AANAT Gene
protein-coding GIFtS: 60
GCID: GC17P074449
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|
aralkylamine N-acetyltransferase(Previous name: arylalkylamine N-acetyltransferase )
| |
Aliases
for AANAT gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Aralkylamine N-Acetyltransferase1 2 3 | | EC 2.3.1.873 8 | | SNAT1 2 3 5 | | DSPS2 | | Arylalkylamine N-Acetyltransferase1 2 | | Serotonin N-Acetyltransferase2 | | Serotonin Acetylase2 3 | | AA-NAT3 |
Export aliases for AANAT gene to outside databasesPrevious GC identifers: GC17P074297 GC17P077455 GC17P074927 GC17P075060 GC17P071975 GC17P069877 |
Summaries
for AANAT gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for AANAT:
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme inmelatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland.Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme isregulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects theenzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleepphase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.(provided by RefSeq, Oct 2009)
UniProtKB/Swiss-Prot: SNAT_HUMAN, Q16613Function: Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation ofserotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin
 summary
for AANAT: Arylalkylamine N-acetyltransferase (AANAT) is involved in the production of melatonin. It is expressed in
the pineal gland and retina, where its activity is highest at night or in darkness, and lowest during
daylight hours.
|
Genomic Views
for AANAT gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the AANAT gene promoter:
Pax-5 MIF-1 E47 CREB MZF-1 AREB6 Nkx6-1 deltaCREB Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for AANAT
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AANAT |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q25 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q25AANAT Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P074449: view genomic region
(about GC identifiers)
Start:
|
74,449,433 bp from pter |
End:
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74,466,199 bp from pter |
Size:
|
16,767 bases |
Orientation:
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plus strand |
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Proteins
for AANAT gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SNAT_HUMAN, Q16613 (See
protein sequence)Recommended Name: Serotonin N-acetyltransferase Size: 207 amino acids; 23344 Da
Subunit: Monomer (By similarity). Interacts with several 14-3-3 proteins, including YWHAB, YWHAE, YWHAG and YWHAZ,preferentially when phosphorylated at Thr-31. Phosphorylation on Ser-205 also allows binding to YWHAZ, but with loweraffinity. The interaction with YWHAZ considerably increases affinity for arylalkylamines and acetyl-CoA and protectsthe enzyme from dephosphorylation and proteasomal degradation (By similarity). It may also prevent thiol-dependentinactivation (By similarity)
Subcellular location: Cytoplasm
Secondary accessions: A0AVF2 Q562F4Explore the universe of human proteins at neXtProt for AANAT: NX_Q16613
Post-translational modifications:
cAMP-dependent phosphorylation on both N-terminal Thr-31 and C-terminal Ser-205 regulates AANAT activity by promotinginteraction with 14-3-3 proteins1
View neXtProt modification sites for NX_Q16613
4/5 DME Specific Peptides for AANAT (Q16613) (see all 5)
AANAT Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001079.1 NP_001160051.1
ENSEMBL proteins: ENSP00000250615 ENSP00000376282 ENSP00000468239 ENSP00000468717 Reactome Protein details: Q16613
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
AANAT for ontologies About GeneDecksing
AANAT Antibody Products:
Assay Products for AANAT: |
Protein
Domains /
Families
for AANAT gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
AANAT for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q16613ProtoNet protein and cluster: Q16613 1 Blocks protein family: IPB000182 GCN5-related N-acetyltransferase
UniProtKB/Swiss-Prot: SNAT_HUMAN, Q16613Similarity: Belongs to the acetyltransferase family. AANAT subfamilySimilarity: Contains 1 N-acetyltransferase domain |
Function
for AANAT gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SNAT_HUMAN, Q16613Function: Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation ofserotonin into N-acetylserotonin, the penultimate step in the synthesis of melatoninCatalytic activity: Acetyl-CoA + a 2-arylethylamine = CoA + an N-acetyl-2-arylethylamineBiophysicochemical properties: Kinetic parameters: KM=0.13 mM for tryptamine; KM=2.6 mM for 5-hydroxytryptamine;KM=0.55 mM for phenylethylamine; KM=10.6 mM for tyramine; Genatlas biochemistry entry for AANAT:arylalkylamine N-acetyltransferase,23kDa,expressed in the pineal gland,penultimate step in melatoninsynthesis,controlling the circadian rythm of production of melatonin,rhythmic activity controlled by ICER,an earlyresponse repressor
Enzyme Number (IUBMB): EC 2.3.1.871 2
Clone
