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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AVPR1B Gene

protein-coding   GIFtS: 67
GCID: GC01P206223

arginine vasopressin receptor 1B


(Previous symbol: AVPR3)
 Explore 21 diseases affiliated with
AVPR1B via our new
 Human Malady Compendium 
Biological research products
for AVPR1B
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Arginine Vasopressin Receptor 1B1 2     AVPR V32 3
AVPR31 2 3 5     Arginine Vasopressin Receptor 32
Antidiuretic Hormone Receptor 1b2 3     Pituitary Vasopressin Receptor 32
Vasopressin V3 Receptor2 3     Vasopressin V1b Receptor2
V1bR2 3     VPR33
AVPR V1b2 3     

External Ids:    HGNC: 8961   Entrez Gene: 5532   Ensembl: ENSG000001980497   OMIM: 6002645   UniProtKB: P479013   

Export aliases for AVPR1B gene to outside databases

Previous GC identifers: GC01U990014 GC01P202767 GC01P204390 GC01P177157


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for AVPR1B:
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of
G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which
stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior
pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as
well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene
has been reported but its function is not known. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: V1BR_HUMAN, P47901
Function: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a
phosphatidyl-inositol-calcium second messenger system

summary for AVPR1B:
Vasopressin receptors are a group of G-protein-coupled receptors that mediate vasoconstriction, antidiuresis
and ACTH release. They are currently divided into three subtypes, V1A, V1B and V2 and are closely related to
oxytocin receptors (OT). V1A is coupled to Gq/11 proteins and is found at high density on smooth muscle
cells. It is involved in regulation of blood pressure through arterial vasoconstriction and has been found
to stimulate VEGF secretion. V1B is located in the hypothalamus, where it controls ACTH secretion, and in
the pancreas, where it is involved in insulin release. V2 is coupled to Gs proteins and is found exclusively
on the basolateral membrane of collecting duct cells in the kidney, where it regulates water excretion.

Gene Wiki entry for AVPR1B (Arginine vasopressin receptor 1B)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_086602.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AVPR1B gene promoter:
         HFH-3   GR   AML1a   GR-beta   FOXD3   LCR-F1   HEN1   FOXI1   GR-alpha   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAVPR1B promoter sequence
   Search SABiosciences Chromatin IP Primers for AVPR1B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AVPR1B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32   Ensembl cytogenetic band:  1q32.1   HGNC cytogenetic band: 1q32

AVPR1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AVPR1B gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P206223:  view genomic region     (about GC identifiers)

Start:
206,223,976 bp from pter      End:
206,231,639 bp from pter
Size:
7,664 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: V1BR_HUMAN, P47901 (See protein sequence)
Recommended Name: Vasopressin V1b receptor  
Size: 424 amino acids; 46971 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Secondary accessions: B0M0J6 Q5TZ00

Explore the universe of human proteins at neXtProt for AVPR1B: NX_P47901

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P47901

  • AVPR1B Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_000698.1  
    ENSEMBL proteins: 
     ENSP00000356094  
    Reactome Protein details: P47901
    Human Recombinant Protein Products: 
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    Uscn Proteins for AVPR1B

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005768endosome TAS10858434
    GO:0005886plasma membrane TAS--
    GO:0005887integral to plasma membrane TAS7805841
    GO:0016021integral to membrane ----


    AVPR1B for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for AVPR1B


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    AVPR1B for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR000628 Vprs_rcpt_V1B
     IPR000276 GPCR_Rhodpsn
     IPR001817 Vasoprsn_rcpt

    Graphical View of Domain Structure for InterPro Entry P47901

    ProtoNet protein and cluster: P47901

    2 Blocks protein families:
    IPB000628 Vasopressin VIB receptor signature
    IPB001817 Vasopressin receptor signature


    UniProtKB/Swiss-Prot: V1BR_HUMAN, P47901
    Similarity: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: V1BR_HUMAN, P47901
    Function: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a
    phosphatidyl-inositol-calcium second messenger system

