7)----
    PS(14:0/18:1(9Z))PSer(14:0/18:1n9) (see all 13)----
    PS(14:0/18:2(9Z,12Z))PS(14:0/18:2) (see all 13)----
    PS(14:0/18:3(9Z,12Z,15Z))Phosphatidylserine(14:0/18:3) (see all 14)----
    PS(14:0/20:3(8Z,11Z,14Z))PSer(14:0/20:3) (see all 14)----
    Search CenterWatch for drugs/clinical trials and news about CPNE6 

    Transcripts
    for CPNE6 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CPNE6 gene: 
    NM_006032.2  

    Unigene Cluster for CPNE6:

    Copine VI (neuronal)
    Hs.6132  [show with all ESTs]
    Unigene Representative Sequence: AL137688
    18/20 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):
    ENST00000397016(uc010tnv.2 uc001wll.3) ENST00000560356 ENST00000558450
    ENST00000558995(uc001wlm.3) ENST00000559778 ENST00000560761 ENST00000557889
    ENST00000558541 ENST00000558859 ENST00000560092 ENST00000559197 ENST00000560828
    ENST00000560884 ENST00000558795 ENST00000559207 ENST00000460657 ENST00000557829(uc001wln.3)
    ENST00000560845

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmid: CPNE6 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CPNE6 (see all 4)
    OriGene shRNA RFP: CPNE6
    OriGene siRNA: CPNE6
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CPNE6
    Clone
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    GenScript: all cDNA clones in your preferred vector: CPNE6 (NM_006032)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CPNE6 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CPNE6
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CPNE6

    Additional cDNA sequence: 

    AB009288.1 AK125195.1 AK222675.1 AK293655.1 AK294460.1 AK314182.1 AL050397.1 AL137688.1 
    BC018046.1 

    13 DOTS entries:

    DT.310911  DT.95172092  DT.95172095  DT.120757432  DT.120757422  DT.120757419  DT.75118801  DT.120757417 
    DT.91659560  DT.100806112  DT.120757414  DT.95172091  DT.95172094 

    24/72 AceView cDNA sequences (see all 72):

    NM_006032 AK125195 AI628393 T08617 AI493694 CR598214 BM925748 BI551073 
    BX450322 T33805 AI381598 BI820229 BX451552 BI552844 BG714305 BI547651 
    CB153180 AW161151 AB009288 BP348888 BX419926 BM545273 BI914650 CB134349 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for CPNE6 (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b · 9c ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18
    SP1:                                                                                                                                                            
    SP2:                                                              -                                                                                             
    SP3:                                                                                                                                                            
    SP4:                    -                                                                                                                                       
    SP5:                                                              -     -     -                                                                                 


    ECgene alternative splicing isoforms for CPNE6

    Expression
    for CPNE6 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CPNE6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CGGCTGCTGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CPNE6 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    EyeInner Nuclear LayerGABAergic Amacrine CellsAmacrine, Retina
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See CPNE6 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CPNE6

    SOURCE GeneReport for Unigene cluster: Hs.6132
        SABiosciences Custom PCR Arrays for CPNE6
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CPNE6

    Orthologs
    for CPNE6 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CPNE6 gene from 3/18 species (see all 18)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    worm
    (Caenorhabditis elegans)    		 Secernentea Y73F8A.193   -- 23(a)   IV(15361756-15368155)   --
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT5G639706
    AT1G793806
    (see all 5)    		 Copine (Calcium-dependent phospholipid-binding pro...
    Ca(2)-dependent phospholipid-binding family protei...
    (see all 5)    		 19(a)
    18(a)
    (see all 5)    		 possible ortholog
    possible ortholog
    (see all 5)    		 5(25606771-25609247)
    1(29860491-29863316)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    (see all 7)    		 copine, putative, expressed
    (see all 7)    		 8(a)
    19(a)
    (see all 7)    		 possible ortholog
    possible ortholog
    (see all 7)    		 9(22507403-22512808)
    1(42349883-42354354)