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AANAT |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004059 | aralkylamine N-acetyltransferase activity |
NAS | 8661026 | | GO:0004060 | arylamine N-acetyltransferase activity |
-- | -- |
AANAT for ontologies About GeneDecksing
Animal Models:
1 MGI phenotypic allele  for Aanat (no phenotypes)
AANAT for phenotypes About GeneDecksing
|
Pathways & Interactions
for AANAT gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Regulation of thyroid hormone activity | | | 2 | Metabolism | | | 3 | Tryptophan metabolism | | | 4 | Metabolism of amino acids and derivatives | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3  BioSystems Pathways for AANAT
4 
Reactome Pathways for AANAT
2 
Kegg Pathways (Kegg details for AANAT):
UniProtKB/Swiss-Prot: SNAT_HUMAN, Q16613Pathway: Aromatic compound metabolism; melatonin biosynthesis; melatonin from serotonin: step 1/2
AANAT for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AANAT
STRING Interaction
Network Preview (showing 5 interactants - click image to see 10)
5/10 Interacting proteins for AANAT (Q166132, 3 ENSP000002506154) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
About this table
Gene Ontology (GO): 5/17 biological process terms (GO ID links to tree view) (see all 17): About this table
AANAT for ontologies About GeneDecksing
|
Drugs & Compounds
for AANAT gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
AANAT for compounds About GeneDecksing
Compounds for AANAT available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| N-Acetyltryptamine | Melatonin partial agonist (MT1/MT2). Also MT3 antagonist | [1016-47-3] |
7 HMDB Compounds for AANAT About this table
3 DrugBank Compounds for AANAT About this table
10/45 Novoseek chemical compound relationships for AANAT gene (see all 45) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| arylalkylamine |
98.5 |
194 |
17164235 (5), 15644438 (3), 7681102 (2), 11313340 (2) (see all 84) |
| melatonin |
92 |
344 |
12364461 (5), 18569588 (5), 12195298 (4), 19538336 (4) (see all 99) |
| n-acetyltryptamine |
88.3 |
3 |
9804794 (1), 2327568 (1) |
| n-acetylserotonin |
87.5 |
19 |
10024876 (1), 10722724 (1), 1977416 (1), 9804794 (1) (see all 9) |
| hydroxyindole |
81.6 |
1 |
18312298 (1) |
| tryptamine |
74.3 |
3 |
9804794 (1), 8520468 (1) |
| arylamine |
68.6 |
9 |
8382984 (2), 8520468 (2), 11393533 (1) |
| acetyl-coa |
65.1 |
16 |
7712152 (2), 9196290 (1), 10024876 (1), 10722724 (1) (see all 8) |
| cyclic amp |
62.8 |
28 |
10820191 (4), 7543927 (2), 11506377 (2), 7580870 (2) (see all 13) |
| quinpirole |
62.5 |
8 |
9181516 (2), 9029407 (2), 7909927 (1), 12658371 (1) |
Search CenterWatch for drugs/clinical trials and news about AANAT / SNAT
|
Transcripts
for AANAT gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for AANAT gene (2 alternative transcripts): NM_001088.2 NM_001166579.1 Unigene Cluster for AANAT: Aralkylamine N-acetyltransferase Hs.431417 [show with all ESTs]Unigene Representative Sequence: BC0924304 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000250615(uc021udg.1) ENST00000392492(uc002jro.3 uc010wte.2)
ENST00000587798 ENST00000585649
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AANAT (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AANAT (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): AANAT (NM_001088) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for AANAT | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AANAT |
Additional cDNA sequence: AB593119.1 AY055827.1 BC069434.1 BC092430.1 BC126332.1 BC126334.1 BC143989.1 U40347.1 3 DOTS entries: DT.208592 DT.100670397 DT.99981904 16 AceView cDNA sequences: U40347 BC069434 NM_001088 BX281912 BQ637944 AI819939 AY055827 BU931661 BU845764 AA084486 AA364412 AA365330 AA722177 BM711585 AW951264 AA757429
GeneLoc Exon Structure
|
Expression
for AANAT gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| AANAT expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGACAGCAG
About this image
See AANAT Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for AANAT
SOURCE GeneReport for Unigene cluster: Hs.431417
UniProtKB/Swiss-Prot: SNAT_HUMAN, Q16613Tissue specificity: Highly expressed in pineal gland and at lower levels in the retina. Weak expression in severalbrain regions and in the pituitary gland
SABiosciences Expression via Pathway-Focused PCR Arrays including AANAT:
Primer
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AANAT |
Orthologs
for AANAT gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for AANAT gene from 5/12 species (see all 12) About this table
ENSEMBL Gene Tree for AANAT (if available)
TreeFam Gene Tree for AANAT (if available) |
Paralogs
for AANAT gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for AANAT gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for AANAT (74449433 - 74466199 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for AANAT: --
Human Gene Mutation Database (HGMD): AANAT