         Genatlas biochemistry entry for AVPR1B:
    vasopressin pituitary V3-type,receptor,G protein coupled receptor superfamily

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    hsa-miR-3176 hsa-miR-3922-3p
    SwitchGear 3'UTR luciferase reporter plasmidAVPR1B 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005000vasopressin receptor activity IEA--
    GO:0005080protein kinase C binding TAS10858434
    GO:0017046peptide hormone binding ----
    GO:0042803protein homodimerization activity ----


    AVPR1B for ontologies           About GeneDecksing


    6 GenomeRNAi human phenotypes for AVPR1B:
     Decreased Hepatitis C virus re  Decreased Salmonella enterica   Decreased Salmonella enterica   Decreased substrate adherent c 
     Decreased telomerase activity  Increased gamma-H2AX phosphory 

    Animal Models:
         Mouse knock-outs for AVPR1B: Avpr1btm1Wsy Avpr1btm1Gzt
         4 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Avpr1b):
     behavior/neurological  endocrine/exocrine gland  homeostasis/metabolism  nervous system 

    AVPR1B for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/7 super-pathways (see all 7About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Class A/1 (Rhodopsin-like receptors)
    Class A/1 (Rhodopsin-like receptors)1.00
    GPCRs, Class A Rhodopsin-like0.41
    GPCR ligand binding0.75
    Neuroactive ligand-receptor interaction0.38
    Peptide ligand-binding receptors0.61
    2Signaling by GPCR
    Signaling by GPCR1.00
    Signal Transduction0.56
    GPCR downstream signaling0.89
    3G alpha (q) signalling events
    G alpha (q) signalling events1.00
    Gastrin-CREB signalling pathway via PKC and MAPK0.90
    4Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q
    Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q1.00
    Peptide GPCRs0.46
    5Vasopressin-like receptors
    Vasopressin-like receptors1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for AVPR1B
        Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q


    2 BioSystems Pathways for AVPR1B 
        GPCRs, Class A Rhodopsin-like
    Peptide GPCRs

    5/9        Reactome Pathways for AVPR1B (see all 9)
        GPCR downstream signaling
    Peptide ligand-binding receptors
    Gastrin-CREB signalling pathway via PKC and MAPK
    Signaling by GPCR
    Vasopressin-like receptors


    3         Kegg Pathways  (Kegg details for AVPR1B):
        Calcium signaling pathway
    Neuroactive ligand-receptor interaction
    Vascular smooth muscle contraction


    AVPR1B for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AVPR1B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/129 Interacting proteins for AVPR1B (P479013 ENSP000003560944) via UniProtKB, MINT, STRING, and/or I2D (see all 129)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AVPP011853, ENSP000003696474I2D: score=1 STRING: ENSP00000369647
    GRK5P349473, ENSP000003766094I2D: score=2 STRING: ENSP00000376609
    PRKCAP172523, ENSP000002843844I2D: score=1 STRING: ENSP00000284384
    ADRA1DENSP000003687664STRING: ENSP00000368766
    AGTR1ENSP000002734304STRING: ENSP00000273430
    About this table

    Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001992regulation of systemic arterial blood pressure by vasopressin IEA--
    GO:0006950response to stress ----
    GO:0007186G-protein coupled receptor signaling pathway TAS10858434
    GO:0007188adenylate cyclase-modulating G-protein coupled receptor signaling pathway ----
    GO:0007202activation of phospholipase C activity TAS7805841


    AVPR1B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    AVPR1B for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for AVPR1B available from Tocris Bioscience    About this table
    CompoundAction CAS #
    d[Leu4,Lys8]-VP Selective V1B agonist[42061-33-6]
    [Arg8]-VasopressinAntidiuretic hormone[113-79-1]
    OPC 2128Orally active vasopressin V1 antagonist[131631-89-5]
    DesmopressinSynthetic vasopressin analog; V1B and V2 agonist[16679-58-6]
    d[Cha4]-AVPPotent and selective human V1B agonist[500170-27-4]

