External Ids for CINP Gene
The protein encoded by this gene is reported to be a component of the DNA replication complex as well as a genome-maintenance protein. It may interact with proteins important for replication initiation and has been shown to bind chromatin at the G1 phase of the cell cycle and dissociate from chromatin with replication initiation. It may also serve to regulate checkpoint signaling as part of the DNA damage response. [provided by RefSeq, Jul 2013]
GeneCards Summary for CINP Gene
CINP (Cyclin-Dependent Kinase 2 Interacting Protein) is a Protein Coding gene. Diseases associated with CINP include dysthymic disorder.
UniProtKB/Swiss-Prot for CINP Gene
Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling.