AGK Gene
protein-coding GIFtS: 54
GCID: GC07P141250
|
|
acylglycerol kinase(Previous name: multiple substrate lipid kinase )
(Previous symbol: MULK)
| |
Aliases
for AGK gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Acylglycerol Kinase1 2 | | MTDPS102 | | MULK1 2 3 5 | | Acylglycerol Kinase, Mitochondrial2 | | Multiple Substrate Lipid Kinase1 2 3 | | HsMuLK3 | | Multi-Substrate Lipid Kinase2 3 | | EC 2.7.1.1073 | | HAGK1 | | EC 2.7.1.943 | | FLJ108421 | | HsMuLK3 | | CATC52 | | MuLK3 |
Export aliases for AGK gene to outside databasesPrevious GC identifers: GC07P140899 GC07P135547 |
Summaries
for AGK gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for AGK:
The protein encoded by this gene is a mitochondrial membrane protein involved in lipid and glycerolipid metabolism. Theencoded protein is a lipid kinase that catalyzes the formation of phosphatidic and lysophosphatidic acids. Defects inthis gene have been associated with mitochondrial DNA depletion syndrome 10. (provided by RefSeq, Feb 2012)
UniProtKB/Swiss-Prot: AGK_HUMAN, Q53H12Function: Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid(LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases theformation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signalingpathway, leading to increased cell growth
Gene Wiki entry for AGK
|
Genomic Views
for AGK gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007914.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the AGK gene promoter:
oct-B3 GATA-3 Pbx1a AML1a Lmo2 HNF-3beta GATA-2 GATA-1 Evi-1 AREB6
Other transcription factors
Search SABiosciences Chromatin IP Primers for AGK
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AGK |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q34 Ensembl cytogenetic band: 7q34 HGNC cytogenetic band: 7q34AGK Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P141250: view genomic region
(about GC identifiers)
Start:
|
141,250,989 bp from pter |
End:
|
141,355,044 bp from pter |
Size:
|
104,056 bases |
Orientation:
|
plus strand |
2 alternative locations:
| Chr7+,CRA_TCAG 140,588,796-140,691,918 | Chr7+,PATCHES 141,330,680-141,351,205 |
|
Proteins
for AGK gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: AGK_HUMAN, Q53H12 (See
protein sequence)Recommended Name: Acylglycerol kinase, mitochondrial precursor Size: 422 amino acids; 47137 Da
Cofactor: Magnesium
Subcellular location: Mitochondrion membrane
Miscellaneous: Overexpressed in prostate cancer, suggesting that it may play a role in initiation and progression ofprostate cancer, processes in which LPA plays key roles
Secondary accessions: Q75KN1 Q96GC3 Q9NP48Alternative splicing: 2 isoforms: Q53H12-1 Q53H12-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for AGK: NX_Q53H12
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q53H12
AGK Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060708.1
ENSEMBL proteins: ENSP00000347581 ENSP00000420776 ENSP00000420540 ENSP00000418789 ENSP00000418101 ENSP00000444349
Human Recombinant Protein Products for AGK:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
AGK for ontologies About GeneDecksing
AGK Antibody Products:
Assay Products for AGK: |
Protein
Domains /
Families
for AGK gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
AGK for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q53H12ProtoNet protein and cluster: Q53H12 UniProtKB/Swiss-Prot: AGK_HUMAN, Q53H12Similarity: Contains 1 DAGKc domain |
Function
for AGK gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: AGK_HUMAN, Q53H12Function: Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid(LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases theformation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signalingpathway, leading to increased cell growthCatalytic activity: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphateCatalytic activity: ATP + 1,2-diacylglycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate Enzyme Numbers (IUBMB): EC 2.7.1.1071 EC 2.7.1.941
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
AGK for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AGK (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AGK (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: AGK (NM_017567) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for AGK | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AGK |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AGK |
|
Pathways & Interactions
for AGK gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Glycerolipid metabolism | | | 2 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Kegg Pathways (Kegg details for AGK):
UniProtKB/Swiss-Prot: AGK_HUMAN, Q53H12Pathway: Lipid metabolism; glycerolipid metabolism
AGK for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AGK
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/264 Interacting proteins for AGK (Q53H122, 3 ENSP000003475814) via UniProtKB, MINT, STRING, and/or I2D (see all 264)
