ACOT2 Gene
protein-coding GIFtS: 56
GCID: GC14P074036
|
|
acyl-CoA thioesterase 2
| |
Aliases
for ACOT2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Acyl-CoA Thioesterase 21 2 3 | | Mte11 | | ZAP1281 2 3 | | CTE-IA2 | | PTE22 3 5 | | CTE1A2 | | Acyl-Coenzyme A Thioester Hydrolase 2a2 3 | | Acyl-Coenzyme A Thioesterase 2, Mitochondrial2 | | Long-Chain Acyl-CoA Thioesterase 22 3 | | Mitochondrial Acyl-CoA Thioesterase 12 | | PTE2A2 3 | | Peroxisomal Long-Chain Acyl-CoA Thioesterase 22 | | EC 3.1.2.23 8 | | CTE-Ia3 | | MTE12 5 | | |
Export aliases for ACOT2 gene to outside databasesPrevious GC identifers: GC14P073106 GC14P054203 |
Summaries
for ACOT2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ACOT2:
This gene encodes a member of the acyl-CoA thioesterase protein family, and is one of four acyl-CoA hydrolase geneslocated in a cluster on chromosome 14. Alternative splicing results in multiple transcript variants. (provided byRefSeq, Jan 2012)
UniProtKB/Swiss-Prot: ACOT2_HUMAN, P49753Function: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fattyacid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acidsand CoASH. Displays high levels of activity on medium- and long chain acyl CoAs
Gene Wiki entry for ACOT2
|
Genomic Views
for ACOT2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ACOT2 gene promoter:
GR STAT5B AML1a Pax-5 FOXD1 Arnt AREB6 HFH-1 GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for ACOT2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ACOT2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q24.3 Ensembl cytogenetic band: 14q24.3 HGNC cytogenetic band: 14q24.3ACOT2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14P074036: view genomic region
(about GC identifiers)
Start:
|
74,034,324 bp from pter |
End:
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74,042,359 bp from pter |
Size:
|
8,036 bases |
Orientation:
|
plus strand |
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Proteins
for ACOT2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ACOT2_HUMAN, P49753 (See
protein sequence)Recommended Name: Acyl-coenzyme A thioesterase 2, mitochondrial precursor Size: 483 amino acids; 53218 Da
Subcellular location: Mitochondrion
Caution: Was originally (PubMed:10944470) thought to be peroxisomal but was later shown (PubMed:16940157) to bemitochondrial
Sequence caution: Sequence=AAC42007.1; Type=Frameshift; Positions=215, 226;
1 PDB 3D structure from  and Proteopedia  for ACOT2:3HLK (3D)
Secondary accessions: Q3I5F8 Q53EK4 Q9NUX4Alternative splicing: 2 isoforms: P49753-1 P49753-2 Explore the universe of human proteins at neXtProt for ACOT2: NX_P49753
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P49753
4/10 DME Specific Peptides for ACOT2 (P49753) (see all 10)
ACOT2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_006812.3
ENSEMBL proteins: ENSP00000440961 ENSP00000238651
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005739 | mitochondrion |
IDA | -- |
ACOT2 for ontologies About GeneDecksing
ACOT2 Antibody Products:
Assay Products for ACOT2: |
Protein
Domains /
Families
for ACOT2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ACOT2 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P49753ProtoNet protein and cluster: P49753 1 Blocks protein family: IPB006862 Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
UniProtKB/Swiss-Prot: ACOT2_HUMAN, P49753Similarity: Belongs to the C/M/P thioester hydrolase family |
Function
for ACOT2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ACOT2_HUMAN, P49753Function: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fattyacid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acidsand CoASH. Displays high levels of activity on medium- and long chain acyl CoAsCatalytic activity: Palmitoyl-CoA + H(2)O = CoA + palmitateBiophysicochemical properties: Kinetic parameters: KM=40.3 uM for C10-acyl-CoA; KM=8.9 uM for C12-acyl-CoA; KM=1.6 uMfor C14-acyl-CoA; KM=2.0 uM for C16-acyl-CoA; KM=2.8 uM for C18-acyl-CoA; KM=4.8 uM for C20-acyl-CoA; KM=4.5 uM forC16:1-acyl-CoA; KM=6.1 uM for C18:1-acyl-CoA; KM=4.3 uM for C18:1-trans-acyl-CoA; Vmax=212 nmol/min/mg enzyme towardC10-acyl-CoA; Vmax=681 nmol/min/mg enzyme toward C12-acyl-CoA; Vmax=766 nmol/min/mg enzyme toward