    2 HMDB Compounds for AVPR1B    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    Vasopressin3-(Phenylalanine)-8-lysine oxytocin (see all 8)11000-17-2--

    3 DrugBank Compounds for AVPR1B    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    TerlipressinN-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin (see all 4)14636-12-5target--17027167 17284170 16720725 16114100 15993108
    Vasopressin3-Isoleucyl vasopressin (see all 8)11000-17-2target--17284170 16720725 16114100 17027167 15993108
    Desmopressin1-Desamino-8-D-arginine vasopressin (see all 4)16679-58-6target--18655906 15613460 14971638

    4 Novoseek chemical compound relationships for AVPR1B gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    acth 74.5 11 15642780 (2), 15512850 (1), 7626108 (1), 12213135 (1) (see all 10)
    desmopressin 69.7 7 18426818 (2), 9264324 (1), 11380491 (1)
    arginine 59.5 10 15094789 (1), 17909131 (1), 7626108 (1), 18384079 (1) (see all 8)
    corticosterone 15.5 1 12213135 (1)

    Search CenterWatch for drugs/clinical trials and news about AVPR1B / V1BR 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for AVPR1B gene: 
    NM_000707.3  

    Unigene Cluster for AVPR1B:

    Arginine vasopressin receptor 1B
    Hs.1372  [show with all ESTs]
    Unigene Representative Sequence: L37112
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000367126(uc001hds.2)

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    Additional cDNA sequence: 

    AF030512.1 AF101726.1 D31833.1 EU432111.1 L37112.1 

    2 DOTS entries:

    DT.206498  DT.100725325 

    5 AceView cDNA sequences:

    AF101726 AF030512 L37112 NM_000707 D31833 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AVPR1B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTGTCCCAGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See AVPR1B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AVPR1B

    SOURCE GeneReport for Unigene cluster: Hs.1372
        SABiosciences Expression via Pathway-Focused PCR Arrays including AVPR1B: 
              Neurotransmitter Receptors in human mouse rat
              G Protein Coupled Receptors 384HT in human mouse rat
              Hypertension in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AVPR1B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for AVPR1B gene from 2/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves AVPR1B1 arginine vasopressin receptor 1B 68.95(n)
    62.99(a)
      428263  NM_001031498.1  NP_001026669.1 
    worm
    (Caenorhabditis elegans)
    Secernentea T07D10.26
    F14F4.16
    Protein F14F4.1
    22(a)
    19(a)
    many ↔ many
    many ↔ many
    I(12621161-12623074)
    X(14924963-14928864)


    ENSEMBL Gene Tree for AVPR1B (if available)
    TreeFam Gene Tree for AVPR1B (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for AVPR1B gene
    GPR1502  AVPR1A2  AVPR22  OXTR2  GNRHR2  NPSR12  GNRHR22  
    4 SIMAP similar genes for AVPR1B using alignment to 1 protein entry:     V1BR_HUMAN:
    AVPR1    AVPR1A    OXTR    AVPR2

    AVPR1B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/229 NCBI SNPs in AVPR1B are shown (see all 229    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1840743481,2
    --206222354(+) CCCAGA/CTACTT 1 -- us2k10--------
    rs1890499321,2
    --206222425(+) TTGTGC/TCACTG 1 -- us2k10--------
    rs284476451,2
    C,F--206222490(+) AAAAAG/AGCAAG 1 -- us2k1 trp32Minor allele frequency- A:0.50NA WA 4
    rs2019123841,2
    C--206222503(-) GAAGTC/GCTTTT 1 -- us2k10--------
    rs1917110621,2
    --206222540(+) TGAGAG/TTCTGG 1 -- us2k10--------
    rs353946841,2
    C,F,--206222677(+) CAAGCC/TCTGCC 1 -- us2k14Minor allele frequency- T:0.38NS WA CSA 85
    rs346455951,2
    C,--206222705(+) TCTCCT/CGCCTC 1 -- us2k12Minor allele frequency- C:0.01NS 84
    rs347869641,2
    C,F,--206222742(-) GTGGCG/AGGCGC 1 -- us2k14Minor allele frequency- A:0.21NS NA 90
    rs346026591,2
    C,F,H,--206223168(+) TTACTC/TGTTCA 1 -- us2k113Minor allele frequency- T:0.05NS NA WA 1452
    rs1880429481,2
    --206223206(+) TTCTCG/TGGGCC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for AVPR1B (206223976 - 206231639 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for AVPR1B
         1 CNV: 4268
    Human Gene Mutation Database (HGMD): AVPR1B