    ENSEMBL Gene Tree for CPNE6 (if available)
    TreeFam Gene Tree for CPNE6 (if available) 

    Paralogs
    for CPNE6 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CPNE6 gene
    CPNE92  CPNE22  CPNE32  CPNE52  CPNE82  CPNE42  CPNE72  CPNE12  
    9 SIMAP similar genes for CPNE6 using alignment to 15 protein entries:     CPNE6_HUMAN (see all proteins):
    CPNE4    CPNE7    CPNE2    CPNE8    CPNE9    CPNE3
    CPNE1    CPNE5    DKFZp666C234

    CPNE6 for paralogs           About GeneDecksing



    Genomic Variants
    for CPNE6 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/26 NCBI SNPs in CPNE6 are shown (see all 26)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 14 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs736030541,2
    		C,--4653836(+) GGACTG/CTCTCC 1 -- us2k11Minor allele frequency- C:0.50WA 2
    rs756574981,2
    		--4653989(+) AGGGAT/CAGACT 1 -- us2k11Minor allele frequency- C:0.01EA 120
    rs2014671511,2
    		C--4654061(+) GTCCCA/CAAGCC 1 -- us2k10--------
    rs736030561,2
    		C,F,--4654181(+) AGCCCC/TAGTGT 1 -- us2k13Minor allele frequency- T:0.05WA 122
    rs1120127021,2
    		--4654354(+) TCAGCA/GACTAA 1 -- us2k12Minor allele frequency- G:0.04CSA WA 120
    rs116207201,2
    		C,F,H--4662549(+) AGGAGC/ATGAAC 1 -- ds50018Minor allele frequency- A:0.01NS NA 1060
    rs1502010551,2
    		--24538937(+) AATCAA/TCGCCT 1 -- ut310--------
    rs1386302901,2
    		--24538939(+) TCATCA/GCCTGC 1 -- spd10--------
    rs1445215001,2
    		--24539025(+) ACAGTA/GGAGAA 1 -- int10--------
    rs612085381,2
    		C,--24539083(+) AGGAG-/AAAAAA 1 -- int10--------

    HapMap Linkage Disequilibrium report for CPNE6 (24540046 - 24547309 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for CPNE6
         1 CNV: 49327

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    Disorders / Diseases
    for CPNE6 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CPNE6 for disorders           About GeneDecksing

    OMIM gene information: 605688    OMIM disorders: --

    4 diseases for CPNE6:    About MalaCards
    neuronitis    hermaphroditism    infertility    osteosarcoma

    Human Genome Epidemiology (HuGE) Navigator: CPNE6 (2 documents)

    Export disorders for CPNE6 gene to outside databases

    Publications
    for CPNE6 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CPNE6 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with CPNE6)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. N-copine: a novel two C2-domain-containing protein with neuronal activity-regulated expression. (PubMed id 9645480)1, 2, 3 Nakayama T.... Kuwajima G. (1998)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    5. Investigation of genetic susceptibility factors for h uman longevity - A targeted nonsynonymous SNP study. (PubMed id 20800603)1 Flachsbart F....Nebel A. (2010)
    6. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    8. Characterization of human copine III as a phosphoprotein with associated kinase activity. (PubMed id 11041869)1 Caudell E.G....Grimm E.A. (2000)
    9. Ca2(+)-dependent interaction of N-copine, a member of the two C2 domain protein family, with OS-9, the product of a gene frequently amplified in osteosarcoma. (PubMed id 10403379)1 Nakayama T....Sakata T. (1999)
    10. Localization and subcellular distribution of N-copine in mouse brain. (PubMed id 9886090)1 Nakayama T....Kuwajima G. (1999)

    External Searches for CPNE6 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing CPNE6 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9362 HGNC: 2319 AceView: CPNE6 Ensembl:ENSG00000100884 euGenes: HUgn9362
    ECgene: CPNE6 H-InvDB: CPNE6

    Other Databases showing CPNE6 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CPNE6 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CPNE6 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CPNE6 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CPNE6 gene:
    Search GeneIP for patents involving CPNE6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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