Aliases for CPNE6 Gene
External Ids for CPNE6 Gene
Previous GeneCards Identifiers for CPNE6 Gene
This gene encodes a member of the copine family. Members of this family are calcium-dependent, phospholipid-binding proteins with C2 domains, two calcium- and phospholipid-binding domains. Through their domain structure and lipid binding capabilities, these proteins may play a role in membrane trafficking. This protein is thought to be brain-specific and has a domain structure of two N-terminal C2 domains and one von Willebrand factor A domain. It may have a role in synaptic plasticity. [provided by RefSeq, Jul 2013]
GeneCards Summary for CPNE6 Gene
CPNE6 (Copine 6) is a Protein Coding gene. Diseases associated with CPNE6 include Presbyopia and Eye Accommodation Disease. Among its related pathways are Metabolism and Glycerophospholipid biosynthesis. GO annotations related to this gene include calcium ion binding and phosphatidylserine binding. An important paralog of this gene is CPNE7.
UniProtKB/Swiss-Prot for CPNE6 Gene
Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Binds phospholipid membranes in a calcium-dependent manner (By similarity). Plays a role in dendrite formation by melanocytes (PubMed:23999003).