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    AVPR1B for disorders           About GeneDecksing

    OMIM gene information: 600264    OMIM disorders: --

    20/21 diseases for AVPR1B (see all 21):    About MalaCards
    acth-secreting pituitary adenoma    pituitary adenoma    adenoma    attention deficit hyperactivity disorder
    nephrogenic diabetes insipidus    diabetes insipidus    melancholia    cushing's syndrome
    adrenal hyperplasia    panic disorder    mood disorder    small cell carcinoma
    carcinoid tumors    neuroendocrine tumor    was-related disorders    pituitary tumor
    rabies    choroiditis    breast cancer    carcinoma

    1 disease from the University of Copenhagen DISEASES database for AVPR1B:
    Major depressive disorder

    5 Novoseek disease relationships for AVPR1B gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cushing syndrome 66.5 1 9838245 (1)
    carcinoid 51.1 1 9425403 (1)
    major depression 30 2 15094789 (2)
    adenoma 28.6 1 9425403 (1)
    tumors 0 4 9167961 (1), 18426818 (1), 11932296 (1)

    Genetic Association Database (GAD): AVPR1B
    Human Genome Epidemiology (HuGE) Navigator: AVPR1B (13 documents)

    Export disorders for AVPR1B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AVPR1B gene, integrated from 9 sources (see all 76):
    (articles sorted by number of sources associating them with AVPR1B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and functional expression of a cDNA encoding the human V1b vasopressin receptor. (PubMed id 7929452)1, 2, 3, 9 Sugimoto T....Kawashima H. (1994)
    2. Evidence of an association between the vasopressin V1b receptor gene (AVPR1B) and childhood-onset mood disorders. (PubMed id 17909131)1, 2, 9 Dempster E.L.... Barr C.L. (2007)
    3. A major SNP haplotype of the arginine vasopressin 1B receptor protects against recurrent major depression. (PubMed id 15094789)1, 4, 9 van West D....Claes S. (2004)
    4. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    5. Nucleotide sequence and structural organization of the human vasopressin pituitary receptor (V3) gene. (PubMed id 10607899)1, 2 Rene P.... de Keyzer Y. (2000)
    6. Expression of all known vasopressin receptor subtypes by small cell tumors implies a multifaceted role for this neuropeptide. (PubMed id 9581826)1, 2 North W.G.... Du J. (1998)
    7. Functional vasopressin V1 type receptors are present in variant as well as classical forms of small-cell carcinoma. (PubMed id 9357056)1, 2 North W.G.... Du J. (1997)
    8. Chromosomal localization of the human V3 pituitary vasopressin receptor gene (AVPR3) to 1q32. (PubMed id 8586456)1, 3 Rousseau-Merck M.F....de Keyzer Y. (1995)
    9. Cloning and characterization of the human V3 pituitary vasopressin receptor. (PubMed id 7805841)1, 2 de Keyzer Y.... Clauser E. (1994)
    10. Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder. (PubMed id 18384079)1, 9 Keck M.E....Binder E.B. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 553 HGNC: 896 AceView: AVPR1B Ensembl:ENSG00000198049 euGenes: HUgn553
    ECgene: AVPR1B Kegg: 553 H-InvDB: AVPR1B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AVPR1B Pharmacogenomics, SNPs, Pathways
    SeattleSNPshttp://pga.gs.washington.edu/data/avpr1b/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AVPR1B gene:
    Search GeneIP for patents involving AVPR1B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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