About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway |
IEA | -- | | GO:0046486 | glycerolipid metabolic process |
IEA | -- | | GO:0046513 | ceramide biosynthetic process |
IEA | -- | | GO:0046834 | lipid phosphorylation |
-- | -- |
AGK for ontologies About GeneDecksing
|
Drugs & Compounds
for AGK gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
AGK for compounds About GeneDecksing
 Browse Tocris compounds for AGK
10/928 HMDB Compounds for AGK (see all 928) About this table
10/38 Novoseek chemical compound relationships for AGK gene (see all 38) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| phosphoinositide |
86.2 |
47 |
9854311 (1), 11092809 (1), 15044087 (1), 18043260 (1) (see all 44) |
| phosphatidylinositol |
85.1 |
70 |
7612667 (5), 8999962 (2), 8987988 (2), 9748276 (2) (see all 47) |
| lipid |
84.1 |
468 |
7612667 (5), 20035616 (5), 11736661 (4), 8380145 (3) (see all 99) |
| wortmannin |
76.7 |
15 |
9182708 (3), 9139718 (1), 8943387 (1), 9334339 (1) (see all 12) |
| ptdins(3)p |
75.9 |
1 |
18537792 (1) |
| phosphatidylinositol-3,4,5-trisphosphate |
75.8 |
6 |
15242973 (1), 15505410 (1), 19689267 (1), 12734372 (1) (see all 6) |
| ly294002 |
70.1 |
10 |
9139718 (1), 17302559 (1), 8943387 (1), 15155829 (1) (see all 8) |
| phosphatidylinositol 3-phosphate |
68.9 |
3 |
2168961 (1), 19841139 (1) |
| pip2 |
62.8 |
5 |
15888659 (1), 19689267 (1), 9074761 (1), 11706993 (1) |
| sphingosine |
62.5 |
13 |
15252046 (2), 18638570 (1), 9726979 (1), 17482291 (1) (see all 9) |
Search CenterWatch for drugs/clinical trials and news about AGK
|
Transcripts
for AGK gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for AGK gene: NM_018238.3 Unigene Cluster for AGK: Acylglycerol kinase Hs.743318 [show with all ESTs]Unigene Representative Sequence: NM_01823811 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000355413(uc011krg.1 uc003vwi.2) ENST00000473247 ENST00000495028
ENST00000473884 ENST00000492693(uc003vwh.2) ENST00000494688 ENST00000465241
ENST00000496784 ENST00000496273 ENST00000494053 ENST00000535825
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AGK (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AGK (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: AGK (NM_017567) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for AGK | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AGK |
Additional cDNA sequence: AJ278150.1 AK001704.1 AK222769.1 AK299131.1 AK304502.1 BC009775.1 BC022777.1 10 DOTS entries: DT.305637 DT.454358 DT.95080262 DT.97841242 DT.100816647 DT.95096488 DT.121048299 DT.121048356 DT.95101623 DT.97815872 24/155 AceView cDNA sequences (see all 155): BM505176 BM509576 BM461550 BX382024 CR625177 AK001704 AA694449 CR603206 AA595754 BM697149 AJ278150 AA446901 BI824671 BM544317 BP365260 BU182711 BM917277 BC022777 AA426332 AU133125 BQ440189 NM_018238 AI686706 BM091405
GeneLoc Exon Structure
|
Expression
for AGK gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| AGK expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See AGK Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for AGK
SOURCE GeneReport for Unigene cluster: Hs.743318
UniProtKB/Swiss-Prot: AGK_HUMAN, Q53H12Tissue specificity: Highly expressed in muscle, heart, kidney and brain
SABiosciences Custom PCR Arrays for AGK
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AGK
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat AGK | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AGK | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AGK | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AGK |
Orthologs
for AGK gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for AGK gene from 8/26 species (see all 26) About this table
ENSEMBL Gene Tree for AGK (if available)
TreeFam Gene Tree for AGK (if available) |
Paralogs
for AGK gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for AGK gene
- CERKL2 SPHK12 CERK2 SPHK22
1 SIMAP similar gene for AGK using alignment to 4 protein entries: AGK_HUMAN (see all proteins):FLJ10842
AGK for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for AGK
PGOHUM00000241549 PGOHUM00000233964
|
Genomic Variants
for AGK gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for AGK (141250989 - 141355044 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for AGK
2 CNVs: 47923 82201
1 Indel: 94897
Human Gene Mutation Database (HGMD): AGK
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AGK |
|
Disorders
/ Diseases
for AGK gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
AGK for disorders About GeneDecksing
OMIM gene information: 610345
OMIM disorders: --
UniProtKB/Swiss-Prot: AGK_HUMAN, Q53H12