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AANAT |
|
Disorders
/ Diseases
for AANAT gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
AANAT for disorders About GeneDecksing
OMIM gene information: 600950
OMIM disorders: --
UniProtKB/Swiss-Prot: SNAT_HUMAN, Q16613
Defects in AANAT are a cause of susceptibility to delayed sleep phase syndrome (DSPS) [MIM:614163]. Acircadian rhythm sleep disorder characterized by sleep-onset insomnia and difficulty in awakening at the desired time.Patients with DSPS have chronic difficulty in adjusting their sleep-onset and wake-up times to occupational, school,and social activities. Note=Susceptibility to delayed sleep phase syndrome can be conferred by variant Thr-129.Thr-129 shows a significantly higher frequency in affected individuals than in healthy controls
17  diseases for AANAT: About MalaCardsdelayed sleep phase syndrome genetic disease autism spectrum disorder bipolar i disorder
pineocytoma schizoaffective disorder insomnia scoliosis
retinoblastoma cholera cholangiocarcinoma prostate cancer
breast cancer asthma retinitis prostatitis
schizophrenia
6 Novoseek disease relationships for AANAT gene About this table
Genetic Association Database (GAD): AANAT
Human Genome Epidemiology (HuGE) Navigator: AANAT (14 documents)
Export disorders for AANAT gene to outside databases
|
Publications
for AANAT gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for AANAT gene, integrated from 9 sources (see all 173):
(articles sorted by number of sources associating them with AANAT) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human serotonin N-acetyltransferase (EC 2.3.1.87) gene (AANAT): structure, chromosomal localization, and tissue expression. (PubMed id 8661026)1, 2, 3, 9 Coon S.L....Rodriguez I.R. (1996)
- Significant association of the arylalkylamine N-acetyltransferase ( AA-NAT) gene with delayed sleep phase syndrome. (PubMed id 12736803)1, 2, 4, 9 Hohjoh H....Tokunaga K. (2003)
- cAmp regulation of arylalkylamine N-acetyltransferase (AANAT, EC 2.3.1.87): a new cell line (1E7) provides evidence of intracellular AANAT activation. (PubMed id 11313340)1, 2, 9 Coon S.L....Klein D.C. (2001)
- Genetic variability of arylalkylamine-N-acetyl-transferase (AA-NAT) gene and human sleep/wake pattern. (PubMed id 15332344)1, 4, 9 Wang G.Y....Lee E.J. (2004)
- Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis. (PubMed id 11427721)1, 2, 9 Ganguly S....Klein D.C. (2001)
- Identification of single-nucleotide polymorphisms (SNPs) of human N-acetyltransferase genes NAT1, NAT2, AANAT, ARD1 and L1CAM in the Japanese population. (PubMed id 11393533)1, 4, 9 Sekine A....Nakamura Y. (2001)
- A naturally occurring -263G/C variant of the human AA-NAT gene and overnight melatonin production. (PubMed id 14728993)1, 4, 9 Ying G.W....Lee E.J. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Arylalkylamine N-acetyltransferase (AANAT) genotype as a personal trait in melatonin synthesis. (PubMed id 18569588)1, 9 Blomeke B....Roemer H.C. (2008)
- Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation. (PubMed id 11336675)1, 9 Obsil T.... Dyda F. (2001)
|
External Searches for AANAT gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing AANAT gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing AANAT gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing AANAT gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for AANAT | Pharmacogenomics, SNPs, Pathways | | SHMPD | http://shmpd.bii.a-star.edu.sg/gene.php?genestart=A&genename=AANAT |
|
| | |
About This Section
| Patent Information for AANAT gene:
Search GeneIP for patents involving AANAT
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for AANAT gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for AANAT | | OriGene shRNA RFP for AANAT | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AANAT | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AANAT | | | OriGene Protein Over-expression Lysate for AANAT | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for AANAT | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AANAT | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AANAT | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for AANAT | | OriGene Custom Protein Services for AANAT | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat AANAT | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AANAT | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AANAT | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AANAT | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AANAT | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AANAT |
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| | | | Tocris compounds for AANAT |
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 | | | AANAT Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AANAT |
|  |  |  | | | | ThermoFisher Antibodies for AANAT |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AANAT |
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