C14-acyl-CoA;Vmax=656 nmol/min/mg enzyme toward C16-acyl-CoA; Vmax=488 nmol/min/mg enzyme toward C18-acyl-CoA; Vmax=408 nmol/min/mgenzyme toward C20-acyl-CoA; Vmax=661 nmol/min/mg enzyme toward C16:1-acyl-CoA; Vmax=304 nmol/min/mg enzyme towardC18:1-acyl-CoA; Vmax=418 nmol/min/mg enzyme toward C18:1-trans-acyl-CoA;Enzyme Number (IUBMB): EC 3.1.2.21 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ACOT2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ACOT2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ACOT2 (NM_006821) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ACOT2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACOT2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACOT2 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
ACOT2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ACOT2:
|
Pathways & Interactions
for ACOT2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Biosynthesis of unsaturated fatty acids | | | 2 | fatty acid alpha-oxidation II | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for ACOT2
1 
Kegg Pathway (Kegg details for ACOT2):
ACOT2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ACOT2
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
3 Interacting proteins for ACOT2 (P497533 ENSP000002386514) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
ACOT2 for ontologies About GeneDecksing
|
Drugs & Compounds
for ACOT2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ACOT2
10/68 HMDB Compounds for ACOT2 (see all 68) About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| (2E)-Decenoyl-CoA | (E)-S-2-decenoate Coenzyme A (see all 15) | 10018-95-8 | -- | | (2E)-Dodecenoyl-CoA | 2-trans-Dodecenoyl-Coenzyme A (see all 4) | 1066-12-2 | -- | | (2E)-Hexadecenoyl-CoA | trans-2-Hexadecenoyl-CoA (see all 4) | 4460-95-1 | -- | | (2E)-Octenoyl-CoA | (E)-S-2-octenoate Coenzyme A (see all 16) | 10018-94-7 | -- | | (2E)-Tetradecenoyl-CoA | (2E)-Tetradecenoyl-Coenzyme A (see all 8) | 38795-33-4 | -- | | 11'-Carboxy-alpha-chromanol | 2,5,7,8-Tetramethyl-2-(4',8'-dimethyl-11'-carboxy-undecyl)-6-chromanol;RRR-11'-carboxy-alpha-chromanol;2-(11-carboxy-4,8-dimethylundecyl)-6-hydroxy-2,5,7,8-tetramethylchroman;11'-carboxy-alpha-tocopherol | -- | -- | | 11'-Carboxy-alpha-tocotrienol | alpha-CDMD(en)(2)HC;2-(10-carboxy-4,8-dimethyl-(3E,7E)-decadienyl)-6-hydroxy-2,5,7,8-tetramethylchroman;alpha-CDMD(en)(,2)HC | -- | -- | | 11'-Carboxy-gama-chromanol | 2,7,8-trimethyl-2-(11'-carboxy-4',8'-dimethylundecyl)-6-chromanol;2,7,8-trimethyl-2-(11'-carboxy-4',8'-dimethylundecyl)-6-hydroxychroman;RRR-11'-carboxy-gama-chromanol;11'-Carboxy-gama-tocopherol | -- | -- | | 11'-carboxy-gama-tocotrienol | gama-CDMD(en)(2)HC;carboxydimethyldecadienyl hydroxychroman;2-(10-carboxy-4,8-dimethyl-(3E,7E)-decadienyl)-6-hydroxy-2,7,8-trimethylchroman | -- | -- | | 13'-carboxy-alpha-tocotrienol | 13AaTE | -- | -- |
Search CenterWatch for drugs/clinical trials and news about ACOT2
|
Transcripts
for ACOT2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ACOT2 gene: NM_006821.5 Unigene Cluster for ACOT2: Acyl-CoA thioesterase 2 Hs.446685 [show with all ESTs]Unigene Representative Sequence: NM_0068213 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000538782(uc001xom.3) ENST00000238651(uc001xon.4) ENST00000557857
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ACOT2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ACOT2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ACOT2 (NM_006821) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ACOT2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACOT2 |
Additional cDNA sequence: AK001939.1 AK093131.1 AK223635.1 AY005822.1 BC004436.1 BC006335.2 BC006500.2 BC144425.1 DQ082755.1 L40401.1 NR_046028.1 9 DOTS entries: DT.445656 DT.95157623 DT.100824506 DT.100824503 DT.100824504 DT.99970598 DT.100824510 DT.100824511 DT.86853383 24/403 AceView cDNA sequences (see all 403): BU517172 BQ424599 CB132001 CA390968 BM982293 CR599069 AA953357 BM795593 F25969 BI767427 F29758 BI759820 BQ021741 AA825544 CF530077 BM826236 BI819848 BQ051952 CB961857 BI821071 CR622314 BE312460 AK093131 BP340920
GeneLoc Exon Structure
|
Expression
for ACOT2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ACOT2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGCCTCTCT
About this image
See ACOT2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ACOT2
SOURCE GeneReport for Unigene cluster: Hs.446685
UniProtKB/Swiss-Prot: ACOT2_HUMAN, P49753Tissue specificity: Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas
SABiosciences Custom PCR Arrays for ACOT2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ACOT2
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat ACOT2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ACOT2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ACOT2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACOT2 |
Orthologs
for ACOT2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ACOT2 gene from 5/14 species (see all 14) About this table
ENSEMBL Gene Tree for ACOT2 (if available)
TreeFam Gene Tree for ACOT2 (if available) |
Paralogs
for ACOT2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ACOT2 gene
- ACOT62 ACOT42 ACOT12 BAAT2
4 SIMAP similar genes for ACOT2 using alignment to 2 protein entries: ACOT2_HUMAN (see all proteins):ACOT1 ACOT4 ACOT6 BAAT
ACOT2 for paralogs About GeneDecksing
|
Genomic Variants
for ACOT2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ACOT2 (74034324 - 74042359 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 17 variations for ACOT2
15/17 CNVs (see all 17): 23304 7039 3942 87270 87266 38871 30658 35268 58687 38974 66664 71919 87268 22908 71918 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ACOT2 |
|
Disorders
/ Diseases
for ACOT2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ACOT2 for disorders About GeneDecksing
OMIM gene information: 609972
OMIM disorders: --
2  diseases for ACOT2: About MalaCardsearly-onset familial alzheimer disease alzheimer's disease
Human Genome Epidemiology (HuGE) Navigator: ACOT2 (2 documents)
Export disorders for ACOT2 gene to outside databases
|
Publications
for ACOT2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ACOT2 gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with ACOT2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs. (PubMed id 16940157)1, 2, 3 Hunt M.C....Alexson S.E. (2006)
- Identification of PTE2, a human peroxisomal long-chain acyl-CoA thioesterase. (PubMed id 10944470)1, 2, 9 Jones J.M. and Gould S.J. (2000)
- A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases. (PubMed id 16103133)1, 3 Hunt M.C....Alexson S.E. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. (PubMed id 7596406)1, 2 Sherrington R....Holman K. (1995)
- Crystal structure of human mitochondrial acyl-CoA thi oesterase (ACOT2). (PubMed id 19497300)1, 9 Mandel C.R....Tong L. (2009)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
|
External Searches for ACOT2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ACOT2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ACOT2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ACOT2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ACOT2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ACOT2 gene:
Search GeneIP for patents involving ACOT2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ACOT2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ACOT2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ACOT2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ACOT2 | | OriGene 3'-UTR Clone for ACOT2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ACOT2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ACOT2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ACOT2 | | OriGene Custom Protein Services for ACOT2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ACOT2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ACOT2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ACOT2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ACOT2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ACOT2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ACOT2 |
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| | | | Search Tocris compounds for ACOT2 |
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 | | | ACOT2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACOT2 |
|  |  |  | | | | ThermoFisher Antibody for ACOT2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACOT2 |
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