Defects in AGK are the cause of mitochondrial DNA depletion syndrome type 10 (MTDPS10) [MIM:212350]. Anautosomal recessive mitochondrial disorder characterized by congenital cataracts, hypertrophic cardiomyopathy,skeletal myopathy, exercise intolerance, and lactic acidosis. Mental development is normal, but affected individualsmay die early from cardiomyopathy Defects in AGK are the cause of cataract, congenital, autosomal recessive type 5 (CATC5) [MIM:614691]. CATC5consists of an opacification of the crystalline lens of the eye becoming evident at birth. It frequently results invisual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may bestatic or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visualfunction
20/25  diseases for AGK (see all 25): About MalaCardsmitochondrial dna depletion syndrome amyotrophic lateral sclerosis insulin resistance lateral sclerosis
burkitt's lymphoma pheochromocytoma multiple myeloma osteosarcoma
gout prostate cancer fibrosarcoma myeloma
hepatocellular carcinoma nasopharyngitis retinoblastoma breast carcinoma
colorectal cancer prostatitis breast cancer obesity
9 Novoseek disease relationships for AGK gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| cancer |
32.2 |
16 |
19549252 (2), 19025891 (1), 19368348 (1), 11574762 (1) (see all 10) |
| erythroleukemia |
21.8 |
1 |
7606713 (1) |
| tumors |
6.37 |
10 |
19025891 (1), 19395305 (1), 14729945 (1), 16556064 (1) (see all 7) |
| inflammation |
1.99 |
4 |
19112101 (1), 19641220 (1), 17355200 (1) |
| pheochromocytoma |
0.784 |
2 |
8168074 (1), 7572346 (1) |
| insulin resistance |
0 |
1 |
10768093 (1) |
| autoimmune diseases |
0 |
1 |
17614878 (1) |
| osteosarcoma |
0 |
2 |
8168074 (1), 7572346 (1) |
| prostate cancer |
0 |
16 |
19549252 (4), 16246119 (3), 15939762 (3) |
Human Genome Epidemiology (HuGE) Navigator: AGK (1 document)
Export disorders for AGK gene to outside databases
|
Publications
for AGK gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for AGK gene, integrated from 9 sources (see all 303):
(articles sorted by number of sources associating them with AGK) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel acylglycerol kinase that produces lysophosphatidic acid modulates cross talk with EGFR in prostate cancer cells. (PubMed id 15939762)1, 2, 3, 9 Bektas M.... Spiegel S. (2005)
- MuLK, a eukaryotic multi-substrate lipid kinase. (PubMed id 15252046)1, 3, 9 Waggoner D.W....Bajjalieh S.M. (2004)
- Identification of a truncation mutation of acylglycero l kinase (AGK) gene in a novel autosomal recessive cataract locus. (PubMed id 22415731)1, 2 Aldahmesh M.A....Alkuraya F.S. (2012)
- Molecular diagnosis of infantile mitochondrial disease with targeted next-generation sequencing. (PubMed id 22277967)1, 2 Calvo S.E.... Mootha V.K. (2012)
- Lack of the mitochondrial protein acylglycerol kinase causes Sengers syndrome. (PubMed id 22284826)1, 2 Mayr J.A.... Prokisch H. (2012)
- Functions of the multifaceted family of sphingosine k inases and some close relatives. (PubMed id 17135245)1, 3 Spiegel S. and Milstien S. (2007)
- Further characterization of mammalian ceramide kinase: substrate delivery and (stereo)specificity, tissue distribution, and subcellular localization studies. (PubMed id 16269826)1, 2 Van Overloop H.... Van Veldhoven P.P. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
|
External Searches for AGK gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing AGK gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing AGK gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing AGK gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for AGK | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for AGK gene:
Search GeneIP for patents involving AGK
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for AGK gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | OriGene Antibodies for AGK | | OriGene shRNA RFP for AGK | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AGK | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AGK | | | OriGene Protein Over-expression Lysate for AGK | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for AGK | | OriGene 3'-UTR Clone for AGK | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AGK | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AGK | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for AGK | | OriGene Custom Protein Services for AGK | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat AGK | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AGK | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AGK | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AGK | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AGK | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AGK |
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| | | | Search Tocris compounds for AGK |
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 | | | AGK Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AGK |
|  |  |  |  | | | | ThermoFisher Antibody for AGK |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AGK |
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